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Protein

Glutamate decarboxylase

Gene

CPC735_011710

Organism
Coccidioides posadasii (strain C735) (Valley fever fungus)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

  1. glutamate decarboxylase activity Source: UniProtKB-EC
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. glutamate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

DecarboxylaseUniRule annotation, Lyase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
ORF Names:CPC735_011710Imported
OrganismiCoccidioides posadasii (strain C735) (Valley fever fungus)Imported
Taxonomic identifieri222929 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeOnygenalesmitosporic OnygenalesCoccidioides
ProteomesiUP000009084: Unassembled WGS sequence

Interactioni

Protein-protein interaction databases

STRINGi222929.C5NZG0.

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0076.
KOiK01580.
OrthoDBiEOG7P2Z22.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 2 hits.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

Sequencei

Sequence statusi: Complete.

C5NZG0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MHLATHVNPE EVIEQLRNDP EESHRRHVFT LNAVATRTAY STRYASSEEI
60 70 80 90 100
PKFRIPQLGA SAEAVYRLLR DELDLDGIPN LNMASFVGTF MEREAQQLLV
110 120 130 140 150
ENISKNLADA DEYPALMDLH ARCISMIANM WHPRPGEQPI GTATTGSSEA
160 170 180 190 200
IQLGGLAMKR RWQEKRRAEG KDTSKPNILM GANAQVALLK FARYFDVEAR
210 220 230 240 250
ILDVSENSHY RLDPNDIKKN VDENTIGIFV ILGSTYTGHY EPVEELSRIL
260 270 280 290 300
DQVQEEHGWD IPIHVDAASG GFIAPFVHAG AGGSKWDFEL SRVHSINVSG
310 320 330 340 350
HKFGLVYVGL GWIIWRDRAY LPKDLIFELH YLGGTEESFG LNFSRPGIQV
360 370 380 390 400
IGQYYNLIRL GFDGYREVME NCLQNARLLS KALERTGWYV CVSDIHRKKG
410 420 430 440 450
DYRFRGVGEI QPHRPGETSA DYNEGLPVVA FRFSEQFKKE YPDVKQEAIS
460 470 480 490 500
LLLRAKQYII PNYPLPPKTD NIEILRVVVR ESMSGDLIDK LISDIVEVTE
510 520 530 540 550
RVMTSEPIDV AVLQSRPTSL ARRHGRLETK LPAKKITKVK AGEKACHPMA

KGGHRSVC
Length:558
Mass (Da):62,988
Last modified:September 1, 2009 - v1
Checksum:i07F70E2F4E555836
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ACFW01000001 Genomic DNA. Translation: EER29853.1.
RefSeqiXP_003071998.1. XM_003071952.1.
UniGeneiCpo.8127.

Genome annotation databases

GeneIDi9697493.
KEGGicpw:CPC735_011710.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ACFW01000001 Genomic DNA. Translation: EER29853.1.
RefSeqiXP_003071998.1. XM_003071952.1.
UniGeneiCpo.8127.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi222929.C5NZG0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi9697493.
KEGGicpw:CPC735_011710.

Phylogenomic databases

eggNOGiCOG0076.
KOiK01580.
OrthoDBiEOG7P2Z22.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 2 hits.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C735Imported.

Entry informationi

Entry nameiC5NZG0_COCP7
AccessioniPrimary (citable) accession number: C5NZG0
Entry historyi
Integrated into UniProtKB/TrEMBL: September 1, 2009
Last sequence update: September 1, 2009
Last modified: February 4, 2015
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.