Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

C5FW30

- SPCA_ARTOC

UniProt

C5FW30 - SPCA_ARTOC

Protein

Carboxypeptidase S1 homolog A

Gene

SCPA

Organism
Arthroderma otae (strain ATCC MYA-4605 / CBS 113480) (Microsporum canis)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 30 (01 Oct 2014)
      Sequence version 1 (28 Jul 2009)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Extracellular serine carboxypeptidase that contributes to pathogenicity.By similarity

    Catalytic activityi

    Preferential release of a C-terminal arginine or lysine residue.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei238 – 2381PROSITE-ProRule annotation
    Active sitei458 – 4581PROSITE-ProRule annotation
    Binding sitei461 – 4611SubstrateBy similarity
    Active sitei515 – 5151PROSITE-ProRule annotation
    Binding sitei516 – 5161SubstrateBy similarity

    GO - Molecular functioni

    1. serine-type carboxypeptidase activity Source: InterPro

    GO - Biological processi

    1. pathogenesis Source: UniProtKB-KW

    Keywords - Molecular functioni

    Carboxypeptidase, Hydrolase, Protease

    Keywords - Biological processi

    Virulence

    Protein family/group databases

    MEROPSiS10.016.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Carboxypeptidase S1 homolog A (EC:3.4.16.6)
    Alternative name(s):
    Serine carboxypeptidase A
    Short name:
    SPCA
    Gene namesi
    Name:SCPA
    ORF Names:MCYG_06933
    OrganismiArthroderma otae (strain ATCC MYA-4605 / CBS 113480) (Microsporum canis)
    Taxonomic identifieri554155 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeOnygenalesArthrodermataceaeArthroderma
    ProteomesiUP000002035: Unassembled WGS sequence

    Subcellular locationi

    GO - Cellular componenti

    1. anchored component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 1919Sequence AnalysisAdd
    BLAST
    Chaini20 – 625606Carboxypeptidase S1 homolog APRO_0000384113Add
    BLAST
    Propeptidei626 – 65126Removed in mature formSequence AnalysisPRO_0000384114Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Disulfide bondi50 ↔ 121By similarity
    Glycosylationi77 – 771N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi125 – 1251N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi128 – 1281N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi161 – 1611N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi184 – 1841N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi202 – 2021N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi260 – 2601N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi299 – 2991N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi308 – 3081N-linked (GlcNAc...)Sequence Analysis
    Disulfide bondi325 ↔ 361By similarity
    Disulfide bondi332 ↔ 354By similarity
    Glycosylationi347 – 3471N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi410 – 4101N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi474 – 4741N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi504 – 5041N-linked (GlcNAc...)Sequence Analysis
    Lipidationi625 – 6251GPI-anchor amidated serineSequence Analysis

    Keywords - PTMi

    Disulfide bond, Glycoprotein, GPI-anchor, Lipoprotein

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the peptidase S10 family.Curated

    Keywords - Domaini

    Signal

    Phylogenomic databases

    OrthoDBiEOG7FV40C.

    Family and domain databases

    Gene3Di3.40.50.1820. 1 hit.
    InterProiIPR029058. AB_hydrolase.
    IPR001563. Peptidase_S10.
    IPR018202. Peptidase_S10_AS.
    [Graphical view]
    PANTHERiPTHR11802. PTHR11802. 1 hit.
    PfamiPF00450. Peptidase_S10. 1 hit.
    [Graphical view]
    PRINTSiPR00724. CRBOXYPTASEC.
    SUPFAMiSSF53474. SSF53474. 2 hits.
    PROSITEiPS00131. CARBOXYPEPT_SER_SER. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    C5FW30-1 [UniParc]FASTAAdd to Basket

    « Hide

    MHLATGLAVA LPFIGAASAQ YFPPPVEGVT VVESKFDKNV KITYKENDIC    50
    ETTEGVRSFT GHVHLPPNNN DFGVNQNYSI NTFFWFFEAR EDPKNAPLSI 100
    WLNGGPGSSS MIGLFQENGP CMVNNDSNST TNNPYSWNNK VNMLYIDQPN 150
    QVGFSYDVPT NVTVNPINDE VTVADFSNGV PEQNNTLLVG TLGSQNPYAT 200
    ANNTQNAARS IWHFAQVWFQ EFPEYKPNND KVSIWTESYG GRYGPAFTSY 250
    FQEQNEKIKN HTITEEGEMH ILHLDTVGII NGCVDLMEQA TSYPDFAYNN 300
    TYGIKAYNQS QYDSMINEFY RTGGCRDQLI HCRDVAAESD PHFYSHNETV 350
    NKICNDAGDF CGQKLEDAFE SANLGFYDIA HPLNDPFPPQ FYKGYLSQAH 400
    VLADMGMPVN FSQASDAVWK AFHTVGDYGR GDVRGYIDDL AYLLENGIKV 450
    ALVYGDRDYI CNWFGGEKVS LALNYTGTEN FHKAGYTDVK VNSQVGGQVR 500
    QYGNFSFTRV YEAGHEVPAY QPEVSLEIFH RIMFNKDIAT GEIDIAQKPD 550
    YSTTGTADTF HIKNDIPPEP EPTCYVLSMG RTCSEEQVKA VKDGTAVVEN 600
    YIVKSPAGKK QGPPPTSTSP PSPTSSSEGS VKEFSVSVLG VSVLAAITFF 650
    L 651
    Length:651
    Mass (Da):72,198
    Last modified:July 28, 2009 - v1
    Checksum:i074F1DA49231EAE6
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DS995706 Genomic DNA. Translation: EEQ34114.1.
    RefSeqiXP_002844969.1. XM_002844923.1.

    Genome annotation databases

    GeneIDi9228194.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DS995706 Genomic DNA. Translation: EEQ34114.1 .
    RefSeqi XP_002844969.1. XM_002844923.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    MEROPSi S10.016.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 9228194.

    Phylogenomic databases

    OrthoDBi EOG7FV40C.

    Family and domain databases

    Gene3Di 3.40.50.1820. 1 hit.
    InterProi IPR029058. AB_hydrolase.
    IPR001563. Peptidase_S10.
    IPR018202. Peptidase_S10_AS.
    [Graphical view ]
    PANTHERi PTHR11802. PTHR11802. 1 hit.
    Pfami PF00450. Peptidase_S10. 1 hit.
    [Graphical view ]
    PRINTSi PR00724. CRBOXYPTASEC.
    SUPFAMi SSF53474. SSF53474. 2 hits.
    PROSITEi PS00131. CARBOXYPEPT_SER_SER. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC MYA-4605 / CBS 113480.

    Entry informationi

    Entry nameiSPCA_ARTOC
    AccessioniPrimary (citable) accession number: C5FW30
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: September 22, 2009
    Last sequence update: July 28, 2009
    Last modified: October 1, 2014
    This is version 30 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Peptidase families
      Classification of peptidase families and list of entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3