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C5PCZ0 (DPEP1_COCP7) Reviewed, UniProtKB/Swiss-Prot

Last modified January 22, 2014. Version 20. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative dipeptidase CPC735_015490

EC=3.4.13.19
Gene names
ORF Names:CPC735_015490
OrganismCoccidioides posadasii (strain C735) (Valley fever fungus) [Complete proteome]
Taxonomic identifier222929 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeOnygenalesmitosporic OnygenalesCoccidioides

Protein attributes

Sequence length444 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Hydrolyzes a wide range of dipeptides By similarity.

Catalytic activity

Hydrolysis of dipeptides.

Cofactor

Zinc By similarity.

Sequence similarities

Belongs to the peptidase M19 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 3434 Potential
Chain35 – 444410Putative dipeptidase CPC735_015490
PRO_0000411213

Sites

Metal binding671Zinc 1; catalytic By similarity
Metal binding691Zinc 1; catalytic By similarity
Metal binding1781Zinc 1; catalytic By similarity
Metal binding1781Zinc 2; catalytic By similarity
Metal binding2501Zinc 2; catalytic By similarity
Metal binding2711Zinc 2; catalytic By similarity
Binding site2051Substrate By similarity
Binding site2821Substrate By similarity
Binding site3421Substrate By similarity

Amino acid modifications

Glycosylation4131N-linked (GlcNAc...) Potential
Disulfide bond118 ↔ 207 By similarity

Sequences

Sequence LengthMass (Da)Tools
C5PCZ0 [UniParc].

Last modified September 1, 2009. Version 1.
Checksum: 139F0A86FA3F1B87

FASTA44449,351
        10         20         30         40         50         60 
MSQRTEHNGS WLRNAGSLLS VLACVAVLAS PASATPASAA AAAAPRTDDY LKRAERILKF 

        70         80         90        100        110        120 
TPLIDGHNDL PNFIRKTTKN QIYEGKIPFE DELPGHTDLK RLRKGRVGGQ FWSVYTPCPD 

       130        140        150        160        170        180 
PPVPIDNPTW SVRDTLEQID VTKRLIEKYS RDLQFCGDAR CARRAFRRGK IASFLGIEGG 

       190        200        210        220        230        240 
HQIGNSLGDL RRVYELGVRY ITVTHNCDNA FATAQSTVAD GLPDTGLMKP FGIEFVKEMN 

       250        260        270        280        290        300 
RLGMLVDLSH VSANTMRDTL KVARAPVIFS HSSAYAVSNH LRNVPDDVLK EVAKNNGVVM 

       310        320        330        340        350        360 
VTFVSRFVNV ENPDAADINT VVDHIFHIAK VAGWDHVGIG GDYDGTVYLP KGLEDVSKYP 

       370        380        390        400        410        420 
HLIARVLERG ATTQQVRKLV GENILRVWTE VERIAKRLQK TELPNEAYWE GRNWTRPAKR 

       430        440 
DLNADFEGRS VPLFTSASNG DFCD 

« Hide

References

[1]"Comparative genomic analyses of the human fungal pathogens Coccidioides and their relatives."
Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R., Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y., McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M., Barker B.M., Galgiani J.N. expand/collapse author list , Orbach M.J., Kirkland T.N., Cole G.T., Henn M.R., Birren B.W., Taylor J.W.
Genome Res. 19:1722-1731(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: C735.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
ACFW01000043 Genomic DNA. Translation: EER24951.1.
RefSeqXP_003067096.1. XM_003067050.1.

3D structure databases

ProteinModelPortalC5PCZ0.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID9692567.
KEGGcpw:CPC735_015490.

Phylogenomic databases

eggNOGCOG2355.
KOK01273.
OrthoDBEOG7XM371.

Family and domain databases

InterProIPR028536. Dpep1-like.
IPR000180. Renal_dipep_AS.
IPR008257. Renal_dipep_fam.
[Graphical view]
PANTHERPTHR10443. PTHR10443. 1 hit.
PTHR10443:SF12. PTHR10443:SF12. 1 hit.
PfamPF01244. Peptidase_M19. 1 hit.
[Graphical view]
PROSITEPS00869. RENAL_DIPEPTIDASE_1. 1 hit.
PS51365. RENAL_DIPEPTIDASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDPEP1_COCP7
AccessionPrimary (citable) accession number: C5PCZ0
Entry history
Integrated into UniProtKB/Swiss-Prot: July 27, 2011
Last sequence update: September 1, 2009
Last modified: January 22, 2014
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Peptidase families

Classification of peptidase families and list of entries