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C5H8V4

- C5H8V4_MOUSE

UniProt

C5H8V4 - C5H8V4_MOUSE

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Protein
Submitted name: Ferroportin1 isoform FPN1B1
Gene
Slc40a1
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 4 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. iron ion transmembrane transporter activity Source: MGI

GO - Biological processi

  1. cellular iron ion homeostasis Source: Ensembl
  2. endothelium development Source: MGI
  3. iron ion transport Source: MGI
  4. lymphocyte homeostasis Source: MGI
  5. multicellular organismal iron ion homeostasis Source: MGI
  6. negative regulation of apoptotic process Source: MGI
  7. regulation of transcription from RNA polymerase II promoter in response to iron Source: MGI
  8. spleen development Source: MGI
  9. spleen trabecula formation Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Ferroportin1 isoform FPN1B1Imported
Submitted name:
Ferroportin1 isoform FPN1B2Imported
Submitted name:
Ferroportin1 isoform FPN1B3Imported
Gene namesi
Name:Slc40a1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1315204. Slc40a1.

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: InterPro
  2. multivesicular body Source: MGI
  3. plasma membrane Source: MGI
  4. synaptic vesicle Source: MGI
Complete GO annotation...

Expressioni

Gene expression databases

GenevestigatoriC5H8V4.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000027137.

Family & Domainsi

Family and domain databases

InterProiIPR009716. Ferroportin-1.
[Graphical view]
PfamiPF06963. FPN1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

C5H8V4-1 [UniParc]FASTAAdd to Basket

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MTKARDQTHQ EGCCGSLANY LTSAKFLLYL GHSLSTWGDR MWHFAVSVFL   50
VELYGNSLLL TAVYGLVVAG 70
Length:70
Mass (Da):7,713
Last modified:July 28, 2009 - v1
Checksum:iF933CD44683CD4EE
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei70 – 701Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FJ207421 mRNA. Translation: ACO54854.1.
FJ207422 mRNA. Translation: ACO54855.1.
FJ207423 mRNA. Translation: ACO54856.1.
UniGeneiMm.28756.

Genome annotation databases

UCSCiuc011wkh.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FJ207421 mRNA. Translation: ACO54854.1 .
FJ207422 mRNA. Translation: ACO54855.1 .
FJ207423 mRNA. Translation: ACO54856.1 .
UniGenei Mm.28756.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 10090.ENSMUSP00000027137.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

UCSCi uc011wkh.1. mouse.

Organism-specific databases

MGIi MGI:1315204. Slc40a1.

Miscellaneous databases

NextBioi 35548218.
SOURCEi Search...

Gene expression databases

Genevestigatori C5H8V4.

Family and domain databases

InterProi IPR009716. Ferroportin-1.
[Graphical view ]
Pfami PF06963. FPN1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Zhang D.-L., Rouault T.A.
    Submitted (SEP-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BALB/cImported.
    Tissue: SpleenImported.
  2. "A ferroportin transcript that lacks an iron-responsive element enables duodenal and erythroid precursor cells to evade translational repression."
    Zhang D.L., Hughes R.M., Ollivierre-Wilson H., Ghosh M.C., Rouault T.A.
    Cell Metab. 9:461-473(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BALB/cImported.
    Tissue: SpleenImported.

Entry informationi

Entry nameiC5H8V4_MOUSE
AccessioniPrimary (citable) accession number: C5H8V4
Entry historyi
Integrated into UniProtKB/TrEMBL: July 28, 2009
Last sequence update: July 28, 2009
Last modified: June 11, 2014
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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