ID   C5YK81_SORBI            Unreviewed;       964 AA.
AC   C5YK81;
DT   01-SEP-2009, integrated into UniProtKB/TrEMBL.
DT   01-SEP-2009, sequence version 1.
DT   27-MAR-2024, entry version 76.
DE   RecName: Full=phosphoenolpyruvate carboxylase {ECO:0000256|ARBA:ARBA00012305};
DE            EC=4.1.1.31 {ECO:0000256|ARBA:ARBA00012305};
GN   ORFNames=SORBI_3007G106500 {ECO:0000313|EMBL:EES13699.1};
OS   Sorghum bicolor (Sorghum) (Sorghum vulgare).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; PACMAD clade;
OC   Panicoideae; Andropogonodae; Andropogoneae; Sorghinae; Sorghum.
OX   NCBI_TaxID=4558 {ECO:0000313|EMBL:EES13699.1, ECO:0000313|Proteomes:UP000000768};
RN   [1] {ECO:0000313|EMBL:EES13699.1, ECO:0000313|Proteomes:UP000000768}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. BTx623 {ECO:0000313|Proteomes:UP000000768};
RX   PubMed=19189423; DOI=10.1038/nature07723;
RA   Paterson A.H., Bowers J.E., Bruggmann R., Dubchak I., Grimwood J.,
RA   Gundlach H., Haberer G., Hellsten U., Mitros T., Poliakov A., Schmutz J.,
RA   Spannagl M., Tang H., Wang X., Wicker T., Bharti A.K., Chapman J.,
RA   Feltus F.A., Gowik U., Grigoriev I.V., Lyons E., Maher C.A., Martis M.,
RA   Narechania A., Otillar R.P., Penning B.W., Salamov A.A., Wang Y., Zhang L.,
RA   Carpita N.C., Freeling M., Gingle A.R., Hash C.T., Keller B., Klein P.,
RA   Kresovich S., McCann M.C., Ming R., Peterson D.G., Mehboob-ur-Rahman,
RA   Ware D., Westhoff P., Mayer K.F., Messing J., Rokhsar D.S.;
RT   "The Sorghum bicolor genome and the diversification of grasses.";
RL   Nature 457:551-556(2009).
RN   [2] {ECO:0000313|Proteomes:UP000000768}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. BTx623 {ECO:0000313|Proteomes:UP000000768};
RX   PubMed=29161754; DOI=10.1111/tpj.13781;
RA   McCormick R.F., Truong S.K., Sreedasyam A., Jenkins J., Shu S., Sims D.,
RA   Kennedy M., Amirebrahimi M., Weers B.D., McKinley B., Mattison A.,
RA   Morishige D.T., Grimwood J., Schmutz J., Mullet J.E.;
RT   "The Sorghum bicolor reference genome: improved assembly, gene annotations,
RT   a transcriptome atlas, and signatures of genome organization.";
RL   Plant J. 93:338-354(2018).
CC   -!- FUNCTION: Through the carboxylation of phosphoenolpyruvate (PEP) it
CC       forms oxaloacetate, a four-carbon dicarboxylic acid source for the
CC       tricarboxylic acid cycle. {ECO:0000256|ARBA:ARBA00003774}.
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|ARBA:ARBA00001946};
CC   -!- SUBUNIT: Homotetramer. {ECO:0000256|ARBA:ARBA00011881}.
CC   -!- SIMILARITY: Belongs to the PEPCase type 1 family.
CC       {ECO:0000256|ARBA:ARBA00008346}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CM000766; EES13699.1; -; Genomic_DNA.
DR   RefSeq; XP_002444204.1; XM_002444159.1.
DR   AlphaFoldDB; C5YK81; -.
DR   STRING; 4558.C5YK81; -.
DR   EnsemblPlants; EES13699; EES13699; SORBI_3007G106500.
DR   GeneID; 8069872; -.
DR   Gramene; EES13699; EES13699; SORBI_3007G106500.
DR   KEGG; sbi:8069872; -.
DR   eggNOG; ENOG502QPVS; Eukaryota.
DR   HOGENOM; CLU_006557_1_0_1; -.
DR   InParanoid; C5YK81; -.
DR   OMA; WKSIPTT; -.
DR   OrthoDB; 355614at2759; -.
DR   BRENDA; 4.1.1.31; 5768.
DR   Proteomes; UP000000768; Chromosome 7.
DR   ExpressionAtlas; C5YK81; baseline and differential.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0008964; F:phosphoenolpyruvate carboxylase activity; IBA:GO_Central.
DR   GO; GO:0015977; P:carbon fixation; IEA:UniProtKB-KW.
DR   GO; GO:0048366; P:leaf development; IBA:GO_Central.
DR   GO; GO:0015979; P:photosynthesis; IEA:UniProtKB-KW.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR   Gene3D; 1.20.1440.90; Phosphoenolpyruvate/pyruvate domain; 1.
DR   HAMAP; MF_00595; PEPcase_type1; 1.
DR   InterPro; IPR021135; PEP_COase.
DR   InterPro; IPR022805; PEP_COase_bac/pln-type.
DR   InterPro; IPR018129; PEP_COase_Lys_AS.
DR   InterPro; IPR033129; PEPCASE_His_AS.
DR   InterPro; IPR015813; Pyrv/PenolPyrv_Kinase-like_dom.
DR   PANTHER; PTHR30523; PHOSPHOENOLPYRUVATE CARBOXYLASE; 1.
DR   PANTHER; PTHR30523:SF33; PHOSPHOENOLPYRUVATE CARBOXYLASE 3; 1.
DR   Pfam; PF00311; PEPcase; 1.
DR   PRINTS; PR00150; PEPCARBXLASE.
DR   SUPFAM; SSF51621; Phosphoenolpyruvate/pyruvate domain; 1.
DR   PROSITE; PS00781; PEPCASE_1; 1.
DR   PROSITE; PS00393; PEPCASE_2; 1.
PE   3: Inferred from homology;
KW   Allosteric enzyme {ECO:0000256|ARBA:ARBA00022533};
KW   Carbon dioxide fixation {ECO:0000256|ARBA:ARBA00023300};
KW   Lyase {ECO:0000256|ARBA:ARBA00023239};
KW   Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW   Photosynthesis {ECO:0000256|ARBA:ARBA00022531};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000768}.
FT   ACT_SITE        171
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU10111"
FT   ACT_SITE        599
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU10112"
SQ   SEQUENCE   964 AA;  110057 MW;  258016A3481F1C52 CRC64;
     MAGKLEKMAS IDAQLRMLAP AKLSEDDKLV EYDALLLDRF LDILQDLHGE DLRELVQECY
     EIAAEYERKH DSEKLDELGN MLTSLDPGDS IVTAKAFSHM LNLANLAEEV QIAYRRRIKL
     KKGDFADENS ALTESDIEET FKRLVVDLKK SPAEVFDALK SQTVDLVLTA HPTQSVRRSL
     LQKHSRIRNC LVQLCSKDIT PDDKQELDEA LQREIQAAFR TDEIRRTQPT PQDEMRAGMS
     YFHETIWKGV PKFLRRVDTA LKNIGIDERV PYNAPLIQFS SWMGGDRDGN PRVTPEVTRD
     VCLLARMMAA NLYCSQIENL MFELSMWRCN DELRAQADEL HRSSKKDAKH YIEFWKKVPP
     SEPYRVILGD LRDKLYNTRE RARQLLSSGY SDIPEESTVT NVEQFLEPLE LCYRSLCACG
     DRVIADGSLL DFLRQVSTFG LCLVRLDIRQ ESDRHTDVLD AITTYLGIGS YREWSEERRQ
     EWLLSELNGK RPLFGPDLPT TDEIADVLDT FRVIAELPAD NFGAYIISMA TAPSDVLAVE
     LLQRECHVKT PLRVVPLFEK LADLEGAPAA LARLFSVDWY RERINGKQEV MIGYSDSGKD
     AGRLSAAWQL YKAQEELIKV AKKFGVKLTM FHGRGGTVGR GGGPTHLAIL SQPPDTIHGS
     LRVTVQGEVI EQSFGEEHLC FRTLQRFTAA TLEHGMHPPI SPKPEWRALL DEMAVVATKE
     YRSIVFQEPR FVEYFRLATP EMEYGRMNIG SRPSKRKPSG GIESLRAIPW IFAWTQTRFH
     LPVWLGFGAA FKHILEKDIR NLHMLQEMYN EWPFFRVTID LVEMVFAKGD PGIAALYDKL
     LVSSELWPLG EKLRANYEET KRLLLQVAGH KDLLEGDLYL KQRLRLRDAY ITTLNVCQAY
     TMKRIRDPDY HVTLRPHLSK EIMDWNKPAA ELVKLNPTSE YAPGLEDTLI LTMKGIAAGM
     QNTG
//