Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

2-oxoglutarate dehydrogenase E1 component, mitochondrial

Gene

CTRG_04027

Organism
Candida tropicalis (strain ATCC MYA-3404 / T1) (Yeast)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. oxoglutarate dehydrogenase (succinyl-transferring) activity Source: InterPro
  2. thiamine pyrophosphate binding Source: InterPro

GO - Biological processi

  1. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
2-oxoglutarate dehydrogenase E1 component, mitochondrialImported
Gene namesi
ORF Names:CTRG_04027Imported
OrganismiCandida tropicalis (strain ATCC MYA-3404 / T1) (Yeast)Imported
Taxonomic identifieri294747 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeCandida/Lodderomyces cladeCandida
ProteomesiUP000002037 Componenti: Unassembled WGS sequence

Family & Domainsi

Phylogenomic databases

KOiK00164.
OrthoDBiEOG72G1GM.

Family and domain databases

Gene3Di3.40.50.970. 2 hits.
InterProiIPR011603. 2oxoglutarate_DH_E1.
IPR001017. DH_E1.
IPR029061. THDP-binding.
IPR005475. Transketolase-like_Pyr-bd.
[Graphical view]
PANTHERiPTHR23152. PTHR23152. 1 hit.
PfamiPF00676. E1_dh. 1 hit.
PF02779. Transket_pyr. 1 hit.
[Graphical view]
PIRSFiPIRSF000157. Oxoglu_dh_E1. 1 hit.
SMARTiSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMiSSF52518. SSF52518. 2 hits.
TIGRFAMsiTIGR00239. 2oxo_dh_E1. 1 hit.

Sequencei

Sequence statusi: Complete.

C5MCS6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLTAFRNAVP RAQLLKVNIP KTTYTQLSKR FLATDSFLQG NNSTYVDEMY
60 70 80 90 100
DAWRHDPSSV HASWNAYFKN IENDNVPPSK AFQAPPTIVP TVSGGAAGFY
110 120 130 140 150
PGQSPISEDV VTHLKVQLLV RAYQVRGHQK AKIDPLGISF GDNATVPREL
160 170 180 190 200
TLEYYGFTDK DLDKEITLGP GILHRFTQDG KKSMTLREII DTCEQTYCSS
210 220 230 240 250
YGVEYVHIPS KEKCDWLRDR IEVPQPYKYS PDQKRQILDR LIWATSFEAF
260 270 280 290 300
LSSKFPNDKR FGLEGAEAVV PGMKSLIDTS VEYGVEDVVI GMPHRGRLNM
310 320 330 340 350
LSNVVRKPNE SIFSEFTGSK EFDEGSGDVK YHLGMNYARP TTSGKHVNLS
360 370 380 390 400
IVANPSHLEA EDGVVLGKTR AIQQYKNDIG NFKKAMAVLL HGDAAFAAQG
410 420 430 440 450
VVYETMGFAS LPAYSTGGTI HVIVNNQIGF TTDPRFARST LYPSDIAKSI
460 470 480 490 500
DAPIFHVNAD DVEACTFVFN LAAEWRATFH TDCIIDVVGY RKYGHNETDQ
510 520 530 540 550
PSFTQPLMYQ EIAKKKSVID IYEKQLINEG TFTAEDIQEH KKWVWDVLED
560 570 580 590 600
NFKKAKDYKP TSREWLTTPW EDFKSPRELA TEVLPHLPTA VDEGILKKIG
610 620 630 640 650
KAISETPEGF EVHRNLKRIL NARKKSVETG EGIDYATGEA LAYGSLALEG
660 670 680 690 700
YHVRVSGQDV ERGTFSQRHA VLHDQNSEST WTPLSNLAED QGAFNISNSS
710 720 730 740 750
LSEYGVLGFE YGYSLTSPDA LVEWEAQFGD FANTAQVVID QFVAGAESKW
760 770 780 790 800
KQRSGVVLSL PHGYDGQGPE HSSARIERYL QLCNEDQRYF PSPEKLERQH
810 820 830 840 850
QDCNMQVAYP TTPANIFHLL RRQMHREFRK PLIVIFSKSL LRHPLARSNL
860 870 880 890 900
SEFTGDSHFQ WIIEDVLGEK SEVKRVVLLS GQVYAALHKK RAALEDKTTA
910 920 930 940 950
FIKVEQLHPF PYAQLRDALN EYPNIEDLVW TQEEPLNMGA YNYVAPRIEA
960 970 980 990
VLQETENYKD LKLRYAGRDP SASVAAGSKS MHVAEEEEII AQTFQ
Length:995
Mass (Da):112,129
Last modified:July 28, 2009 - v1
Checksum:i0324A1993F53321E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GG692399 Genomic DNA. Translation: EER32356.1.
RefSeqiXP_002549730.1. XM_002549684.1.

Genome annotation databases

GeneIDi8297005.
KEGGictp:CTRG_04027.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GG692399 Genomic DNA. Translation: EER32356.1.
RefSeqiXP_002549730.1. XM_002549684.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi8297005.
KEGGictp:CTRG_04027.

Phylogenomic databases

KOiK00164.
OrthoDBiEOG72G1GM.

Family and domain databases

Gene3Di3.40.50.970. 2 hits.
InterProiIPR011603. 2oxoglutarate_DH_E1.
IPR001017. DH_E1.
IPR029061. THDP-binding.
IPR005475. Transketolase-like_Pyr-bd.
[Graphical view]
PANTHERiPTHR23152. PTHR23152. 1 hit.
PfamiPF00676. E1_dh. 1 hit.
PF02779. Transket_pyr. 1 hit.
[Graphical view]
PIRSFiPIRSF000157. Oxoglu_dh_E1. 1 hit.
SMARTiSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMiSSF52518. SSF52518. 2 hits.
TIGRFAMsiTIGR00239. 2oxo_dh_E1. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC MYA-3404 / T1Imported.

Entry informationi

Entry nameiC5MCS6_CANTT
AccessioniPrimary (citable) accession number: C5MCS6
Entry historyi
Integrated into UniProtKB/TrEMBL: July 28, 2009
Last sequence update: July 28, 2009
Last modified: January 7, 2015
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.