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Protein

Histone-lysine N-methyltransferase

Gene

CPC735_057720

Organism
Coccidioides posadasii (strain C735) (Valley fever fungus)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

Catalytic activityi

S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].SAAS annotation

GO - Molecular functioni

  1. histone-lysine N-methyltransferase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

MethyltransferaseUniRule annotationSAAS annotation, Transferase

Keywords - Ligandi

S-adenosyl-L-methionineSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Histone-lysine N-methyltransferaseSAAS annotation (EC:2.1.1.43SAAS annotation)
Gene namesi
ORF Names:CPC735_057720Imported
OrganismiCoccidioides posadasii (strain C735) (Valley fever fungus)Imported
Taxonomic identifieri222929 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeOnygenalesmitosporic OnygenalesCoccidioides
ProteomesiUP000009084 Componenti: Unassembled WGS sequence

Organism-specific databases

EuPathDBiFungiDB:CPC735_057720.

Subcellular locationi

GO - Cellular componenti

  1. nucleus Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

NucleusSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi222929.C5PIP9.

Family & Domainsi

Sequence similaritiesi

Contains 1 SET domain.UniRule annotation
Contains 1 post-SET domain.UniRule annotation

Phylogenomic databases

eggNOGiCOG2940.
KOiK06101.
OrthoDBiEOG7P8PH3.

Family and domain databases

InterProiIPR006560. AWS_dom.
IPR003616. Post-SET_dom.
IPR001214. SET_dom.
[Graphical view]
PfamiPF00856. SET. 1 hit.
[Graphical view]
SMARTiSM00508. PostSET. 1 hit.
SM00317. SET. 1 hit.
[Graphical view]
PROSITEiPS51215. AWS. 1 hit.
PS50868. POST_SET. 1 hit.
PS50280. SET. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C5PIP9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARDPMLSPS STPTSSALDS DATAIDATVP VLTPATSISE QSTPVDTEKD
60 70 80 90 100
GEHRAKKAKP SRRVTRSSLK NGELEANGGG EAMLTRPNDG SLDNTNTQED
110 120 130 140 150
EDCTSLLNGA EDASGSVDKQ SGKNAKAAGK KPNKKAGNKS PKRRSTRLSL
160 170 180 190 200
LAKTKDLAQS APSVLGKRTL DAISKSKDKV KTIDRKASLR PRVENERKEA
210 220 230 240 250
STPAPQEPSP KKRRVSGDNK STCQVPRQEQ TATRENSLIR QKRKPWLKHG
260 270 280 290 300
LYAGQEYIDS SVPKSKRGTR DAKNNGQQSQ VFPFPMYAGA RLLENGRAYK
310 320 330 340 350
LPFDIFSPLP HGQPKPNEWR KANKNVFVGD AASIWKAAKI KEHSTCTCTP
360 370 380 390 400
ETGCDENCQN RYMFYECDDT NCKLGSELCR NRPFSALRRR AKAGGKFNIG
410 420 430 440 450
VEVIKTEDRG YGVRSNRSFD PNQIIVEYTG EILTQEECER RMRTVYKKNE
460 470 480 490 500
CYYLMYFDQN MVIDATRGSI ARFINHSCEP NCRMEKWTVA GKPRMALFAG
510 520 530 540 550
EDGIMTGEEL TYDYNFDPYS QKNVQECRCG APTCRGVLGP RPKESWKNKD
560 570 580 590 600
KEKKSAPAAK RKVDSALDES ASRLNKKPKP SRASSLKTGV KKAVSKARTA
610 620 630 640 650
LKSTQAKGKV KRVGRPAKKA ASIKPIPVKK RRSTLTRAKM PVKSASKSAE
660 670 680 690 700
GDEKPPRNKG RKLKMPSKPR LGNSIAAARA SNKTPALMRK FLEAGDTKGG
710 720 730 740
AKVVSDTIKP GRKIRAARTA DVRSSPDNVP VSRKRGRAKK TL
Length:742
Mass (Da):81,822
Last modified:September 1, 2009 - v1
Checksum:i68B23FA93A627716
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ACFW01000049 Genomic DNA. Translation: EER24402.1.
RefSeqiXP_003066547.1. XM_003066501.1.
UniGeneiCpo.6924.

Genome annotation databases

GeneIDi9692017.
KEGGicpw:CPC735_057720.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ACFW01000049 Genomic DNA. Translation: EER24402.1.
RefSeqiXP_003066547.1. XM_003066501.1.
UniGeneiCpo.6924.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi222929.C5PIP9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi9692017.
KEGGicpw:CPC735_057720.

Organism-specific databases

EuPathDBiFungiDB:CPC735_057720.

Phylogenomic databases

eggNOGiCOG2940.
KOiK06101.
OrthoDBiEOG7P8PH3.

Family and domain databases

InterProiIPR006560. AWS_dom.
IPR003616. Post-SET_dom.
IPR001214. SET_dom.
[Graphical view]
PfamiPF00856. SET. 1 hit.
[Graphical view]
SMARTiSM00508. PostSET. 1 hit.
SM00317. SET. 1 hit.
[Graphical view]
PROSITEiPS51215. AWS. 1 hit.
PS50868. POST_SET. 1 hit.
PS50280. SET. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C735Imported.

Entry informationi

Entry nameiC5PIP9_COCP7
AccessioniPrimary (citable) accession number: C5PIP9
Entry historyi
Integrated into UniProtKB/TrEMBL: September 1, 2009
Last sequence update: September 1, 2009
Last modified: April 29, 2015
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.