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Protein

Hexokinase

Gene

CTRG_00414

Organism
Candida tropicalis (strain ATCC MYA-3404 / T1) (Yeast)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + D-hexose = ADP + D-hexose 6-phosphate.UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. kinase activity Source: UniProtKB-KW
  3. phosphotransferase activity, alcohol group as acceptor Source: InterPro

GO - Biological processi

  1. glycolytic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotation, Transferase

Keywords - Biological processi

GlycolysisUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
HexokinaseUniRule annotation (EC:2.7.1.1UniRule annotation)
Gene namesi
ORF Names:CTRG_00414Imported
OrganismiCandida tropicalis (strain ATCC MYA-3404 / T1) (Yeast)Imported
Taxonomic identifieri294747 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeCandida/Lodderomyces cladeCandida
ProteomesiUP000002037: Unassembled WGS sequence

Family & Domainsi

Sequence similaritiesi

Belongs to the hexokinase family.UniRule annotation
Contains 1 hexokinase type-1 domain.UniRule annotation
Contains 1 hexokinase type-2 domain.UniRule annotation

Phylogenomic databases

KOiK00844.
OrthoDBiEOG79SF68.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.

Sequencei

Sequence statusi: Complete.

C5M2X5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVHLGPKPAQ PRKGTFTDVP SQLLEAIKPF EKEFTISGET LRAIVAHFIK
60 70 80 90 100
ELNRGLSKQG GNIPMIPGWV MEYPTGKETG NYLAIDLGGT NLRVVLVKLG
110 120 130 140 150
GNRDFDTTQS KFALPSHMRT ATKDELWDFI AKCLKQVVDE VFPEGVTQPI
160 170 180 190 200
PLGFTFSYPA SQDRINEGVL QRWTKGWAID GIEGHDVVPM LQSAVKKVGV
210 220 230 240 250
PINVVALIND TTGTLVASLY TDPETKMGVI FGTGVNGAYY DVVGEIPKLE
260 270 280 290 300
GRCGADIPPT SLMAINCEYG SFDNEHFILP RTKYDIQIDA ESPKPGQQTF
310 320 330 340 350
EKMNSGYYLG ELLRLILLEL ADEKKLIFKG QNIDKLRKPY VMDTSFPSRI
360 370 380 390 400
ELDPFENLSD VADIFQDELG IQTTEPERKI IRRLSELIGE RSARLSVCGI
410 420 430 440 450
AAICQKRGYE TAHIAADGSV FNRYPGFKER AAKALRDIYQ WPATQKDPIV
460 470 480
IVAAEDGSGV GAAIIAALTE KRLKEGKSVG VIA
Length:483
Mass (Da):53,206
Last modified:July 28, 2009 - v1
Checksum:i1E4BCEDDA30C0130
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GG692395 Genomic DNA. Translation: EER35675.1.
RefSeqiXP_002545633.1. XM_002545587.1.

Genome annotation databases

GeneIDi8296095.
KEGGictp:CTRG_00414.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GG692395 Genomic DNA. Translation: EER35675.1.
RefSeqiXP_002545633.1. XM_002545587.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi8296095.
KEGGictp:CTRG_00414.

Phylogenomic databases

KOiK00844.
OrthoDBiEOG79SF68.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC MYA-3404 / T1Imported.

Entry informationi

Entry nameiC5M2X5_CANTT
AccessioniPrimary (citable) accession number: C5M2X5
Entry historyi
Integrated into UniProtKB/TrEMBL: July 28, 2009
Last sequence update: July 28, 2009
Last modified: March 4, 2015
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.