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Protein

Eukaryotic translation initiation factor 6

Gene

EIF6

Organism
Sorghum bicolor (Sorghum) (Sorghum vulgare)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionInitiation factorUniRule annotation
Biological processProtein biosynthesis, Ribosome biogenesisUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Eukaryotic translation initiation factor 6UniRule annotation
Short name:
eIF-6UniRule annotation
Gene namesi
Name:EIF6UniRule annotation
ORF Names:SORBI_3003G134100Imported
OrganismiSorghum bicolor (Sorghum) (Sorghum vulgare)Imported
Taxonomic identifieri4558 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaePACMAD cladePanicoideaeAndropogonodaeAndropogoneaeSorghinaeSorghum
Proteomesi
  • UP000000768 Componenti: Chromosome 3

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

CytoplasmUniRule annotation, NucleusUniRule annotation

Interactioni

Subunit structurei

Monomer. Associates with the 60S ribosomal subunit.UniRule annotation

Protein-protein interaction databases

STRINGi4558.Sb03g011410.1.

Structurei

3D structure databases

ProteinModelPortaliC5XHC8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the eIF-6 family.UniRule annotation

Phylogenomic databases

eggNOGiKOG3185. Eukaryota.
COG1976. LUCA.
HOGENOMiHOG000230605.
InParanoidiC5XHC8.
KOiK03264.
OMAiLCVGNKR.
OrthoDBiEOG09360JT2.

Family and domain databases

CDDicd00527. IF6. 1 hit.
HAMAPiMF_00032. eIF_6. 1 hit.
InterProiView protein in InterPro
IPR002769. eIF6.
PANTHERiPTHR10784. PTHR10784. 1 hit.
PfamiView protein in Pfam
PF01912. eIF-6. 1 hit.
PIRSFiPIRSF006413. IF-6. 1 hit.
SMARTiView protein in SMART
SM00654. eIF6. 1 hit.
TIGRFAMsiTIGR00323. eIF-6. 1 hit.

Sequencei

Sequence statusi: Complete.

C5XHC8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASRVKFENS CEVGVFARLT NAYCLVPAGA ASQGFYSVLE GELAGAVPVV
60 70 80 90 100
RTSVAGTRIV GRLCVGNKRG LLLPHTATDQ EIQHLRNSLP DEVVVKCVDE
110 120 130 140 150
RLSALGNCIA CNDHVALTHP DLDKETEEVI SDVLGVEVFR QTIAGNILVG
160 170 180 190 200
SYCTFTNKGG LVHPQTSVED LDELSTLLQV PMVAGTVNRG SEVVSAGMAV
210 220 230 240 250
NDWTAFCGSD TTATEVSVVE SVFRLRDPRA GALGSVQDFF TSGAGLLPEP

RQKTRLC
Length:257
Mass (Da):27,322
Last modified:September 1, 2009 - v1
Checksum:i6DD2937B50820C0F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM000762 Genomic DNA. Translation: EES02790.1.
RefSeqiXP_002457670.1. XM_002457625.1.
UniGeneiSbi.5473.

Genome annotation databases

EnsemblPlantsiEES02790; EES02790; SORBI_003G134100.
GeneIDi8078117.
GrameneiEES02790; EES02790; SORBI_003G134100.
KEGGisbi:SORBI_03g011410.

Similar proteinsi

Entry informationi

Entry nameiC5XHC8_SORBI
AccessioniPrimary (citable) accession number: C5XHC8
Entry historyiIntegrated into UniProtKB/TrEMBL: September 1, 2009
Last sequence update: September 1, 2009
Last modified: September 27, 2017
This is version 52 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported