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C5VWZ7

- C5VWZ7_STRSE

UniProt

C5VWZ7 - C5VWZ7_STRSE

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Protein

Phenylalanine--tRNA ligase alpha subunit

Gene

pheS

Organism
Streptococcus suis (strain P1/7)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl-tRNA(Phe).UniRule annotationSAAS annotation

Cofactori

Note: Binds 2 magnesium ions per tetramer.UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi262 – 2621MagnesiumUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. magnesium ion binding Source: UniProtKB-HAMAP
  3. phenylalanine-tRNA ligase activity Source: UniProtKB-HAMAP
  4. tRNA binding Source: InterPro

GO - Biological processi

  1. phenylalanyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetaseUniRule annotationSAAS annotation, Ligase

Keywords - Biological processi

Protein biosynthesisUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, MagnesiumUniRule annotationSAAS annotation, Metal-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciSSUI218494:GJDS-1043-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phenylalanine--tRNA ligase alpha subunitUniRule annotation (EC:6.1.1.20UniRule annotation)
Alternative name(s):
Phenylalanyl-tRNA synthetase alpha subunitUniRule annotation
Gene namesi
Name:pheSUniRule annotationImported
Ordered Locus Names:SSU0997Imported
OrganismiStreptococcus suis (strain P1/7)Imported
Taxonomic identifieri218494 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000002055: Chromosome

Subcellular locationi

Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Tetramer of two alpha and two beta subunits.UniRule annotationSAAS annotation

Protein-protein interaction databases

STRINGi218494.SSU0997.

Family & Domainsi

Sequence similaritiesi

Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0016.
HOGENOMiHOG000242675.
KOiK01889.
OMAiIRYFFEN.
OrthoDBiEOG6WX4QN.

Family and domain databases

HAMAPiMF_00281. Phe_tRNA_synth_alpha1.
InterProiIPR006195. aa-tRNA-synth_II.
IPR004529. Phe-tRNA-synth_IIc_asu.
IPR004188. Phe-tRNA_ligase_II_N.
IPR022911. Phe_tRNA_ligase_alpha1_bac.
IPR002319. Phenylalanyl-tRNA_Synthase.
IPR010978. tRNA-bd_arm.
[Graphical view]
PfamiPF02912. Phe_tRNA-synt_N. 1 hit.
PF01409. tRNA-synt_2d. 1 hit.
[Graphical view]
SUPFAMiSSF46589. SSF46589. 1 hit.
TIGRFAMsiTIGR00468. pheS. 1 hit.
PROSITEiPS50862. AA_TRNA_LIGASE_II. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C5VWZ7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSNIEQQLAE LSQTTLEKLK EIQHQGEKEL QDLRVAVLGK KGSLTDLLKG
60 70 80 90 100
LKDLSNDMKP IVGKQVNEVR DVLTTAFEET AQKVAAAKIQ QQLASETIDV
110 120 130 140 150
TLPGRQVKVG KRHVLTQTSE EIEDIFLGMG FQIVDGFEVE KDYYNFERMN
160 170 180 190 200
LPKDHPARDM QDTFYITEEI LMRTHTSPVQ ARTMDQHDFS KGALKMISPG
210 220 230 240 250
RVFRRDTDDA THSHQFHQIE GLVVGENVSM GDLKGTLEMI IKKMFGEERQ
260 270 280 290 300
IRLRPSYFPF TEPSVEVDVS CFKCGGDGCN VCKKTGWIEI LGAGMVHPQV
310 320 330 340
LEMSGIDSTK YSGFAFGLGQ ERIAMLRYGI NDIRGFYQGD VRFSEQF
Length:347
Mass (Da):39,209
Last modified:September 1, 2009 - v1
Checksum:iE7BBDD7F94A56936
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM946016 Genomic DNA. Translation: CAR46091.1.
RefSeqiYP_003026859.1. NC_012925.1.

Genome annotation databases

EnsemblBacteriaiCAR46091; CAR46091; SSU0997.
GeneIDi8151608.
KEGGissi:SSU0997.
PATRICi19786900. VBIStrSui84581_0956.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM946016 Genomic DNA. Translation: CAR46091.1 .
RefSeqi YP_003026859.1. NC_012925.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 218494.SSU0997.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAR46091 ; CAR46091 ; SSU0997 .
GeneIDi 8151608.
KEGGi ssi:SSU0997.
PATRICi 19786900. VBIStrSui84581_0956.

Phylogenomic databases

eggNOGi COG0016.
HOGENOMi HOG000242675.
KOi K01889.
OMAi IRYFFEN.
OrthoDBi EOG6WX4QN.

Enzyme and pathway databases

BioCyci SSUI218494:GJDS-1043-MONOMER.

Family and domain databases

HAMAPi MF_00281. Phe_tRNA_synth_alpha1.
InterProi IPR006195. aa-tRNA-synth_II.
IPR004529. Phe-tRNA-synth_IIc_asu.
IPR004188. Phe-tRNA_ligase_II_N.
IPR022911. Phe_tRNA_ligase_alpha1_bac.
IPR002319. Phenylalanyl-tRNA_Synthase.
IPR010978. tRNA-bd_arm.
[Graphical view ]
Pfami PF02912. Phe_tRNA-synt_N. 1 hit.
PF01409. tRNA-synt_2d. 1 hit.
[Graphical view ]
SUPFAMi SSF46589. SSF46589. 1 hit.
TIGRFAMsi TIGR00468. pheS. 1 hit.
PROSITEi PS50862. AA_TRNA_LIGASE_II. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: P1/7Imported.

Entry informationi

Entry nameiC5VWZ7_STRSE
AccessioniPrimary (citable) accession number: C5VWZ7
Entry historyi
Integrated into UniProtKB/TrEMBL: September 1, 2009
Last sequence update: September 1, 2009
Last modified: November 26, 2014
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3