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Protein

Hexokinase

Gene

CPC735_024660

Organism
Coccidioides posadasii (strain C735) (Valley fever fungus)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + D-hexose = ADP + D-hexose 6-phosphate.UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. glucokinase activity Source: UniProtKB-EC

GO - Biological processi

  1. glycolytic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotation, Transferase

Keywords - Biological processi

GlycolysisUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
HexokinaseUniRule annotation (EC:2.7.1.1UniRule annotation)
Gene namesi
ORF Names:CPC735_024660Imported
OrganismiCoccidioides posadasii (strain C735) (Valley fever fungus)Imported
Taxonomic identifieri222929 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeOnygenalesmitosporic OnygenalesCoccidioides
ProteomesiUP000009084 Componenti: Unassembled WGS sequence

Interactioni

Protein-protein interaction databases

STRINGi222929.C5P6T0.

Family & Domainsi

Sequence similaritiesi

Belongs to the hexokinase family.UniRule annotation
Contains 1 hexokinase type-1 domain.UniRule annotation
Contains 1 hexokinase type-2 domain.UniRule annotation

Phylogenomic databases

eggNOGiCOG5026.
KOiK00844.
OrthoDBiEOG79SF68.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR019807. Hexokinase_CS.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.
PROSITEiPS00378. HEXOKINASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C5P6T0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLPQSDQPVI AEAKRIAAEF EYSSADVNRG VKKFLSEMEI GLTGEGSTLS
60 70 80 90 100
QIPSYITCVP DGSEKGVYLA VDLGGTNIRV CSIHLNGDST FDMTQEKAVI
110 120 130 140 150
PRELMVSDSA AELFGFIAEQ IECFLQKHHE ERYGSHTEKR RLGSTAFHDE
160 170 180 190 200
DIFDLGFTFS FPVIQTAINK GNLYRWTKGF DIPDAVGQDV CKLLQDAVDQ
210 220 230 240 250
RNLPVRVSAL INDTVGTLMA RSYCSSGHSK ALIGAIFGTG TNGAYVERLD
260 270 280 290 300
RVKKLNNRGG DLVDASASEM VVNTEWGSFD NPLEVLPNTR HDQELDGISV
310 320 330 340 350
NPGVQMFEKR VSGMFLGEIL RCTILHMNKN PALNLCGGSS AIPKDSILYQ
360 370 380 390 400
HWGIDTKFLS TVEGDSTDDL REVKEELRSD LGIENASTTD CKAIKVLTHA
410 420 430 440 450
IGKRAARLSA VPLAAIIISS GRLGTEDVID IGVDGSLIEF YPGYEKYIRE
460 470 480 490
AWREIPEIGE KGEKKIQIGI AKDGSGVGAA LSALVARQAE KRKQG
Length:495
Mass (Da):54,010
Last modified:August 31, 2009 - v1
Checksum:i73C4C75232FD4E44
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ACFW01000025 Genomic DNA. Translation: EER27130.1.
RefSeqiXP_003069275.1. XM_003069229.1.
UniGeneiCpo.3446.

Genome annotation databases

GeneIDi9694770.
KEGGicpw:CPC735_024660.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ACFW01000025 Genomic DNA. Translation: EER27130.1.
RefSeqiXP_003069275.1. XM_003069229.1.
UniGeneiCpo.3446.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi222929.C5P6T0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi9694770.
KEGGicpw:CPC735_024660.

Phylogenomic databases

eggNOGiCOG5026.
KOiK00844.
OrthoDBiEOG79SF68.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR019807. Hexokinase_CS.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.
PROSITEiPS00378. HEXOKINASES. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C735Imported.

Entry informationi

Entry nameiC5P6T0_COCP7
AccessioniPrimary (citable) accession number: C5P6T0
Entry historyi
Integrated into UniProtKB/TrEMBL: August 31, 2009
Last sequence update: August 31, 2009
Last modified: March 31, 2015
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.