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C5H8V4

- C5H8V4_MOUSE

UniProt

C5H8V4 - C5H8V4_MOUSE

Protein
Submitted name:

Ferroportin1 isoform FPN1B1

Gene

Slc40a1

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 4 out of 5- Experimental evidence at transcript leveli
  1. Functioni

    GO - Molecular functioni

    1. iron ion transmembrane transporter activity Source: MGI

    GO - Biological processi

    1. cellular iron ion homeostasis Source: Ensembl
    2. endothelium development Source: MGI
    3. iron ion transport Source: MGI
    4. lymphocyte homeostasis Source: MGI
    5. multicellular organismal iron ion homeostasis Source: MGI
    6. negative regulation of apoptotic process Source: MGI
    7. regulation of transcription from RNA polymerase II promoter in response to iron Source: MGI
    8. spleen development Source: MGI
    9. spleen trabecula formation Source: MGI

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Ferroportin1 isoform FPN1B1Imported
    Submitted name:
    Ferroportin1 isoform FPN1B2Imported
    Submitted name:
    Ferroportin1 isoform FPN1B3Imported
    Gene namesi
    Name:Slc40a1Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

    Organism-specific databases

    MGIiMGI:1315204. Slc40a1.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: InterPro
    2. multivesicular body Source: MGI
    3. plasma membrane Source: MGI
    4. synaptic vesicle Source: MGI

    Expressioni

    Gene expression databases

    GenevestigatoriC5H8V4.

    Interactioni

    Protein-protein interaction databases

    STRINGi10090.ENSMUSP00000027137.

    Family & Domainsi

    Family and domain databases

    InterProiIPR009716. Ferroportin-1.
    [Graphical view]
    PfamiPF06963. FPN1. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    C5H8V4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTKARDQTHQ EGCCGSLANY LTSAKFLLYL GHSLSTWGDR MWHFAVSVFL   50
    VELYGNSLLL TAVYGLVVAG 70
    Length:70
    Mass (Da):7,713
    Last modified:July 28, 2009 - v1
    Checksum:iF933CD44683CD4EE
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei70 – 701Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FJ207421 mRNA. Translation: ACO54854.1.
    FJ207422 mRNA. Translation: ACO54855.1.
    FJ207423 mRNA. Translation: ACO54856.1.
    UniGeneiMm.28756.

    Genome annotation databases

    UCSCiuc011wkh.1. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    FJ207421 mRNA. Translation: ACO54854.1 .
    FJ207422 mRNA. Translation: ACO54855.1 .
    FJ207423 mRNA. Translation: ACO54856.1 .
    UniGenei Mm.28756.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 10090.ENSMUSP00000027137.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    UCSCi uc011wkh.1. mouse.

    Organism-specific databases

    MGIi MGI:1315204. Slc40a1.

    Miscellaneous databases

    NextBioi 35548218.
    SOURCEi Search...

    Gene expression databases

    Genevestigatori C5H8V4.

    Family and domain databases

    InterProi IPR009716. Ferroportin-1.
    [Graphical view ]
    Pfami PF06963. FPN1. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Zhang D.-L., Rouault T.A.
      Submitted (SEP-2008) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: BALB/cImported.
      Tissue: SpleenImported.
    2. "A ferroportin transcript that lacks an iron-responsive element enables duodenal and erythroid precursor cells to evade translational repression."
      Zhang D.L., Hughes R.M., Ollivierre-Wilson H., Ghosh M.C., Rouault T.A.
      Cell Metab. 9:461-473(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: BALB/cImported.
      Tissue: SpleenImported.

    Entry informationi

    Entry nameiC5H8V4_MOUSE
    AccessioniPrimary (citable) accession number: C5H8V4
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 28, 2009
    Last sequence update: July 28, 2009
    Last modified: October 1, 2014
    This is version 29 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)