C5J6Z8 (C5J6Z8_MYCCR) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Protein translocase subunit SecA HAMAP-Rule MF_01382 RuleBase RU003874

Gene names

Name:	secA HAMAP-Rule MF_01382
Ordered Locus Names:	MCJ_005620

Organism

Mycoplasma conjunctivae (strain ATCC 25834 / HRC/581 / NCTC 10147) [Complete proteome] [HAMAP]

Taxonomic identifier

572263 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Tenericutes › Mollicutes › Mycoplasmatales › Mycoplasmataceae › Mycoplasma › Mycoplasma conjunctivae

Protein attributes

Sequence length	995 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane By similarity. HAMAP-Rule MF_01382
Subunit structure	Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved By similarity. HAMAP-Rule MF_01382
Subcellular location	Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note: Distribution is 50-50 By similarity. HAMAP-Rule MF_01382
Sequence similarities	Belongs to the SecA family. HAMAP-Rule MF_01382 RuleBase RU003874

Ontologies

Keywords
Biological process	Protein transport Translocation HAMAP-Rule MF_01382 RuleBase RU003874 Transport
Cellular component	Cell membrane HAMAP-Rule MF_01382 Cytoplasm HAMAP-Rule MF_01382 Membrane
Ligand	ATP-binding HAMAP-Rule MF_01382 RuleBase RU003874 Nucleotide-binding
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	intracellular protein transmembrane transport Inferred from electronic annotation. Source: HAMAP protein import Inferred from electronic annotation. Source: InterPro protein targeting Inferred from electronic annotation. Source: HAMAP
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ATP binding Inferred from electronic annotation. Source: HAMAP helicase activity Inferred from electronic annotation. Source: InterPro nucleic acid binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Nucleotide binding	98 – 105	8	ATP By similarity HAMAP-Rule MF_01382

Sequences

	Sequence		Length	Mass (Da)
	C5J6Z8 [UniParc]. Last modified July 28, 2009. Version 1. Checksum: A57B32E61B3DF7E2	FASTA	995	114,425
	10 20 30 40 50 60 MKSATNFFTM SSEMRLAYRL LKQINNKRAY YAAMSDDQLA NQTYELKLRL SRGEKHEDIR 70 80 90 100 110 120 VDAFAVAREA TKRVLNKYPY DVQILGGLIL DMGSVAEMKT GEGKTIAAIA PVYLNALKGE 130 140 150 160 170 180 GVIVSTVNEY LAERDAADNG KVFNFLGLSV GVNRAGMDSR TKKIMYSADI TYSIHSELGF 190 200 210 220 230 240 DYLRDNMVFN KEEKVQRSLN FCLLDEIDSI LIDEAKTPLI ISGGQQLNPG DYYSANQFVQ 250 260 270 280 290 300 TLVDDDFYVD EETKGIKLND QGIDKANAFF KTKNLYEIGN SELVHRIQNA LRANKVMKKD 310 320 330 340 350 360 VEYIVLDDKI ELVDQFTGRI MQGRSYSEGL QQALQAKENL EIEPETKTLA TITYQNFFRL 370 380 390 400 410 420 FKKLSGMTGT AKTEEQEFID VYNMRVNVIP TNKPIARLDD SDLIFGTLHA KNQAIIAEVE 430 440 450 460 470 480 RVHKKGQPIL IGTSQVADSE TLSDMLRERG LSHTVLNAKQ NEYEAEIISK AGVKNAITIA 490 500 510 520 530 540 TNMAGRGTDI KLDSEVIDLG GLYILGTDKA ESRRIDNQLR GRSGRQGDIG YSRFYISIED 550 560 570 580 590 600 PLLRRFSNFE QIQQVYGSDK SLEPIKGKFI KKTLINAQKK IEGFNFDMRK SVLSYDDVIR 610 620 630 640 650 660 QQRDLIYTQR NILLESDNFD HYIKRMIIRT VDIILGFDFI SLPNQEIHYT NLVNYLNDNL 670 680 690 700 710 720 SRITHYDFSE LKLYNYPYDE VAKVIIEQLE TIYFEQLQPQ LKENLGETYY ENERYIILSS 730 740 750 760 770 780 LDHYWQSHID TIDKLRSSAN LVQYSQKNPY QIFIEESTKK FNILISESAN QAIVSLFNNE 790 800 810 820 830 840 NARKIVYNEY TLSNGQILSF AEDTPIELIE QIIKNNEERI EHEKQLAIYN SDEFIYKQLE 850 860 870 880 890 900 DLNIKLVQDD LESDFQIFAL SSGKQIQIKR SFSLTDKRTI LVSMNEDELK NQLENDNQNS 910 920 930 940 950 960 SLDSQQLSSE LSQPEDLSNQ NSFTEKSVYE IEQENLANFA NPNFSEVNEN NLQAPVEQNF 970 980 990 DDEIETFFNQ NEKEKQQNSY KNIDNLSDLD NRDIF

References

[1]

"The Mycoplasma conjunctivae genome sequencing, annotation and analysis." Calderon-Copete S.P., Wigger G., Wunderlin C., Schmidheini T., Frey J., Quail M.A., Falquet L. BMC Bioinformatics 10:S7-S7(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 25834 / HRC/581 / NCTC 10147.

Cross-references

Sequence databases
EMBL GenBank DDBJ	FM864216 Genomic DNA. Translation: CAT05261.1.
RefSeq	YP_002961064.1. NC_012806.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	45361.MCJ_005620.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAT05261; CAT05261; MCJ_005620.
GeneID	7989356.
KEGG	mco:MCJ_005620.
PATRIC	20007327. VBIMycCon56923_0539.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HOG000218169.
KO	K03070.
ProtClustDB	PRK12903.
Family and domain databases
Gene3D	1.10.3060.10. 1 hit. 3.90.1440.10. 1 hit.
HAMAP	MF_01382. SecA.
InterPro	IPR001650. Helicase_C. IPR000185. SecA. IPR020937. SecA_CS. IPR011115. SecA_DEAD. IPR014018. SecA_motor_DEAD. IPR011130. SecA_preprotein_X-link_dom. IPR011116. SecA_Wing/Scaffold. [Graphical view]
Pfam	PF00271. Helicase_C. 1 hit. PF07517. SecA_DEAD. 1 hit. PF01043. SecA_PP_bind. 1 hit. PF07516. SecA_SW. 1 hit. [Graphical view]
PRINTS	PR00906. SECA.
SMART	SM00957. SecA_DEAD. 1 hit. SM00958. SecA_PP_bind. 1 hit. [Graphical view]
SUPFAM	SSF81767. SecA_PP_bd. 1 hit. SSF81886. SecA_SW. 1 hit.
TIGRFAMs	TIGR00963. secA. 1 hit.
PROSITE	PS01312. SECA. 1 hit. PS51196. SECA_MOTOR_DEAD. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

C5J6Z8_MYCCR

Accession

Primary (citable) accession number: C5J6Z8

Entry history

Integrated into UniProtKB/TrEMBL:	July 28, 2009
Last sequence update:	July 28, 2009
Last modified:	May 1, 2013
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)