SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

C5PCN6

- DPEP2_COCP7

UniProt

C5PCN6 - DPEP2_COCP7

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Putative dipeptidase CPC735_014430

Gene
CPC735_014430
Organism
Coccidioides posadasii (strain C735) (Valley fever fungus)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Hydrolyzes a wide range of dipeptides By similarity.

Catalytic activityi

Hydrolysis of dipeptides.

Cofactori

Zinc By similarity.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi93 – 931Zinc 1; catalytic By similarity
Metal bindingi95 – 951Zinc 1; catalytic By similarity
Metal bindingi206 – 2061Zinc 1; catalytic By similarity
Metal bindingi206 – 2061Zinc 2; catalytic By similarity
Binding sitei233 – 2331Substrate By similarity
Metal bindingi277 – 2771Zinc 2; catalytic By similarity
Metal bindingi298 – 2981Zinc 2; catalytic By similarity
Binding sitei309 – 3091Substrate By similarity
Binding sitei369 – 3691Substrate By similarity

GO - Molecular functioni

  1. dipeptidase activity Source: UniProtKB-KW
  2. dipeptidyl-peptidase activity Source: InterPro
  3. metal ion binding Source: UniProtKB-KW
  4. metalloexopeptidase activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Dipeptidase, Hydrolase, Metalloprotease, Protease

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Putative dipeptidase CPC735_014430 (EC:3.4.13.19)
Gene namesi
ORF Names:CPC735_014430
OrganismiCoccidioides posadasii (strain C735) (Valley fever fungus)
Taxonomic identifieri222929 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeOnygenalesmitosporic OnygenalesCoccidioides
ProteomesiUP000009084: Unassembled WGS sequence

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei40 – 5617Helical; Reviewed predictionAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 464464Putative dipeptidase CPC735_014430PRO_0000411216Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi145 ↔ 235 By similarity
Glycosylationi382 – 3821N-linked (GlcNAc...) Reviewed prediction

Keywords - PTMi

Disulfide bond, Glycoprotein

Structurei

3D structure databases

ProteinModelPortaliC5PCN6.

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase M19 family.

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG2355.
KOiK01273.
OrthoDBiEOG7XM371.

Family and domain databases

InterProiIPR000180. Dipep_AS.
IPR008257. Renal_dipep_fam.
[Graphical view]
PANTHERiPTHR10443. PTHR10443. 1 hit.
PfamiPF01244. Peptidase_M19. 1 hit.
[Graphical view]
PROSITEiPS00869. RENAL_DIPEPTIDASE_1. 1 hit.
PS51365. RENAL_DIPEPTIDASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C5PCN6-1 [UniParc]FASTAAdd to Basket

« Hide

MSTMSARDNE KGSARSQPSH AAASEIENVP RPSRQQSWTG TMIKVFIICA    50
CAGIVSKYII PLDSIFKSVH IDPHDYATRA NRILSTTPLI DGHNDLPYLI 100
RLETKNKIYD HEKLPFRTGL LSHTDQIKIQ EGKLGGQFWS VFVECATDPN 150
AEIDDPTWAV RDTLEQIDVT KRLVQEYPDL LEYCESASCA KAAFKRGKVG 200
SFLGIEGGHQ IGNSLASLRQ VYDLGVRYIT VTHNCDNAFA TAASTVAVGK 250
PDLGLTDFGR EFVKEMNRLG MLVDLSHVSH QTMRDILSVT KAPVMFSHSS 300
SYALSKHLRN VPDDVLNGVT KNGGVVMVTF VPSFLKVDDP ASATIHDAVD 350
HILHVAKVAG WDHVGIGSDF DGTADVPEGL ENVSKYPRLI ELLLERGVTD 400
EQARKLIGEN ILRVWSNVEE IAENIRALGE KPNEETWSGR KWTAAIDIPM 450
PFMFKDSADK RKEL 464
Length:464
Mass (Da):51,382
Last modified:September 1, 2009 - v1
Checksum:i632DEA67DC973F69
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
ACFW01000043 Genomic DNA. Translation: EER24847.1.
RefSeqiXP_003066992.1. XM_003066946.1.
UniGeneiCpo.5191.

Genome annotation databases

GeneIDi9692463.
KEGGicpw:CPC735_014430.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
ACFW01000043 Genomic DNA. Translation: EER24847.1 .
RefSeqi XP_003066992.1. XM_003066946.1.
UniGenei Cpo.5191.

3D structure databases

ProteinModelPortali C5PCN6.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 9692463.
KEGGi cpw:CPC735_014430.

Phylogenomic databases

eggNOGi COG2355.
KOi K01273.
OrthoDBi EOG7XM371.

Family and domain databases

InterProi IPR000180. Dipep_AS.
IPR008257. Renal_dipep_fam.
[Graphical view ]
PANTHERi PTHR10443. PTHR10443. 1 hit.
Pfami PF01244. Peptidase_M19. 1 hit.
[Graphical view ]
PROSITEi PS00869. RENAL_DIPEPTIDASE_1. 1 hit.
PS51365. RENAL_DIPEPTIDASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C735.

Entry informationi

Entry nameiDPEP2_COCP7
AccessioniPrimary (citable) accession number: C5PCN6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 27, 2011
Last sequence update: September 1, 2009
Last modified: September 3, 2014
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Peptidase families
    Classification of peptidase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi