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C5FSW4

- XKS1_ARTOC

UniProt

C5FSW4 - XKS1_ARTOC

Protein

Probable D-xylulose kinase A

Gene

xkiA

Organism
Arthroderma otae (strain ATCC MYA-4605 / CBS 113480) (Microsporum canis)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 27 (01 Oct 2014)
      Sequence version 1 (28 Jul 2009)
      Previous versions | rss
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    Functioni

    Highly specific D-xylulose kinase which participates in the catabolism of xylose. Xylose is a major component of hemicelluloses such as xylan. Most fungi utilize D-xylose via three enzymatic reactions, xylose reductase (XR), xylitol dehydrogenase (XDH), and xylulokinase, to form xylulose 5-phosphate, which enters pentose phosphate pathway By similarity.By similarity

    Catalytic activityi

    ATP + D-xylulose = ADP + D-xylulose 5-phosphate.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei98 – 981SubstrateBy similarity
    Binding sitei279 – 2791SubstrateBy similarity
    Binding sitei280 – 2801SubstrateBy similarity
    Binding sitei363 – 3631ATPBy similarity
    Binding sitei474 – 4741ATPBy similarity

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi470 – 4712ATPBy similarity

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. xylulokinase activity Source: UniProtKB-EC

    GO - Biological processi

    1. D-xylose metabolic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    Kinase, Transferase

    Keywords - Biological processi

    Carbohydrate metabolism, Xylose metabolism

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable D-xylulose kinase A (EC:2.7.1.17)
    Short name:
    Xylulokinase A
    Gene namesi
    Name:xkiA
    ORF Names:MCYG_05786
    OrganismiArthroderma otae (strain ATCC MYA-4605 / CBS 113480) (Microsporum canis)
    Taxonomic identifieri554155 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeOnygenalesArthrodermataceaeArthroderma
    ProteomesiUP000002035: Unassembled WGS sequence

    Subcellular locationi

    Cytoplasm By similarity

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 570570Probable D-xylulose kinase APRO_0000393525Add
    BLAST

    Expressioni

    Inductioni

    By D-xylose, L-arabinose or L-arabitol.

    Structurei

    3D structure databases

    ProteinModelPortaliC5FSW4.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the FGGY kinase family.Curated

    Phylogenomic databases

    OrthoDBiEOG7CRTZN.

    Family and domain databases

    InterProiIPR018485. Carb_kinase_FGGY_C.
    IPR018484. Carb_kinase_FGGY_N.
    [Graphical view]
    PfamiPF02782. FGGY_C. 1 hit.
    PF00370. FGGY_N. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    C5FSW4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGSSGGPLYI GFDLSTQQLK GLVVSSDLKV VHIAKFDFDS DSKGFNISKG    50
    VLTNEDEGEV FAPVAMWLQA LDAVLQDLKH QGLDFSLVRG ISGAGQQHGS 100
    VYWNESAEEI LGGLDGGKTL EDQLQQALSY PYSPNWQDSS TQRECDEFDA 150
    FLGSEEELAR VTGSKAHHIL RFQRKHPDAY RKTSRISLVS SFLASIFLGS 200
    VAPFDISDVC GMNLWDMPMN RWNERLLKLC AGEAGPEELK KKLGDVPHDG 250
    GQELGKISSY FAKRYSFHPD CAITPSTGDN PATILALPLR PLDAMVSLGT 300
    STTFLMSTPQ YKPDPSTHFF NHPTTPGLYM FMLCYKNGGL AREQVRDAIN 350
    ATSGEKTDPS NPWSNFDRVL LETPPGGQKA GSGPMKMGLF FPRPEIVPNL 400
    GEGEWHFNYT PGQANEELKE TDEGWTHPRD DARAIVESQF LSLRLRSKEL 450
    VHSPSGGVPP QPRRIYLVGG GSRNAAIAKV AGEVLGGIEG VYKLDVGENA 500
    CALGAAYKAV WALERAPDQT FEDLIGRRWR EDEFVEKIAD GFQPDIFEKY 550
    RQAVQGFEKM EKQVLMEAKQ 570
    Length:570
    Mass (Da):62,891
    Last modified:July 28, 2009 - v1
    Checksum:i30B542C940D3778D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DS995705 Genomic DNA. Translation: EEQ32967.1.
    RefSeqiXP_002845917.1. XM_002845871.1.

    Genome annotation databases

    GeneIDi9224217.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    DS995705 Genomic DNA. Translation: EEQ32967.1 .
    RefSeqi XP_002845917.1. XM_002845871.1.

    3D structure databases

    ProteinModelPortali C5FSW4.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 9224217.

    Phylogenomic databases

    OrthoDBi EOG7CRTZN.

    Family and domain databases

    InterProi IPR018485. Carb_kinase_FGGY_C.
    IPR018484. Carb_kinase_FGGY_N.
    [Graphical view ]
    Pfami PF02782. FGGY_C. 1 hit.
    PF00370. FGGY_N. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC MYA-4605 / CBS 113480.

    Entry informationi

    Entry nameiXKS1_ARTOC
    AccessioniPrimary (citable) accession number: C5FSW4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 20, 2010
    Last sequence update: July 28, 2009
    Last modified: October 1, 2014
    This is version 27 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3