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C5FGX1

- SCPB_ARTOC

UniProt

C5FGX1 - SCPB_ARTOC

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Protein
Carboxypeptidase S1 homolog B
Gene
SCPB, MCYG_02825
Organism
Arthroderma otae (strain ATCC MYA-4605 / CBS 113480) (Microsporum canis)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Extracellular serine carboxypeptidase that contributes to pathogenicity By similarity.

Catalytic activityi

Preferential release of a C-terminal arginine or lysine residue.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei240 – 2401 By similarity
Active sitei459 – 4591 By similarity
Binding sitei462 – 4621Substrate By similarity
Active sitei517 – 5171 By similarity
Binding sitei518 – 5181Substrate By similarity

GO - Molecular functioni

  1. serine-type carboxypeptidase activity Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. pathogenesis Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Carboxypeptidase, Hydrolase, Protease

Keywords - Biological processi

Virulence

Protein family/group databases

MEROPSiS10.016.

Names & Taxonomyi

Protein namesi
Recommended name:
Carboxypeptidase S1 homolog B (EC:3.4.16.6)
Alternative name(s):
Serine carboxypeptidase B
Short name:
SPCB
Gene namesi
Name:SCPB
ORF Names:MCYG_02825
OrganismiArthroderma otae (strain ATCC MYA-4605 / CBS 113480) (Microsporum canis)
Taxonomic identifieri554155 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeOnygenalesArthrodermataceaeArthroderma
ProteomesiUP000002035: Unassembled WGS sequence

Subcellular locationi

Cell membrane; Lipid-anchorGPI-anchor Reviewed prediction

GO - Cellular componenti

  1. anchored component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2121 Reviewed prediction
Add
BLAST
Chaini22 – 631610Carboxypeptidase S1 homolog B
PRO_0000384121Add
BLAST
Propeptidei632 – 65524Removed in mature form Reviewed prediction
PRO_0000384122Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi51 ↔ 123 By similarity
Glycosylationi130 – 1301N-linked (GlcNAc...) Reviewed prediction
Glycosylationi163 – 1631N-linked (GlcNAc...) Reviewed prediction
Glycosylationi186 – 1861N-linked (GlcNAc...) Reviewed prediction
Glycosylationi266 – 2661N-linked (GlcNAc...) Reviewed prediction
Glycosylationi302 – 3021N-linked (GlcNAc...) Reviewed prediction
Glycosylationi311 – 3111N-linked (GlcNAc...) Reviewed prediction
Disulfide bondi328 ↔ 364 By similarity
Disulfide bondi335 ↔ 357 By similarity
Glycosylationi414 – 4141N-linked (GlcNAc...) Reviewed prediction
Glycosylationi475 – 4751N-linked (GlcNAc...) Reviewed prediction
Glycosylationi493 – 4931N-linked (GlcNAc...) Reviewed prediction
Glycosylationi506 – 5061N-linked (GlcNAc...) Reviewed prediction
Glycosylationi598 – 5981N-linked (GlcNAc...) Reviewed prediction
Glycosylationi612 – 6121N-linked (GlcNAc...) Reviewed prediction
Lipidationi631 – 6311GPI-anchor amidated glycine Reviewed prediction

Keywords - PTMi

Disulfide bond, Glycoprotein, GPI-anchor, Lipoprotein

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase S10 family.

Keywords - Domaini

Signal

Phylogenomic databases

OrthoDBiEOG7FV40C.

Family and domain databases

Gene3Di3.40.50.1820. 2 hits.
InterProiIPR029058. AB_hydrolase.
IPR001563. Peptidase_S10.
IPR018202. Peptidase_S10_AS.
[Graphical view]
PANTHERiPTHR11802. PTHR11802. 1 hit.
PfamiPF00450. Peptidase_S10. 1 hit.
[Graphical view]
PRINTSiPR00724. CRBOXYPTASEC.
SUPFAMiSSF53474. SSF53474. 2 hits.
PROSITEiPS00131. CARBOXYPEPT_SER_SER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

C5FGX1-1 [UniParc]FASTAAdd to Basket

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MRPFARAALC LLAAAGHLAQ AQFPPRPEGV TVLESKFGGG ARISYKEPGL    50
CETTEGVKSY AGYVHLPPGT LKDLGVEQDY PINTFFWFFE ARKDPENAPL 100
SIWMNGGPGS SSMFGMMTEN GPCFVNPDSN STRLNPHSWN NEVNMLYLDQ 150
PVQVGLSYDT LANFTRNLVT DEITKLEPGD PIPEQNATFL VGTYASRNMD 200
TTAKGTRNAA IALWHFAQVW FQEFPGYHPR DSRISIATES YGGRYGPAFT 250
AFFEEQNQKI KDGTWNGSEG NRHVLHLDTL MIVNGCIDRL VQWPAYPQMA 300
YNNTYSIEAV NASIHEGMLD ALYREGGCRD KINHCRSISA VSDPENIGIN 350
AMVNDVCKDA ETFCSTEVRD PYQEFSGRNY YDIGQLDPSP FPAPFYMAWL 400
NQPHVQAALG VPLNWTQSND VVTTAFRAIG DYPRPGWLED LAYLLENGIK 450
VSLVYGDRDY ACNWFGGELS SLAINYTDTQ NFHNAGYAGI QVNSSYIGGQ 500
VRQYGNLSFS RVYEAGHEVP SYQPETALQI FHRALFNKDI ATGTIDTSSR 550
REDGKFYGSS GPSDSFVFKN EPPPQHVHFC HILDTSTCTK EQIESVENGT 600
AVVRSWIVVD SNSTSLFPEV VGSAEPTPMP GAALVSGRIK FHVHVIKSFD 650
YYIFI 655
Length:655
Mass (Da):72,791
Last modified:July 28, 2009 - v1
Checksum:i4E95D4568D454EB5
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DS995702 Genomic DNA. Translation: EEQ30006.1.
RefSeqiXP_002849891.1. XM_002849845.1.

Genome annotation databases

GeneIDi9223265.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DS995702 Genomic DNA. Translation: EEQ30006.1 .
RefSeqi XP_002849891.1. XM_002849845.1.

3D structure databases

ModBasei Search...

Protein family/group databases

MEROPSi S10.016.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 9223265.

Phylogenomic databases

OrthoDBi EOG7FV40C.

Family and domain databases

Gene3Di 3.40.50.1820. 2 hits.
InterProi IPR029058. AB_hydrolase.
IPR001563. Peptidase_S10.
IPR018202. Peptidase_S10_AS.
[Graphical view ]
PANTHERi PTHR11802. PTHR11802. 1 hit.
Pfami PF00450. Peptidase_S10. 1 hit.
[Graphical view ]
PRINTSi PR00724. CRBOXYPTASEC.
SUPFAMi SSF53474. SSF53474. 2 hits.
PROSITEi PS00131. CARBOXYPEPT_SER_SER. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC MYA-4605 / CBS 113480.

Entry informationi

Entry nameiSCPB_ARTOC
AccessioniPrimary (citable) accession number: C5FGX1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: July 28, 2009
Last modified: June 11, 2014
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Peptidase families
    Classification of peptidase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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