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Protein

Histone deacetylase

Gene

SORBI_3007G114000

Organism
Sorghum bicolor (Sorghum) (Sorghum vulgare)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Hydrolysis of an N6-acetyl-lysine residue of a histone to yield a deacetylated histone.UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei112SubstrateUniRule annotation1
Active sitei154Proton acceptorUniRule annotation1
Binding sitei162Substrate; via carbonyl oxygenUniRule annotation1
Metal bindingi189Divalent metal cationUniRule annotation1
Metal bindingi191Divalent metal cationUniRule annotation1
Metal bindingi277Divalent metal cationUniRule annotation1
Binding sitei316SubstrateUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChromatin regulatorUniRule annotationSAAS annotation, HydrolaseUniRule annotationSAAS annotation
Biological processTranscription, Transcription regulationUniRule annotationSAAS annotation
LigandMetal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Histone deacetylaseUniRule annotationSAAS annotation (EC:3.5.1.98UniRule annotationSAAS annotation)
Gene namesi
ORF Names:SORBI_3007G114000Imported
OrganismiSorghum bicolor (Sorghum) (Sorghum vulgare)Imported
Taxonomic identifieri4558 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaePACMAD cladePanicoideaeAndropogonodaeAndropogoneaeSorghinaeSorghum
Proteomesi
  • UP000000768 Componenti: Chromosome 7

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusUniRule annotationSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi4558.Sb07g018230.1.

Structurei

3D structure databases

ProteinModelPortaliC5YKG8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini41 – 330Hist_deacetylInterPro annotationAdd BLAST290

Sequence similaritiesi

Belongs to the histone deacetylase family. HD Type 1 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiKOG1342. Eukaryota.
COG0123. LUCA.
HOGENOMiHOG000225180.
InParanoidiC5YKG8.
KOiK06067.
OMAiQNTNDYL.
OrthoDBiEOG093609CH.

Family and domain databases

Gene3Di3.40.800.20. 1 hit.
InterProiView protein in InterPro
IPR000286. His_deacetylse.
IPR003084. His_deacetylse_1.
IPR023801. His_deacetylse_dom.
IPR037138. His_deacetylse_dom_sf.
IPR023696. Ureohydrolase_dom_sf.
PANTHERiPTHR10625. PTHR10625. 1 hit.
PfamiView protein in Pfam
PF00850. Hist_deacetyl. 1 hit.
PIRSFiPIRSF037913. His_deacetylse_1. 1 hit.
PRINTSiPR01270. HDASUPER.
PR01271. HISDACETLASE.
SUPFAMiSSF52768. SSF52768. 1 hit.

Sequencei

Sequence statusi: Complete.

C5YKG8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAASGEGASL PSPAGGEDAH RRRVSYFYEP SIGDYYYGQG HPMKPHRIRM
60 70 80 90 100
AHSLVVHYGL HRLLELSRPY PASEADIRRF HSDDYVAFLA SATGNPSVLD
110 120 130 140 150
PRAVKRFNVG EDCPVFDGLF PFCQASAGGS IGAAVKLNRG DADITVNWAG
160 170 180 190 200
GLHHAKKSEA SGFCYVNDIV LAILELLKFH RRVLYVDIDV HHGDGVEEAF
210 220 230 240 250
FTTNRVMTVS FHKYGDFFPG TGHITDVGAA EGKHYALNVP LSDGIDDATF
260 270 280 290 300
RDLFQCIIKK VMEVYQPDVV VLQCGADSLA GDRLGCFNLS VKGHADCLRF
310 320 330 340 350
LRSYNVPMMV LGGGGYTIRN VARCWCYETA VAVGVEPDNK LPYNDYYEYF
360 370 380 390 400
GPDYILHIQP KSVENQNTTK DLENIKNMIL ESLSKIEHVP STQFHDRPSD
410 420 430 440 450
PEAPEEKEED MDKRPAQRSR LWSGGAYDSD TEDPDNLKSE SKDVTANLQM

KDEPKNDL
Length:458
Mass (Da):50,952
Last modified:September 1, 2009 - v1
Checksum:iC5CF51B33021A1C3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM000766 Genomic DNA. Translation: EES13744.1.
RefSeqiXP_002444249.1. XM_002444204.1.

Genome annotation databases

EnsemblPlantsiEES13744; EES13744; SORBI_007G114000.
GeneIDi8073075.
GrameneiEES13744; EES13744; SORBI_007G114000.
KEGGisbi:8073075.

Similar proteinsi

Entry informationi

Entry nameiC5YKG8_SORBI
AccessioniPrimary (citable) accession number: C5YKG8
Entry historyiIntegrated into UniProtKB/TrEMBL: September 1, 2009
Last sequence update: September 1, 2009
Last modified: November 22, 2017
This is version 52 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported