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C5H8V4

- C5H8V4_MOUSE

UniProt

C5H8V4 - C5H8V4_MOUSE

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Protein
Submitted name:

Ferroportin1 isoform FPN1B1

Gene

Slc40a1

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 4 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. iron ion transmembrane transporter activity Source: MGI

GO - Biological processi

  1. cellular iron ion homeostasis Source: MGI
  2. endothelium development Source: MGI
  3. iron ion transmembrane transport Source: MGI
  4. iron ion transport Source: MGI
  5. lymphocyte homeostasis Source: MGI
  6. multicellular organismal iron ion homeostasis Source: MGI
  7. negative regulation of apoptotic process Source: MGI
  8. regulation of transcription from RNA polymerase II promoter in response to iron Source: MGI
  9. spleen development Source: MGI
  10. spleen trabecula formation Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Ferroportin1 isoform FPN1B1Imported
Submitted name:
Ferroportin1 isoform FPN1B2Imported
Submitted name:
Ferroportin1 isoform FPN1B3Imported
Submitted name:
Solute carrier family 40 member 1Imported
Gene namesi
Name:Slc40a1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 1

Organism-specific databases

MGIiMGI:1315204. Slc40a1.

Subcellular locationi

GO - Cellular componenti

  1. basolateral plasma membrane Source: Ensembl
  2. integral component of membrane Source: InterPro
  3. multivesicular body Source: MGI
  4. plasma membrane Source: MGI
  5. synaptic vesicle Source: MGI
Complete GO annotation...

Expressioni

Gene expression databases

GenevestigatoriC5H8V4.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000027137.

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00390000015143.

Family and domain databases

InterProiIPR009716. Ferroportin-1.
[Graphical view]
PfamiPF06963. FPN1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

C5H8V4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTKARDQTHQ EGCCGSLANY LTSAKFLLYL GHSLSTWGDR MWHFAVSVFL
60 70
VELYGNSLLL TAVYGLVVAG
Length:70
Mass (Da):7,713
Last modified:July 28, 2009 - v1
Checksum:iF933CD44683CD4EE
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei70 – 701Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC123557 Genomic DNA. No translation available.
FJ207421 mRNA. Translation: ACO54854.1.
FJ207422 mRNA. Translation: ACO54855.1.
FJ207423 mRNA. Translation: ACO54856.1.
UniGeneiMm.28756.

Genome annotation databases

EnsembliENSMUST00000186804; ENSMUSP00000140969; ENSMUSG00000025993.
ENSMUST00000187406; ENSMUSP00000140734; ENSMUSG00000025993.
ENSMUST00000187420; ENSMUSP00000140549; ENSMUSG00000025993.
UCSCiuc011wkh.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC123557 Genomic DNA. No translation available.
FJ207421 mRNA. Translation: ACO54854.1 .
FJ207422 mRNA. Translation: ACO54855.1 .
FJ207423 mRNA. Translation: ACO54856.1 .
UniGenei Mm.28756.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 10090.ENSMUSP00000027137.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000186804 ; ENSMUSP00000140969 ; ENSMUSG00000025993 .
ENSMUST00000187406 ; ENSMUSP00000140734 ; ENSMUSG00000025993 .
ENSMUST00000187420 ; ENSMUSP00000140549 ; ENSMUSG00000025993 .
UCSCi uc011wkh.1. mouse.

Organism-specific databases

MGIi MGI:1315204. Slc40a1.

Phylogenomic databases

GeneTreei ENSGT00390000015143.

Miscellaneous databases

NextBioi 35548218.
SOURCEi Search...

Gene expression databases

Genevestigatori C5H8V4.

Family and domain databases

InterProi IPR009716. Ferroportin-1.
[Graphical view ]
Pfami PF06963. FPN1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Zhang D.-L., Rouault T.A.
    Submitted (SEP-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BALB/cImported.
    Tissue: SpleenImported.
  2. "A ferroportin transcript that lacks an iron-responsive element enables duodenal and erythroid precursor cells to evade translational repression."
    Zhang D.L., Hughes R.M., Ollivierre-Wilson H., Ghosh M.C., Rouault T.A.
    Cell Metab. 9:461-473(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BALB/cImported.
    Tissue: SpleenImported.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  4. Ensembl
    Submitted (SEP-2014) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiC5H8V4_MOUSE
AccessioniPrimary (citable) accession number: C5H8V4
Entry historyi
Integrated into UniProtKB/TrEMBL: July 28, 2009
Last sequence update: July 28, 2009
Last modified: October 29, 2014
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3