C5XHC8 (C5XHC8_SORBI) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Eukaryotic translation initiation factor 6 HAMAP-Rule MF_03132
Short name=eIF-6 HAMAP-Rule MF_03132

Gene names

Name:	Sb03g011410 EMBL EES02790.1
Synonyms:	EIF6 HAMAP-Rule MF_03132, EIF6-1
ORF Names:	SORBIDRAFT_03g011410 EMBL EES02790.1

Organism

Sorghum bicolor (Sorghum) (Sorghum vulgare) [Reference proteome]

Taxonomic identifier

4558 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › Liliopsida › commelinids › Poales › Poaceae › PACMAD clade › Panicoideae › Andropogoneae › Sorghum

Protein attributes

Sequence length	257 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis By similarity. HAMAP-Rule MF_03132
Subunit structure	Monomer. Associates with the 60S ribosomal subunit By similarity. HAMAP-Rule MF_03132
Subcellular location	Cytoplasm. Nucleus › nucleolus. Note: Shuttles between cytoplasm and nucleus/nucleolus By similarity. HAMAP-Rule MF_03132
Sequence similarities	Belongs to the eIF-6 family. HAMAP-Rule MF_03132

Ontologies

Keywords
Biological process	Protein biosynthesis Ribosome biogenesis HAMAP-Rule MF_03132
Cellular component	Cytoplasm HAMAP-Rule MF_03132 Nucleus HAMAP-Rule MF_03132
Molecular function	Initiation factor HAMAP-Rule MF_03132
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	mature ribosome assembly Inferred from electronic annotation. Source: HAMAP ribosomal large subunit biogenesis Inferred from electronic annotation. Source: HAMAP
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell nucleolus Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ribosomal large subunit binding Inferred from electronic annotation. Source: HAMAP ribosome binding Inferred from electronic annotation. Source: InterPro translation initiation factor activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C5XHC8 [UniParc]. Last modified September 1, 2009. Version 1. Checksum: 6DD2937B50820C0F	FASTA	257	27,322
	10 20 30 40 50 60 MASRVKFENS CEVGVFARLT NAYCLVPAGA ASQGFYSVLE GELAGAVPVV RTSVAGTRIV 70 80 90 100 110 120 GRLCVGNKRG LLLPHTATDQ EIQHLRNSLP DEVVVKCVDE RLSALGNCIA CNDHVALTHP 130 140 150 160 170 180 DLDKETEEVI SDVLGVEVFR QTIAGNILVG SYCTFTNKGG LVHPQTSVED LDELSTLLQV 190 200 210 220 230 240 PMVAGTVNRG SEVVSAGMAV NDWTAFCGSD TTATEVSVVE SVFRLRDPRA GALGSVQDFF 250 TSGAGLLPEP RQKTRLC

References

[1]

"The Sorghum bicolor genome and the diversification of grasses." Paterson A.H., Bowers J.E., Bruggmann R., Dubchak I., Grimwood J., Gundlach H., Haberer G., Hellsten U., Mitros T., Poliakov A., Schmutz J., Spannagl M., Tang H., Wang X., Wicker T., Bharti A.K., Chapman J., Feltus F.A. , Gowik U., Grigoriev I.V., Lyons E., Maher C.A., Martis M., Narechania A., Otillar R.P., Penning B.W., Salamov A.A., Wang Y., Zhang L., Carpita N.C., Freeling M., Gingle A.R., Hash C.T., Keller B., Klein P., Kresovich S., McCann M.C., Ming R., Peterson D.G., Mehboob-ur-Rahman M., Ware D., Westhoff P., Mayer K.F.X., Messing J., Rokhsar D.S. Nature 457:551-556(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. BTx623.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CM000762 Genomic DNA. Translation: EES02790.1.
RefSeq	XP_002457670.1. XM_002457625.1.
UniGene	Sbi.5473.
3D structure databases
ProteinModelPortal	C5XHC8.
ModBase	Search...
Protein-protein interaction databases
STRING	4558.Sb03g011410.1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	Sb03g011410.1; Sb03g011410.1; Sb03g011410.
GeneID	8078117.
KEGG	sbi:SORBI_03g011410.
Organism-specific databases
Gramene	C5XHC8.
Phylogenomic databases
eggNOG	COG1976.
HOGENOM	HOG000230605.
KO	K03264.
OMA	MAVNDWT.
ProtClustDB	CLSN2683375.
Family and domain databases
HAMAP	MF_00032. eIF_6.
InterPro	IPR002769. eIF6. [Graphical view]
PANTHER	PTHR10784. PTHR10784. 1 hit.
Pfam	PF01912. eIF-6. 1 hit. [Graphical view]
PIRSF	PIRSF006413. IF-6. 1 hit.
SMART	SM00654. eIF6. 1 hit. [Graphical view]
TIGRFAMs	TIGR00323. eIF-6. 1 hit.
ProtoNet	Search...

Entry information

Entry name

C5XHC8_SORBI

Accession

Primary (citable) accession number: C5XHC8

Entry history

Integrated into UniProtKB/TrEMBL:	September 1, 2009
Last sequence update:	September 1, 2009
Last modified:	April 3, 2013
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)