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Protein

Nicotinate phosphoribosyltransferase

Gene

pncB

Organism
Acidovorax delafieldii 2AN
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.UniRule annotationSAAS annotation

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Catalytic activityi

Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate.UniRule annotationSAAS annotation

Pathwayi: NAD(+) biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes nicotinate D-ribonucleotide from nicotinate.UniRule annotationSAAS annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Nicotinate phosphoribosyltransferase (pncB)
This subpathway is part of the pathway NAD(+) biosynthesis, which is itself part of Cofactor biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes nicotinate D-ribonucleotide from nicotinate, the pathway NAD(+) biosynthesis and in Cofactor biosynthesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferaseImported, LigaseUniRule annotationSAAS annotationImported, Transferase
Biological processPyridine nucleotide biosynthesisUniRule annotationSAAS annotation

Enzyme and pathway databases

UniPathwayiUPA00253; UER00457

Names & Taxonomyi

Protein namesi
Recommended name:
Nicotinate phosphoribosyltransferaseUniRule annotationSAAS annotation (EC:6.3.4.21UniRule annotationSAAS annotation)
Short name:
NAPRTaseUniRule annotation
Gene namesi
Name:pncBUniRule annotation
ORF Names:AcdelDRAFT_0968Imported
OrganismiAcidovorax delafieldii 2ANImported
Taxonomic identifieri573060 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesComamonadaceaeAcidovorax
Proteomesi
  • UP000003856 Componenti: Unassembled WGS sequence

Structurei

3D structure databases

ProteinModelPortaliC5T238
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the NAPRTase family.UniRule annotationSAAS annotation

Phylogenomic databases

OrthoDBiPOG091H0197

Family and domain databases

CDDicd01401 PncB_like, 1 hit
HAMAPiMF_00570 NAPRTase, 1 hit
InterProiView protein in InterPro
IPR006406 Nic_PRibTrfase
IPR007229 Nic_PRibTrfase-Fam
IPR036068 Nicotinate_pribotase_like_C
PANTHERiPTHR11098 PTHR11098, 1 hit
PfamiView protein in Pfam
PF04095 NAPRTase, 1 hit
PIRSFiPIRSF000484 NAPRT, 1 hit
SUPFAMiSSF51690 SSF51690, 1 hit
TIGRFAMsiTIGR01514 NAPRTase, 1 hit

Sequencei

Sequence statusi: Complete.

C5T238-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIITSLLDTD LYKFTMMQVV LHQFPGARVE YRFKCRNPGV QLAPFVGEIR
60 70 80 90 100
DEIRSLCSLH FQEAELDYLR SLRFIKSDFV DFLGLFKLNE KYITVMPLES
110 120 130 140 150
GEIDITIRGP WLHTILFEIP VLAIVNEVYF RNTQKVPDFP EGRKRLDVKI
160 170 180 190 200
AQLQGEGLDE LKIADYGTRR RFSRAWHEEV LRVLVARLGA GDRRPGGGAG
210 220 230 240 250
PGQFAGTSNV LYAMKLGVTP LGTMAHEYLQ ACQSLGPRLR DSQVFGFEMW
260 270 280 290 300
AKEYRGDLGI ALSDVYGMSA FLRDFDLYFC KLFDGARHDS GDPFAWGERL
310 320 330 340 350
LEHYRHNRVD PLTKTLIFSD ALTVPRTIEL YRQFHGRCLL AFGIGTNLTN
360 370 380 390 400
DLGYEPLQVV IKMTRCNDQP VAKVSDTPGK GMCDDEKYLA YLRQVFEIPS

VP
Length:402
Mass (Da):45,856
Last modified:September 1, 2009 - v1
Checksum:i61F5937F5437717A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ACQT01000016 Genomic DNA Translation: EER61451.1
RefSeqiWP_005793957.1, NZ_ACQT01000016.1

Genome annotation databases

EnsemblBacteriaiEER61451; EER61451; AcdelDRAFT_0968
PATRICifig|573060.9.peg.4212

Similar proteinsi

Entry informationi

Entry nameiC5T238_ACIDE
AccessioniPrimary (citable) accession number: C5T238
Entry historyiIntegrated into UniProtKB/TrEMBL: September 1, 2009
Last sequence update: September 1, 2009
Last modified: April 25, 2018
This is version 55 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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