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Protein

Acetyl-coenzyme A synthetase

Gene

CTRG_04729

Organism
Candida tropicalis (strain ATCC MYA-3404 / T1) (Yeast)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Acetyl-coenzyme A synthetaseUniRule annotation (EC:6.2.1.1UniRule annotation)
Gene namesi
ORF Names:CTRG_04729Imported
OrganismiCandida tropicalis (strain ATCC MYA-3404 / T1) (Yeast)Imported
Taxonomic identifieri294747 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeCandida/Lodderomyces cladeCandida
ProteomesiUP000002037 Componenti: Unassembled WGS sequence

Interactioni

Protein-protein interaction databases

STRINGi294747.XP_002550431.1.

Structurei

3D structure databases

ProteinModelPortaliC5MF86.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP-dependent AMP-binding enzyme family.UniRule annotation

Phylogenomic databases

KOiK01895.
OrthoDBiEOG7M3J82.

Family and domain databases

InterProiIPR011904. Ac_CoA_lig.
IPR025110. AMP-bd_C.
IPR020845. AMP-binding_CS.
IPR000873. AMP-dep_Synth/Lig.
[Graphical view]
PfamiPF00501. AMP-binding. 1 hit.
PF13193. AMP-binding_C. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02188. Ac_CoA_lig_AcsA. 1 hit.
PROSITEiPS00455. AMP_BINDING. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C5MF86-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTTESNNHKV VHEANGVQLR ETPKEFFQRQ PNKGHIQDTE EYKKMYEQSI
60 70 80 90 100
KDPQGFFGPL AKELLSWDSD FHTVKSGTLK NGDAAWFLGG KLNASYNCVD
110 120 130 140 150
RHALANPNKP AIIYEADEEK DSYILTYGDL LREVSKVAGV LHSWGVRKGD
160 170 180 190 200
TVAVYLPMNA QALIAMLAIA RLGAAHSVIF AGFSSGSIKD RVNDASCKAL
210 220 230 240 250
ITCDEGRRGG RTTNIKKLCD EALKQCPTVQ KVLVHRRTGN PDIKLVEGRD
260 270 280 290 300
YYWDEETAKF SGYFPPVAVD SEDPLFLLYT SGSTGTPKGV VHSTAGYLLG
310 320 330 340 350
AALTTKYIFD VHPEDIFFTA GDVGWITGHT YALYGPLLLG VPSVVFEGTP
360 370 380 390 400
AYPDYGRFWQ IVEKHKATHF YVAPTALRLL RKAGEQEIAK YDLSSLRTLG
410 420 430 440 450
SVGEPISPDI WEWYNEFVGK DQCHISDTYW QTESGSHLIA PLAGVIANKP
460 470 480 490 500
GSASYPFFGI DAALIDPVSG VEITGNDVEG VLVVKDHWPS MARTVFNNHV
510 520 530 540 550
KYMDTYMNPY PGYYFTGDGA ARDNDGYYWI RGRVDDVVNV SGHRLSTAEI
560 570 580 590 600
ESALIEDPRV GESAVVGIND DLTGQAVVAY VALKTGDVPD EDALRKELIL
610 620 630 640 650
LVRKEIGPFA APKSVILVQD LPKTRSGKIM RRILRKVSSN EADQLGDITT
660 670
LQNPGSVEGI ISAFSAQFGR K
Length:671
Mass (Da):73,892
Last modified:July 28, 2009 - v1
Checksum:i98CE6E4458B8C1DF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GG692400 Genomic DNA. Translation: EER31946.1.
RefSeqiXP_002550431.1. XM_002550385.1.

Genome annotation databases

GeneIDi8298082.
KEGGictp:CTRG_04729.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GG692400 Genomic DNA. Translation: EER31946.1.
RefSeqiXP_002550431.1. XM_002550385.1.

3D structure databases

ProteinModelPortaliC5MF86.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi294747.XP_002550431.1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi8298082.
KEGGictp:CTRG_04729.

Phylogenomic databases

KOiK01895.
OrthoDBiEOG7M3J82.

Family and domain databases

InterProiIPR011904. Ac_CoA_lig.
IPR025110. AMP-bd_C.
IPR020845. AMP-binding_CS.
IPR000873. AMP-dep_Synth/Lig.
[Graphical view]
PfamiPF00501. AMP-binding. 1 hit.
PF13193. AMP-binding_C. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02188. Ac_CoA_lig_AcsA. 1 hit.
PROSITEiPS00455. AMP_BINDING. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC MYA-3404 / T1Imported.

Entry informationi

Entry nameiC5MF86_CANTT
AccessioniPrimary (citable) accession number: C5MF86
Entry historyi
Integrated into UniProtKB/TrEMBL: July 28, 2009
Last sequence update: July 28, 2009
Last modified: June 24, 2015
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.