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C5P6Y2

- C5P6Y2_COCP7

UniProt

C5P6Y2 - C5P6Y2_COCP7

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Protein

Mitogen-activated protein kinase

Gene

CPC735_025180

Organism
Coccidioides posadasii (strain C735) (Valley fever fungus)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.UniRule annotationSAAS annotation

Cofactori

Note: Magnesium.UniRule annotation

Enzyme regulationi

Activated by threonine and tyrosine phosphorylation.UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. MAP kinase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinaseUniRule annotationSAAS annotation, Transferase

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, MagnesiumUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Mitogen-activated protein kinaseUniRule annotation (EC:2.7.11.24UniRule annotation)
Gene namesi
ORF Names:CPC735_025180Imported
OrganismiCoccidioides posadasii (strain C735) (Valley fever fungus)Imported
Taxonomic identifieri222929 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeOnygenalesmitosporic OnygenalesCoccidioides
ProteomesiUP000009084: Unassembled WGS sequence

PTM / Processingi

Keywords - PTMi

PhosphoproteinSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi222929.C5P6Y2.

Structurei

3D structure databases

ProteinModelPortaliC5P6Y2.
SMRiC5P6Y2. Positions 3-343.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.UniRule annotation
Contains 1 protein kinase domain.UniRule annotation
Contains protein kinase domain.SAAS annotation

Phylogenomic databases

eggNOGiCOG0515.
KOiK04441.
OrthoDBiEOG7K3TWD.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR003527. MAP_kinase_CS.
IPR008352. MAPK_p38.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR002290. Ser/Thr_dual-sp_kinase.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
PRINTSiPR01773. P38MAPKINASE.
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS01351. MAPK. 1 hit.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C5P6Y2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAEFVRAQIF GTTFEITTRY TDLQPVGMGA FGLVCSARDQ LTNQAVAVKK
60 70 80 90 100
IMKPFSTPVL AKRTYRELKL LKHLRHENVI SLSDIFISPL EDIYFVTELL
110 120 130 140 150
GTDLHRLLTS RPLEKQFIQY FLYQILRGLK YVHSAGVVHR DLKPSNILIN
160 170 180 190 200
ENCDLKICDF GLARVQDPQM TGYVSTRYYR APEIMLTWQK YDVEVDVWSA
210 220 230 240 250
GCIFAEMLSG RPLFPGKDHV NQFSIITELL GSPPDDVIKT ICSANTLQFV
260 270 280 290 300
QSLPKRERQP LSEKFKGAEP LAVDLLERML VFDPKKRITA AEGLAHEYLA
310 320 330 340 350
PYHDPTDEPV AETQFDWSFN DAELPIDSWK VMMYSEILDY HNVDQDSQGI
360
HGTPLNTEAQ RVPM
Length:364
Mass (Da):41,608
Last modified:September 1, 2009 - v1
Checksum:iCB4A1CFAD2137BF8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ACFW01000025 Genomic DNA. Translation: EER27182.1.
RefSeqiXP_003069327.1. XM_003069281.1.
UniGeneiCpo.2625.

Genome annotation databases

GeneIDi9694822.
KEGGicpw:CPC735_025180.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ACFW01000025 Genomic DNA. Translation: EER27182.1 .
RefSeqi XP_003069327.1. XM_003069281.1.
UniGenei Cpo.2625.

3D structure databases

ProteinModelPortali C5P6Y2.
SMRi C5P6Y2. Positions 3-343.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 222929.C5P6Y2.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 9694822.
KEGGi cpw:CPC735_025180.

Phylogenomic databases

eggNOGi COG0515.
KOi K04441.
OrthoDBi EOG7K3TWD.

Family and domain databases

InterProi IPR011009. Kinase-like_dom.
IPR003527. MAP_kinase_CS.
IPR008352. MAPK_p38.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR002290. Ser/Thr_dual-sp_kinase.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view ]
Pfami PF00069. Pkinase. 1 hit.
[Graphical view ]
PRINTSi PR01773. P38MAPKINASE.
SMARTi SM00220. S_TKc. 1 hit.
[Graphical view ]
SUPFAMi SSF56112. SSF56112. 1 hit.
PROSITEi PS01351. MAPK. 1 hit.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C735Imported.

Entry informationi

Entry nameiC5P6Y2_COCP7
AccessioniPrimary (citable) accession number: C5P6Y2
Entry historyi
Integrated into UniProtKB/TrEMBL: September 1, 2009
Last sequence update: September 1, 2009
Last modified: November 26, 2014
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3