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Protein

Histone deacetylase

Gene

SORBI_3006G067600

Organism
Sorghum bicolor (Sorghum) (Sorghum vulgare)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Hydrolysis of an N6-acetyl-lysine residue of a histone to yield a deacetylated histone.UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei95SubstrateUniRule annotation1
Active sitei137Proton acceptorUniRule annotation1
Binding sitei145Substrate; via carbonyl oxygenUniRule annotation1
Metal bindingi172Divalent metal cationUniRule annotation1
Metal bindingi174Divalent metal cationUniRule annotation1
Metal bindingi261Divalent metal cationUniRule annotation1
Binding sitei300SubstrateUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChromatin regulatorUniRule annotationSAAS annotation, HydrolaseUniRule annotationSAAS annotation
Biological processTranscription, Transcription regulationUniRule annotationSAAS annotation
LigandMetal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Histone deacetylaseUniRule annotationSAAS annotation (EC:3.5.1.98UniRule annotationSAAS annotation)
Gene namesi
ORF Names:SORBI_3006G067600Imported
OrganismiSorghum bicolor (Sorghum) (Sorghum vulgare)Imported
Taxonomic identifieri4558 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaePACMAD cladePanicoideaeAndropogonodaeAndropogoneaeSorghinaeSorghum
Proteomesi
  • UP000000768 Componenti: Chromosome 6

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusUniRule annotationSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi4558.Sb06g015420.1.

Structurei

3D structure databases

ProteinModelPortaliC5YFT2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini24 – 314Hist_deacetylInterPro annotationAdd BLAST291

Sequence similaritiesi

Belongs to the histone deacetylase family. HD Type 1 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiKOG1342. Eukaryota.
COG0123. LUCA.
HOGENOMiHOG000225180.
InParanoidiC5YFT2.
KOiK06067.
OMAiPRAWTHL.
OrthoDBiEOG093609CH.

Family and domain databases

Gene3Di3.40.800.20. 1 hit.
InterProiView protein in InterPro
IPR000286. His_deacetylse.
IPR003084. His_deacetylse_1.
IPR023801. His_deacetylse_dom.
PANTHERiPTHR10625. PTHR10625. 1 hit.
PfamiView protein in Pfam
PF00850. Hist_deacetyl. 1 hit.
PIRSFiPIRSF037913. His_deacetylse_1. 1 hit.
PRINTSiPR01270. HDASUPER.
PR01271. HISDACETLASE.

Sequencei

Sequence statusi: Complete.

C5YFT2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLEKDRISYF YDGDVGNVYF GPNHPMKPHR LCMTHHLVLS YGLHKKMEIY
60 70 80 90 100
RPHKAYPIEL AQFHSADYVE FLHRITPDTQ HLYASELTRY NLGEDCPVFD
110 120 130 140 150
NLFEFCQIYT GGTLDAARRL NHKTCDIAIN WAGGLHHAKK CEASGFCYIN
160 170 180 190 200
DLVLGILELL KYHARVLYID IDVHHGDGVE EAFYFTDRVM TVSFHKYGDL
210 220 230 240 250
FFPGTGDIKD IGEREGKYYA INIPLKDGID DSSFTRLFKT IIAKVIETYL
260 270 280 290 300
PGAIVLQCGA DSLARDRLGC FNLSIEGHAE CVKFVKKFNI PLLVTGGGGY
310 320 330 340 350
TKENVARCWA VETGVLLDTE LPNEIPNNEY IEYFAPDYTL KVPNLNMDNL
360 370 380 390 400
NSKTYLSSIK VQVMESLRSI QHAPGVQMQE VPPDFYIPDF DEDELDPDER
410 420 430
VDQHTQDKQI HRDDEYYEGD NDNDHDDGAR
Length:430
Mass (Da):49,217
Last modified:September 1, 2009 - v1
Checksum:i5799C024B651F3C0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM000765 Genomic DNA. Translation: EES10729.1.
RefSeqiXP_002446401.1. XM_002446356.1.

Genome annotation databases

EnsemblPlantsiEES10729; EES10729; SORBI_006G067600.
GeneIDi8075265.
GrameneiEES10729; EES10729; SORBI_006G067600.
KEGGisbi:SORBI_06g015420.

Similar proteinsi

Entry informationi

Entry nameiC5YFT2_SORBI
AccessioniPrimary (citable) accession number: C5YFT2
Entry historyiIntegrated into UniProtKB/TrEMBL: September 1, 2009
Last sequence update: September 1, 2009
Last modified: September 27, 2017
This is version 49 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported