Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

DNA ligase

Gene

CPC735_055100

Organism
Coccidioides posadasii (strain C735) (Valley fever fungus)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. DNA binding Source: InterPro
  3. DNA ligase (ATP) activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA biosynthetic process Source: InterPro
  2. DNA ligation involved in DNA repair Source: InterPro
  3. DNA recombination Source: UniProtKB-KW
  4. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotationImported

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
ORF Names:CPC735_055100Imported
OrganismiCoccidioides posadasii (strain C735) (Valley fever fungus)Imported
Taxonomic identifieri222929 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeOnygenalesmitosporic OnygenalesCoccidioides
ProteomesiUP000009084: Unassembled WGS sequence

Interactioni

Protein-protein interaction databases

STRINGi222929.C5PHY7.

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1793.
KOiK10747.
OrthoDBiEOG7TXKRG.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProiIPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 2 hits.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C5PHY7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRLSRFCLTR SKTTLAPLIY GQPTSIRFSC SVSSYFVIQR RGYTLITTNM
60 70 80 90 100
AQKSERKQTT LGKFFGGNAA SLPETKNQST LSFSSEAGSA KSETKPAKDL
110 120 130 140 150
QDNEDDDVDM EDSSRDIPTK TGPVTPTKNG TVCSRPASPG APRVDSDEEI
160 170 180 190 200
KSESARSESA SPSARKLKRQ KDSVVEESDG NESEPVTKRR RGPTKPKTES
210 220 230 240 250
STSKPAAGRK NRKASPRGKT NDKGATSTPN KQLEINESAV GNAESSESDQ
260 270 280 290 300
DDLLSESSSE ELDIKPEKEE KKKNTASKQR QKVQATLKSS ANDPYPDWKA
310 320 330 340 350
GDPVPYAALC TTFSLVEMTT KRLAILAHCS LFLRQVLRLT PEDLLPTVQL
360 370 380 390 400
MINKLAADYA GIELGIGESL IMKAIGESTG RSLAVIKADQ HEIGDLGLVA
410 420 430 440 450
AKSRSNQPTM FKPKPLTVRG VHESLLAIAK MQGHGSQEKK VGGIKKLLSS
460 470 480 490 500
ADSATAGKGS KGIDITKNKG GPSEAKYIVR FLEGKLRLGL ADKTVLVALA
510 520 530 540 550
HAMVAHETLS KGNKTPSAEQ LAKGEAILKQ VYSELPSYEV IIPAMLEHGI
560 570 580 590 600
FNLQENCKLQ PGVPLKPMLA KPTKSISEVL DRFEGKDFTC EYKYDGERAQ
610 620 630 640 650
IHYVSQDAIK DYTATAGTLQ KDGKGLCAIF SRNSEDLSKK YPDVLDKLES
660 670 680 690 700
WVRPGTKSFV LDCETVAWDL ENKKVLPFQQ LMTRKRKDVK AEDIKVRVCI
710 720 730 740 750
FAFDILFLNG APTVKMTFRE RRALLHETFV PTEGEFAFAQ YGNTSNVEEI
760 770 780 790 800
QTLLDESVKS SCEGLMVKML DTEESGYEPS KRSRNWLKVK KDYLAGIGDS
810 820 830 840 850
LDLVVIGAYF GKGKRTSVYG AFLLAAYNPS TENYETICNI GTGFSDALLD
860 870 880 890 900
ELHKSLSPLA ISQPKPFYSH SSVPKDQPDV WFEPRLVWEV KAADLTISPR
910 920 930 940 950
YRCASDEVMG MAGADGKGVS LRFPRYIKAR DDKKPDQAST TRMVAEMYRK
960
QESVTKEDKG KGVDDDWEY
Length:969
Mass (Da):106,658
Last modified:September 1, 2009 - v1
Checksum:iC5B76E247A0E5ACF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ACFW01000049 Genomic DNA. Translation: EER24140.1.
RefSeqiXP_003066285.1. XM_003066239.1.
UniGeneiCpo.3953.

Genome annotation databases

GeneIDi9691755.
KEGGicpw:CPC735_055100.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ACFW01000049 Genomic DNA. Translation: EER24140.1.
RefSeqiXP_003066285.1. XM_003066239.1.
UniGeneiCpo.3953.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi222929.C5PHY7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi9691755.
KEGGicpw:CPC735_055100.

Phylogenomic databases

eggNOGiCOG1793.
KOiK10747.
OrthoDBiEOG7TXKRG.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProiIPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 2 hits.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C735Imported.

Entry informationi

Entry nameiC5PHY7_COCP7
AccessioniPrimary (citable) accession number: C5PHY7
Entry historyi
Integrated into UniProtKB/TrEMBL: September 1, 2009
Last sequence update: September 1, 2009
Last modified: February 4, 2015
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.