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Protein
Submitted name:

Multimodular transpeptidase-transglycosylase

Gene

pbp1A

Organism
Streptococcus dysgalactiae subsp. equisimilis (strain GGS_124)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

Pathwayi: peptidoglycan biosynthesis

This protein is involved in the pathway peptidoglycan biosynthesis, which is part of Cell wall biogenesis.SAAS annotation
View all proteins of this organism that are known to be involved in the pathway peptidoglycan biosynthesis and in Cell wall biogenesis.

GO - Molecular functioni

Keywordsi

Molecular functionTransferaseSAAS annotation
Biological processCell shape, Cell wall biogenesis/degradationSAAS annotation, Peptidoglycan synthesisSAAS annotation

Enzyme and pathway databases

BioCyciSDYS486410:GHH8-1709-MONOMER.
UniPathwayiUPA00219.

Protein family/group databases

CAZyiGT51. Glycosyltransferase Family 51.

Names & Taxonomyi

Protein namesi
Submitted name:
Multimodular transpeptidase-transglycosylaseImported
Gene namesi
Name:pbp1AImported
Ordered Locus Names:SDEG_1711Imported
OrganismiStreptococcus dysgalactiae subsp. equisimilis (strain GGS_124)Imported
Taxonomic identifieri486410 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
Proteomesi
  • UP000002732 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei12 – 39HelicalSequence analysisAdd BLAST28

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

Structurei

3D structure databases

ProteinModelPortaliC5WIH9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini63 – 239TransglyInterPro annotationAdd BLAST177
Domaini335 – 632TranspeptidaseInterPro annotationAdd BLAST298

Sequence similaritiesi

Belongs to the glycosyltransferase 51 family.SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

HOGENOMiHOG000041140.
KOiK05366.
OMAiGINQAVE.

Family and domain databases

Gene3Di1.10.3810.10. 1 hit.
InterProiView protein in InterPro
IPR001264. Glyco_trans_51.
IPR001460. PCN-bd_Tpept.
PfamiView protein in Pfam
PF00912. Transgly. 1 hit.
PF00905. Transpeptidase. 1 hit.

Sequencei

Sequence statusi: Complete.

C5WIH9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MITIKNPKIL KWLKYVLGAI LSLTILVIVI GGLLFAFYIS SAPKLSEAEL
60 70 80 90 100
KSTNSSLVYD GNNNLIADLG SEKRENVTAD SIPINLVNAI TSIEDKRFFN
110 120 130 140 150
HRGVDLYRIF GAAFHNLTSK TTQGGSTLDQ QLIKLAYFST NESDQTLKRK
160 170 180 190 200
AQEVWLALQM ERKYTKQEIL TFYINKVYMG NGNYGMLTAA KSYYGKDLKD
210 220 230 240 250
LSYAQLALLA GIPQAPSQYD PYTQPEAAQN RRNIVLQQMY MEKNITKAEY
260 270 280 290 300
EAALATPVAD GLQPLQQRST YPKYMDNYLK QVIGEVKKET NKDIFTSGLK
310 320 330 340 350
VYTNIIPEAQ QTLYNIYNSE DYVYYPDKDF QVASTIVDVT NGHVIAQLGG
360 370 380 390 400
RNQDENVSFG TNQAVLTDRD WGSTMKPITD YAPAIESGAY NSTAQSTNDS
410 420 430 440 450
VYYWPGTTTQ LYNWDRKYNG WMTIQSALML SRNVPAVKAL DAAGLDYARS
460 470 480 490 500
FLSGLGINYP EMHYSNAISS NNSSSEAKYG ASSEKMAAAY AAFANGGIYY
510 520 530 540 550
KPQYVNKIEF SDGTSKVFEE KGKRAMKETT AYMMTDMLKT VLTYGTGTAA
560 570 580 590 600
AIPGVAQAGK TGTSNYTDEE LAKIGEKYGL YPDYVGTMAP DENFVGYTNQ
610 620 630 640 650
YAMAVWTGYK NRLTPVYGYG LEIAADVYRN MMTYLTNGYS EDWTMPSGLY
660 670 680 690 700
RSGGFLYLSG TYASNNDYTN SVYNNLYGNN TSTSSSQSSS DDSTDSTDAT
710 720
DANTSTNTEN GAEHSANEDK KTNH
Length:724
Mass (Da):80,343
Last modified:September 1, 2009 - v1
Checksum:i838E929DC4FE000B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP010935 Genomic DNA. Translation: BAH82194.1.
RefSeqiWP_012767434.1. NC_012891.1.

Genome annotation databases

EnsemblBacteriaiBAH82194; BAH82194; SDEG_1711.
KEGGisds:SDEG_1711.
PATRICi19643718. VBIStrDys95162_1684.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP010935 Genomic DNA. Translation: BAH82194.1.
RefSeqiWP_012767434.1. NC_012891.1.

3D structure databases

ProteinModelPortaliC5WIH9.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

CAZyiGT51. Glycosyltransferase Family 51.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAH82194; BAH82194; SDEG_1711.
KEGGisds:SDEG_1711.
PATRICi19643718. VBIStrDys95162_1684.

Phylogenomic databases

HOGENOMiHOG000041140.
KOiK05366.
OMAiGINQAVE.

Enzyme and pathway databases

UniPathwayiUPA00219.
BioCyciSDYS486410:GHH8-1709-MONOMER.

Family and domain databases

Gene3Di1.10.3810.10. 1 hit.
InterProiView protein in InterPro
IPR001264. Glyco_trans_51.
IPR001460. PCN-bd_Tpept.
PfamiView protein in Pfam
PF00912. Transgly. 1 hit.
PF00905. Transpeptidase. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiC5WIH9_STRDG
AccessioniPrimary (citable) accession number: C5WIH9
Entry historyiIntegrated into UniProtKB/TrEMBL: September 1, 2009
Last sequence update: September 1, 2009
Last modified: May 10, 2017
This is version 53 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.