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Protein

6-phosphofructokinase

Gene

CTRG_05115

Organism
Candida tropicalis (strain ATCC MYA-3404 / T1) (Yeast)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + D-fructose 6-phosphate = ADP + D-fructose 1,6-bisphosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. 6-phosphofructokinase activity Source: UniProtKB-EC
  2. ATP binding Source: UniProtKB-KW

GO - Biological processi

  1. fructose 6-phosphate metabolic process Source: InterPro
  2. glycolytic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotation, Transferase

Keywords - Biological processi

GlycolysisUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

UniPathwayiUPA00109; UER00182.

Names & Taxonomyi

Protein namesi
Recommended name:
6-phosphofructokinaseUniRule annotation (EC:2.7.1.11UniRule annotation)
Alternative name(s):
PhosphohexokinaseUniRule annotation
Gene namesi
ORF Names:CTRG_05115Imported
OrganismiCandida tropicalis (strain ATCC MYA-3404 / T1) (Yeast)Imported
Taxonomic identifieri294747 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeCandida/Lodderomyces cladeCandida
ProteomesiUP000002037: Unassembled WGS sequence

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: InterPro
Complete GO annotation...

Structurei

3D structure databases

ProteinModelPortaliC5MGC2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.UniRule annotation

Phylogenomic databases

KOiK00850.
OrthoDBiEOG7Q5HPV.

Family and domain databases

Gene3Di3.10.180.10. 1 hit.
HAMAPiMF_00339. Phosphofructokinase.
InterProiIPR009161. 6-phosphofructokinase_euk.
IPR029068. Glyas_Bleomycin-R_OHBP_Dase.
IPR022953. Phosphofructokinase.
IPR015912. Phosphofructokinase_CS.
IPR000023. Phosphofructokinase_dom.
[Graphical view]
PfamiPF00365. PFK. 2 hits.
[Graphical view]
PIRSFiPIRSF000533. ATP_PFK_euk. 1 hit.
PRINTSiPR00476. PHFRCTKINASE.
SUPFAMiSSF53784. SSF53784. 2 hits.
SSF54593. SSF54593. 1 hit.
TIGRFAMsiTIGR02478. 6PF1K_euk. 1 hit.
PROSITEiPS00433. PHOSPHOFRUCTOKINASE. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C5MGC2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MISIVNGTST HSLVAGTKET LSQAINFYTN ILGLSVHSEN DDLTYLSNED
60 70 80 90 100
NKMIVKIKLD AKTGLSPSQI HDRREDIISK LNVIDWRSLD TTNVFKVENL
110 120 130 140 150
VALIETLSTY RYTLQITPNE LYPNEVYCVD PLGYIVGFTA CAEPLTLVPP
160 170 180 190 200
LQKANPKFDG ASNLMSKSGS QSRSVEEIKQ VRRNIGVMTS GGDSQGMNAA
210 220 230 240 250
VRAVVRATIF RGCKAFVIKE GYEGLVKGGP EYIKETNWQD VRGYLSEGGT
260 270 280 290 300
NIGTARCMEF KERWGRLLGC RHLIEAGIDG LIVCGGDGSL TGADLFRHEW
310 320 330 340 350
PSLIAELKEK GEITAEQYER HKHLYICGMV GSIDNDMAMT DSTIGGYSAL
360 370 380 390 400
ERICRAVDYI DATASSHSRA FVVEVMGRHC GWLALMAGIA TSADYILIPE
410 420 430 440 450
KPASSKDWKD QMCDIVGKHR AKGKRKTIVI VAEGAITSEL KPITSEEVKD
460 470 480 490 500
VLVDRLGLDT RITVLGHVQR GGTAVAYDRI LATLQGVEAV KAILELTPDV
510 520 530 540 550
PSPLIAIDEN KICCKPLVEA VKITKSVADA IEAQDFDKAM SLRDHEFKEH
560 570 580 590 600
LANFMAMNSA VHEKPTLPVE KRKKIAIVNI GAPAGGMNSA VYAMATYCMS
610 620 630 640 650
RGHTPYAIHN GFAGLARHES VKSMNWIDIE GWNSIGGSEI GTNRQTPEDT
660 670 680 690 700
DIGMIAHYFE KYQFDGLIIV GGFEAFVSLE QLERSRAMYP AFRIPMVLIP
710 720 730 740 750
ATISNNVPGT EYSLGADTCL NSLMEYCDIV KQSASATRGT AFVVDVQGGN
760 770 780 790 800
SGYIATYAAL ISGAQASYVP EEGINLSQLE NDINSLRESF CIEREMTKSG
810 820 830 840 850
KLIIKSSNAS KVLTPHVLAD IINAESHGEF DTKTAIPGHV QQGGLPSPID
860 870 880 890 900
RARGDRFAIK AVQFIEDHAD DLSGLRYSLE FPDDDKKIMN TAAVLGVKSS
910 920 930 940
HLKFTSIRHL YDFETELGRR MPKKIHWSNT REIADRLVGR TRI
Length:943
Mass (Da):103,478
Last modified:July 28, 2009 - v1
Checksum:iF1E85D43802C9B26
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GG692401 Genomic DNA. Translation: EER31385.1.
RefSeqiXP_002550817.1. XM_002550771.1.

Genome annotation databases

GeneIDi8299271.
KEGGictp:CTRG_05115.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GG692401 Genomic DNA. Translation: EER31385.1.
RefSeqiXP_002550817.1. XM_002550771.1.

3D structure databases

ProteinModelPortaliC5MGC2.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi8299271.
KEGGictp:CTRG_05115.

Phylogenomic databases

KOiK00850.
OrthoDBiEOG7Q5HPV.

Enzyme and pathway databases

UniPathwayiUPA00109; UER00182.

Family and domain databases

Gene3Di3.10.180.10. 1 hit.
HAMAPiMF_00339. Phosphofructokinase.
InterProiIPR009161. 6-phosphofructokinase_euk.
IPR029068. Glyas_Bleomycin-R_OHBP_Dase.
IPR022953. Phosphofructokinase.
IPR015912. Phosphofructokinase_CS.
IPR000023. Phosphofructokinase_dom.
[Graphical view]
PfamiPF00365. PFK. 2 hits.
[Graphical view]
PIRSFiPIRSF000533. ATP_PFK_euk. 1 hit.
PRINTSiPR00476. PHFRCTKINASE.
SUPFAMiSSF53784. SSF53784. 2 hits.
SSF54593. SSF54593. 1 hit.
TIGRFAMsiTIGR02478. 6PF1K_euk. 1 hit.
PROSITEiPS00433. PHOSPHOFRUCTOKINASE. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC MYA-3404 / T1Imported.

Entry informationi

Entry nameiC5MGC2_CANTT
AccessioniPrimary (citable) accession number: C5MGC2
Entry historyi
Integrated into UniProtKB/TrEMBL: July 28, 2009
Last sequence update: July 28, 2009
Last modified: February 4, 2015
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.