C5QPX2 (C5QPX2_STAEP) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Arginine--tRNA ligase HAMAP-Rule MF_00123
EC=6.1.1.19 HAMAP-Rule MF_00123

Alternative name(s):
Arginyl-tRNA synthetase HAMAP-Rule MF_00123

Gene names

Name:	argS HAMAP-Rule MF_00123 EMBL EES41056.1
ORF Names:	HMPREF0793_1278 EMBL EES41056.1

Organism

Staphylococcus epidermidis M23864:W1 EMBL EES41056.1

Taxonomic identifier

525378 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Bacillales › Staphylococcaceae › Staphylococcus › Staphylococcus epidermidis

Protein attributes

Sequence length	553 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123
Subunit structure	Monomer By similarity. HAMAP-Rule MF_00123
Subcellular location	Cytoplasm By similarity HAMAP-Rule MF_00123.
Sequence similarities	Belongs to the class-I aminoacyl-tRNA synthetase family. HAMAP-Rule MF_00123 RuleBase RU003489

Ontologies

Keywords
Biological process	Protein biosynthesis HAMAP-Rule MF_00123 RuleBase RU003489
Cellular component	Cytoplasm HAMAP-Rule MF_00123
Ligand	ATP-binding HAMAP-Rule MF_00123 RuleBase RU003489 Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase HAMAP-Rule MF_00123 RuleBase RU003489 EMBL EES41056.1 Ligase
Gene Ontology (GO)
Biological_process	arginyl-tRNA aminoacylation Inferred from electronic annotation. Source: HAMAP
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ATP binding Inferred from electronic annotation. Source: HAMAP arginine-tRNA ligase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Motif	130 – 140	11	"HIGH" region By similarity HAMAP-Rule MF_00123

Sequences

	Sequence		Length	Mass (Da)
	C5QPX2 [UniParc]. Last modified September 1, 2009. Version 1. Checksum: 7C448430C7530E9D	FASTA	553	62,640
	10 20 30 40 50 60 MNIIDQVKQT LIEEIEASIK KARLAEDIPE IKIEIPKDTK NGDYSSNIAM VLTKIAKRNP 70 80 90 100 110 120 REIAQAIVDH LDTSKAHVKE VDIAGPGFIN FYLDNHYLTE VIPEAIHKGD KFGYADEPKN 130 140 150 160 170 180 KNILLEYVSA NPTGDLHIGH ARNAAVGDSL ANILIAAGYN VTREYYINDA GNQITNLARS 190 200 210 220 230 240 IETRYFEALG DTSHEMPEDG YNGKDIIEIG KDLADKHPEI KDYSDEERLK TFRQLGVDYE 250 260 270 280 290 300 MDKLKKDLAA FNVHFDNWFS ETSLYENGAI DNTLAKMKEL GYTYEADGAT WLRTSDFKDD 310 320 330 340 350 360 KDRVLIKKDG NYTYFTPDTA YHYNKINRGN DILIDLMGAD HHGYINRLKA SLETFGVDSD 370 380 390 400 410 420 RLEIQIMQMV RLMQNGEEVK MSKRTGNAIT LREIMDEVGI DAARYFLTMR SPDSHFDFDL 430 440 450 460 470 480 ELAKEQSQDN PIYYAQYAHA RICSILKQAK EQGVEITTDA DFTTITNEKA IELLKKVAEF 490 500 510 520 530 540 ETTIESAAEH RAPHRLTNYI QDLASAFHKF YNAEKVLTDD AEKTKAHVAM IEAVRITLHN 550 ALTLVGVTAP ESM

References

[1]

Qin X., Bachman B., Battles P., Bell A., Bess C., Bickham C., Chaboub L., Chen D., Coyle M., Deiros D.R., Dinh H., Forbes L., Fowler G., Francisco L., Fu Q., Gubbala S., Hale W., Han Y. , Hemphill L., Highlander S.K., Hirani K., Hogues M., Jackson L., Jakkamsetti A., Javaid M., Jiang H., Korchina V., Kovar C., Lara F., Lee S., Mata R., Mathew T., Moen C., Morales K., Munidasa M., Nazareth L., Ngo R., Nguyen L., Okwuonu G., Ongeri F., Patil S., Petrosino J., Pham C., Pham P., Pu L.-L., Puazo M., Raj R., Reid J., Rouhana J., Saada N., Shang Y., Simmons D., Thornton R., Warren J., Weissenberger G., Zhang J., Zhang L., Zhou C., Zhu D., Muzny D., Worley K., Gibbs R. Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: M23864:W1 EMBL EES41056.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	ACJB01000050 Genomic DNA. Translation: EES41056.1.
3D structure databases
ProteinModelPortal	C5QPX2.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EES41056; EES41056; HMPREF0793_1278.
PATRIC	31394381. VBIStaEpi14170_1057.
Family and domain databases
Gene3D	3.30.1360.70. 1 hit. 3.40.50.620. 1 hit.
HAMAP	MF_00123. Arg_tRNA_synth.
InterPro	IPR001412. aa-tRNA-synth_I_CS. IPR001278. Arg-tRNA-ligase_Ia. IPR015945. Arg-tRNA-synth_Ia_core. IPR005148. Arg-tRNA-synth_N. IPR008909. DALR_anticod-bd. IPR014729. Rossmann-like_a/b/a_fold. IPR009080. tRNAsynth_1a_anticodon-bd. [Graphical view]
PANTHER	PTHR11956. PTHR11956. 1 hit.
Pfam	PF03485. Arg_tRNA_synt_N. 1 hit. PF05746. DALR_1. 1 hit. PF00750. tRNA-synt_1d. 1 hit. [Graphical view]
PRINTS	PR01038. TRNASYNTHARG.
SMART	SM01016. Arg_tRNA_synt_N. 1 hit. SM00836. DALR_1. 1 hit. [Graphical view]
SUPFAM	SSF55190. Arg-tRNA-synth_Ic_N. 1 hit. SSF47323. tRNAsyn_1a_bind. 1 hit.
TIGRFAMs	TIGR00456. argS. 1 hit.
PROSITE	PS00178. AA_TRNA_LIGASE_I. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

C5QPX2_STAEP

Accession

Primary (citable) accession number: C5QPX2

Entry history

Integrated into UniProtKB/TrEMBL:	September 1, 2009
Last sequence update:	September 1, 2009
Last modified:	April 3, 2013
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)