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Protein
Submitted name:

Ferroportin1 isoform FPN1B1

Gene

Slc40a1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • iron ion transmembrane transporter activity Source: MGI

GO - Biological processi

  • cellular iron ion homeostasis Source: MGI
  • endothelium development Source: MGI
  • iron ion homeostasis Source: MGI
  • iron ion transmembrane transport Source: MGI
  • iron ion transport Source: MGI
  • lymphocyte homeostasis Source: MGI
  • multicellular organismal iron ion homeostasis Source: MGI
  • negative regulation of apoptotic process Source: MGI
  • positive regulation of transcription from RNA polymerase II promoter Source: MGI
  • regulation of transcription from RNA polymerase II promoter in response to iron Source: MGI
  • spleen development Source: MGI
  • spleen trabecula formation Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Ferroportin1 isoform FPN1B1Imported
Submitted name:
Ferroportin1 isoform FPN1B2Imported
Submitted name:
Ferroportin1 isoform FPN1B3Imported
Submitted name:
Solute carrier family 40 member 1Imported
Gene namesi
Name:Slc40a1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589 Componenti: Chromosome 1

Organism-specific databases

MGIiMGI:1315204. Slc40a1.

Subcellular locationi

GO - Cellular componenti

  • basolateral plasma membrane Source: MGI
  • integral component of membrane Source: InterPro
  • intracellular Source: MGI
  • multivesicular body Source: MGI
  • plasma membrane Source: MGI
  • synaptic vesicle Source: MGI
Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000027137.

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00390000015143.

Family and domain databases

InterProiIPR009716. Ferroportin-1.
[Graphical view]
PfamiPF06963. FPN1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

C5H8V4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTKARDQTHQ EGCCGSLANY LTSAKFLLYL GHSLSTWGDR MWHFAVSVFL
60 70
VELYGNSLLL TAVYGLVVAG
Length:70
Mass (Da):7,713
Last modified:July 28, 2009 - v1
Checksum:iF933CD44683CD4EE
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei70 – 701Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC123557 Genomic DNA. No translation available.
FJ207421 mRNA. Translation: ACO54854.1.
FJ207422 mRNA. Translation: ACO54855.1.
FJ207423 mRNA. Translation: ACO54856.1.
UniGeneiMm.28756.

Genome annotation databases

EnsembliENSMUST00000186804; ENSMUSP00000140969; ENSMUSG00000025993.
ENSMUST00000187406; ENSMUSP00000140734; ENSMUSG00000025993.
ENSMUST00000187420; ENSMUSP00000140549; ENSMUSG00000025993.
UCSCiuc011wkh.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC123557 Genomic DNA. No translation available.
FJ207421 mRNA. Translation: ACO54854.1.
FJ207422 mRNA. Translation: ACO54855.1.
FJ207423 mRNA. Translation: ACO54856.1.
UniGeneiMm.28756.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000027137.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000186804; ENSMUSP00000140969; ENSMUSG00000025993.
ENSMUST00000187406; ENSMUSP00000140734; ENSMUSG00000025993.
ENSMUST00000187420; ENSMUSP00000140549; ENSMUSG00000025993.
UCSCiuc011wkh.1. mouse.

Organism-specific databases

MGIiMGI:1315204. Slc40a1.

Phylogenomic databases

GeneTreeiENSGT00390000015143.

Miscellaneous databases

NextBioi35548218.
SOURCEiSearch...

Family and domain databases

InterProiIPR009716. Ferroportin-1.
[Graphical view]
PfamiPF06963. FPN1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Zhang D.-L., Rouault T.A.
    Submitted (SEP-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BALB/cImported.
    Tissue: SpleenImported.
  2. "A ferroportin transcript that lacks an iron-responsive element enables duodenal and erythroid precursor cells to evade translational repression."
    Zhang D.L., Hughes R.M., Ollivierre-Wilson H., Ghosh M.C., Rouault T.A.
    Cell Metab. 9:461-473(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BALB/cImported.
    Tissue: SpleenImported.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  4. Ensembl
    Submitted (SEP-2014) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiC5H8V4_MOUSE
AccessioniPrimary (citable) accession number: C5H8V4
Entry historyi
Integrated into UniProtKB/TrEMBL: July 28, 2009
Last sequence update: July 28, 2009
Last modified: June 24, 2015
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.