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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Streptococcus dysgalactiae subsp. equisimilis (strain GGS_124)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei160UniRule annotation1
Active sitei606UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyaseUniRule annotationSAAS annotationImported
Biological processCarbon dioxide fixationUniRule annotationSAAS annotation
LigandMagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciSDYS486410:GHH8-620-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotationImported
Ordered Locus Names:SDEG_0621Imported
OrganismiStreptococcus dysgalactiae subsp. equisimilis (strain GGS_124)Imported
Taxonomic identifieri486410 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
Proteomesi
  • UP000002732 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotationSAAS annotation

Phylogenomic databases

HOGENOMiHOG000238647.
KOiK01595.
OMAiFTSNWEL.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1. 1 hit.
InterProiView protein in InterPro
IPR021135. PEP_COase.
IPR022805. PEP_COase_bac/pln-type.
IPR018129. PEP_COase_Lys_AS.
IPR033129. PEPCASE_His_AS.
PfamiView protein in Pfam
PF00311. PEPcase. 1 hit.
PRINTSiPR00150. PEPCARBXLASE.
PROSITEiView protein in PROSITE
PS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.

Sequencei

Sequence statusi: Complete.

C5WFF8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLSFLVKSGM IKREANRGGV NSLSLKKLES SNNQAIIAEE VAILKDMLEK
60 70 80 90 100
ITRRMIGDEA FATIETIVAL SEKQDYVGLE TIIASISNQD MDVISRYFSI
110 120 130 140 150
LPLLINISED VDLAYEINYQ NNANKDYLGK LALTIDAVAE KENAKDILEQ
160 170 180 190 200
VNVVPVLTAH PTQVQRKTIL ELTTHIHDLL RKYRDVKAGV VNQEKWHNEL
210 220 230 240 250
YRYIEIIMQT DIIREKKLKV KNEITNVMQY YNGSLIQAVT KLTTEYKNLA
260 270 280 290 300
QKRGLDLVNP NPITMGMWIG GDRDGNPFVT AETLRLSATV QSEVILNYYI
310 320 330 340 350
EKLAALYRTF SLSSTLIQPS AEVERLASLS QDQSIYRENE PYRRAFHYVK
360 370 380 390 400
SRLVQTRTQL TGDQDTTGQS LTAGRLTRQL AMQDQLEGPI AAYVSPEDFK
410 420 430 440 450
ADLMAIEQSL LSNGDVALVD GDLREVMQAV DIFGFFLASI DMRQDSSVQE
460 470 480 490 500
ACVAELLKGA NIVEDYSSLS ETEKCDLLVK QLTEDPRTLS SAAVAKSDLL
510 520 530 540 550
EKELAIYAAA RELKDKLGDE VIKQHIISHT ESVSDMFELA IMLKEVGLID
560 570 580 590 600
QHKARVQIVP LFETIEDLDN ARDIMTTYLS YDMVKSWIAA NHNYQEIMLG
610 620 630 640 650
YSDSNKDGGY LASGWTLYKA QNELTAIGEE NGVKITFFHG RGGTVGRGGG
660 670 680 690 700
PSYDAITSQP FGSIKDRIRL TEQGEIIENK YGNKDVAYYH LEMLISASIN
710 720 730 740 750
RMVTQMLTNP NEIDGFREVM DGIVADSNKI YRQLVFDNPH FYDYFFEASP
760 770 780 790 800
IKEVSSLNIG SRPAARKTIT EITGLRAIPW VFSWSQNRIM FPGWYGVGSA
810 820 830 840 850
FKHYIDQAEG NLERLQHMYQ TWPFFHSLLS NVDMVLSKSN MNIAFQYAQL
860 870 880 890 900
ADSQEVRDVF HVILDEWQLT KNVILAIEGH EELLEDNPSL KQSLAFRLPY
910 920 930 940
FNVLNYIQIE LIKRLRNHQL REEDEKLIHT TINGIATGLR NSG
Length:943
Mass (Da):106,767
Last modified:September 1, 2009 - v1
Checksum:i488E1FB46BDFC463
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP010935 Genomic DNA. Translation: BAH81123.1.

Genome annotation databases

EnsemblBacteriaiBAH81123; BAH81123; SDEG_0621.
KEGGisds:SDEG_0621.
PATRICi19641489. VBIStrDys95162_0586.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP010935 Genomic DNA. Translation: BAH81123.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAH81123; BAH81123; SDEG_0621.
KEGGisds:SDEG_0621.
PATRICi19641489. VBIStrDys95162_0586.

Phylogenomic databases

HOGENOMiHOG000238647.
KOiK01595.
OMAiFTSNWEL.

Enzyme and pathway databases

BioCyciSDYS486410:GHH8-620-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1. 1 hit.
InterProiView protein in InterPro
IPR021135. PEP_COase.
IPR022805. PEP_COase_bac/pln-type.
IPR018129. PEP_COase_Lys_AS.
IPR033129. PEPCASE_His_AS.
PfamiView protein in Pfam
PF00311. PEPcase. 1 hit.
PRINTSiPR00150. PEPCARBXLASE.
PROSITEiView protein in PROSITE
PS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiC5WFF8_STRDG
AccessioniPrimary (citable) accession number: C5WFF8
Entry historyiIntegrated into UniProtKB/TrEMBL: September 1, 2009
Last sequence update: September 1, 2009
Last modified: February 15, 2017
This is version 59 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.