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Protein

Putative dipeptidase MCYG_02918

Gene

MCYG_02918

Organism
Arthroderma otae (strain ATCC MYA-4605 / CBS 113480) (Microsporum canis)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Hydrolyzes a wide range of dipeptides.By similarity

Catalytic activityi

Hydrolysis of dipeptides.PROSITE-ProRule annotation

Cofactori

Zn2+PROSITE-ProRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi55 – 551Zinc 1; catalyticPROSITE-ProRule annotation
Metal bindingi57 – 571Zinc 1; catalyticPROSITE-ProRule annotation
Metal bindingi167 – 1671Zinc 1; catalyticPROSITE-ProRule annotation
Metal bindingi167 – 1671Zinc 2; catalyticPROSITE-ProRule annotation
Binding sitei194 – 1941SubstratePROSITE-ProRule annotation
Metal bindingi238 – 2381Zinc 2; catalyticPROSITE-ProRule annotation
Metal bindingi259 – 2591Zinc 2; catalyticPROSITE-ProRule annotation
Binding sitei270 – 2701SubstratePROSITE-ProRule annotation
Binding sitei330 – 3301SubstratePROSITE-ProRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Dipeptidase, Hydrolase, Metalloprotease, Protease

Keywords - Ligandi

Metal-binding, Zinc

Protein family/group databases

MEROPSiM19.A01.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative dipeptidase MCYG_02918 (EC:3.4.13.19)
Gene namesi
ORF Names:MCYG_02918
OrganismiArthroderma otae (strain ATCC MYA-4605 / CBS 113480) (Microsporum canis)
Taxonomic identifieri554155 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeOnygenalesArthrodermataceaeArthroderma
ProteomesiUP000002035 Componenti: Unassembled WGS sequence

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2929Sequence AnalysisAdd
BLAST
Chaini30 – 427398Putative dipeptidase MCYG_02918PRO_0000411212Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi106 ↔ 196PROSITE-ProRule annotation
Glycosylationi402 – 4021N-linked (GlcNAc...)Sequence Analysis

Keywords - PTMi

Disulfide bond, Glycoprotein

Interactioni

Protein-protein interaction databases

STRINGi554155.XP_002847412.1.

Structurei

3D structure databases

ProteinModelPortaliC5FK77.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase M19 family.PROSITE-ProRule annotation

Keywords - Domaini

Signal

Phylogenomic databases

OrthoDBiEOG7XM371.

Family and domain databases

InterProiIPR008257. Renal_dipep_fam.
[Graphical view]
PANTHERiPTHR10443. PTHR10443. 1 hit.
PfamiPF01244. Peptidase_M19. 1 hit.
[Graphical view]
PROSITEiPS51365. RENAL_DIPEPTIDASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

C5FK77-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAPERRSRLS DAGILVSLLA LTSLVPVQAA VTTSKPDYAK RAERVLRSTP
60 70 80 90 100
LIDGHNDLPF AIRRSTHDQI YDGKVPFETA LKGQTDLPRM RKGRMGGQFW
110 120 130 140 150
SVYVGCPSDP NTPIDFPTFA TRDTLEQIDV ARRLVDKYSK DLMYCDNPAC
160 170 180 190 200
AKKAFREGKI GSFIGIEGGH QVGSSIAALR QAFYAGARYM TLTHNCDNAW
210 220 230 240 250
ATAASTVRAG KPDLGMTEFG PALIKEMNRL GMLVDLSHVS HQTMRDVLKV
260 270 280 290 300
TKAPVIFSHS SAYAVSKHLR NVPDDVLKTV AKNNGVVMVT FVRSFVNIDN
310 320 330 340 350
PDSVTVDDIV KHIFHIAEVA GWDHVGLGGD YDGTTELPKG LEDVSKYPYL
360 370 380 390 400
IEKVLEHGAT EEQARKLIGE NILRVWTEVE KIGKRIQNSG ALPVEEVWQG
410 420
RNWTQSLTKR STFIPTESPT QLEFGCD
Length:427
Mass (Da):47,242
Last modified:July 28, 2009 - v1
Checksum:i319F365AADE47FED
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS995703 Genomic DNA. Translation: EEQ30099.1.
RefSeqiXP_002847412.1. XM_002847366.1.

Genome annotation databases

GeneIDi9224858.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS995703 Genomic DNA. Translation: EEQ30099.1.
RefSeqiXP_002847412.1. XM_002847366.1.

3D structure databases

ProteinModelPortaliC5FK77.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi554155.XP_002847412.1.

Protein family/group databases

MEROPSiM19.A01.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi9224858.

Phylogenomic databases

OrthoDBiEOG7XM371.

Family and domain databases

InterProiIPR008257. Renal_dipep_fam.
[Graphical view]
PANTHERiPTHR10443. PTHR10443. 1 hit.
PfamiPF01244. Peptidase_M19. 1 hit.
[Graphical view]
PROSITEiPS51365. RENAL_DIPEPTIDASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC MYA-4605 / CBS 113480.

Entry informationi

Entry nameiDPEP1_ARTOC
AccessioniPrimary (citable) accession number: C5FK77
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 27, 2011
Last sequence update: July 28, 2009
Last modified: June 24, 2015
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Peptidase families
    Classification of peptidase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.