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C5FSW4

- XKS1_ARTOC

UniProt

C5FSW4 - XKS1_ARTOC

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Protein

Probable D-xylulose kinase A

Gene
xkiA, MCYG_05786
Organism
Arthroderma otae (strain ATCC MYA-4605 / CBS 113480) (Microsporum canis)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at transcript leveli

Functioni

Highly specific D-xylulose kinase which participates in the catabolism of xylose. Xylose is a major component of hemicelluloses such as xylan. Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway By similarity.

Catalytic activityi

ATP + D-xylulose = ADP + D-xylulose 5-phosphate.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei98 – 981Substrate By similarity
Binding sitei279 – 2791Substrate By similarity
Binding sitei280 – 2801Substrate By similarity
Binding sitei363 – 3631ATP By similarity
Binding sitei474 – 4741ATP By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi470 – 4712ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. xylulokinase activity Source: UniProtKB-EC

GO - Biological processi

  1. D-xylose metabolic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Carbohydrate metabolism, Xylose metabolism

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable D-xylulose kinase A (EC:2.7.1.17)
Short name:
Xylulokinase A
Gene namesi
Name:xkiA
ORF Names:MCYG_05786
OrganismiArthroderma otae (strain ATCC MYA-4605 / CBS 113480) (Microsporum canis)
Taxonomic identifieri554155 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeOnygenalesArthrodermataceaeArthroderma
ProteomesiUP000002035: Unassembled WGS sequence

Subcellular locationi

Cytoplasm By similarity

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 570570Probable D-xylulose kinase APRO_0000393525Add
BLAST

Expressioni

Inductioni

By D-xylose, L-arabinose or L-arabitol.

Structurei

3D structure databases

ProteinModelPortaliC5FSW4.

Family & Domainsi

Sequence similaritiesi

Belongs to the FGGY kinase family.

Phylogenomic databases

OrthoDBiEOG7CRTZN.

Family and domain databases

InterProiIPR018485. Carb_kinase_FGGY_C.
IPR018484. Carb_kinase_FGGY_N.
[Graphical view]
PfamiPF02782. FGGY_C. 1 hit.
PF00370. FGGY_N. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C5FSW4-1 [UniParc]FASTAAdd to Basket

« Hide

MGSSGGPLYI GFDLSTQQLK GLVVSSDLKV VHIAKFDFDS DSKGFNISKG    50
VLTNEDEGEV FAPVAMWLQA LDAVLQDLKH QGLDFSLVRG ISGAGQQHGS 100
VYWNESAEEI LGGLDGGKTL EDQLQQALSY PYSPNWQDSS TQRECDEFDA 150
FLGSEEELAR VTGSKAHHIL RFQRKHPDAY RKTSRISLVS SFLASIFLGS 200
VAPFDISDVC GMNLWDMPMN RWNERLLKLC AGEAGPEELK KKLGDVPHDG 250
GQELGKISSY FAKRYSFHPD CAITPSTGDN PATILALPLR PLDAMVSLGT 300
STTFLMSTPQ YKPDPSTHFF NHPTTPGLYM FMLCYKNGGL AREQVRDAIN 350
ATSGEKTDPS NPWSNFDRVL LETPPGGQKA GSGPMKMGLF FPRPEIVPNL 400
GEGEWHFNYT PGQANEELKE TDEGWTHPRD DARAIVESQF LSLRLRSKEL 450
VHSPSGGVPP QPRRIYLVGG GSRNAAIAKV AGEVLGGIEG VYKLDVGENA 500
CALGAAYKAV WALERAPDQT FEDLIGRRWR EDEFVEKIAD GFQPDIFEKY 550
RQAVQGFEKM EKQVLMEAKQ 570
Length:570
Mass (Da):62,891
Last modified:July 28, 2009 - v1
Checksum:i30B542C940D3778D
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DS995705 Genomic DNA. Translation: EEQ32967.1.
RefSeqiXP_002845917.1. XM_002845871.1.

Genome annotation databases

GeneIDi9224217.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DS995705 Genomic DNA. Translation: EEQ32967.1 .
RefSeqi XP_002845917.1. XM_002845871.1.

3D structure databases

ProteinModelPortali C5FSW4.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 9224217.

Phylogenomic databases

OrthoDBi EOG7CRTZN.

Family and domain databases

InterProi IPR018485. Carb_kinase_FGGY_C.
IPR018484. Carb_kinase_FGGY_N.
[Graphical view ]
Pfami PF02782. FGGY_C. 1 hit.
PF00370. FGGY_N. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC MYA-4605 / CBS 113480.

Entry informationi

Entry nameiXKS1_ARTOC
AccessioniPrimary (citable) accession number: C5FSW4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 20, 2010
Last sequence update: July 28, 2009
Last modified: April 16, 2014
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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