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C5FGX1

- SCPB_ARTOC

UniProt

C5FGX1 - SCPB_ARTOC

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Protein

Carboxypeptidase S1 homolog B

Gene

SCPB

Organism
Arthroderma otae (strain ATCC MYA-4605 / CBS 113480) (Microsporum canis)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Extracellular serine carboxypeptidase that contributes to pathogenicity.By similarity

Catalytic activityi

Preferential release of a C-terminal arginine or lysine residue.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei240 – 2401PROSITE-ProRule annotation
Active sitei459 – 4591PROSITE-ProRule annotation
Binding sitei462 – 4621SubstrateBy similarity
Active sitei517 – 5171PROSITE-ProRule annotation
Binding sitei518 – 5181SubstrateBy similarity

GO - Molecular functioni

  1. serine-type carboxypeptidase activity Source: InterPro

GO - Biological processi

  1. pathogenesis Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Carboxypeptidase, Hydrolase, Protease

Keywords - Biological processi

Virulence

Protein family/group databases

MEROPSiS10.016.

Names & Taxonomyi

Protein namesi
Recommended name:
Carboxypeptidase S1 homolog B (EC:3.4.16.6)
Alternative name(s):
Serine carboxypeptidase B
Short name:
SPCB
Gene namesi
Name:SCPB
ORF Names:MCYG_02825
OrganismiArthroderma otae (strain ATCC MYA-4605 / CBS 113480) (Microsporum canis)
Taxonomic identifieri554155 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeOnygenalesArthrodermataceaeArthroderma
ProteomesiUP000002035: Unassembled WGS sequence

Subcellular locationi

GO - Cellular componenti

  1. anchored component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2121Sequence AnalysisAdd
BLAST
Chaini22 – 631610Carboxypeptidase S1 homolog BPRO_0000384121Add
BLAST
Propeptidei632 – 65524Removed in mature formSequence AnalysisPRO_0000384122Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi51 ↔ 123By similarity
Glycosylationi130 – 1301N-linked (GlcNAc...)Sequence Analysis
Glycosylationi163 – 1631N-linked (GlcNAc...)Sequence Analysis
Glycosylationi186 – 1861N-linked (GlcNAc...)Sequence Analysis
Glycosylationi266 – 2661N-linked (GlcNAc...)Sequence Analysis
Glycosylationi302 – 3021N-linked (GlcNAc...)Sequence Analysis
Glycosylationi311 – 3111N-linked (GlcNAc...)Sequence Analysis
Disulfide bondi328 ↔ 364By similarity
Disulfide bondi335 ↔ 357By similarity
Glycosylationi414 – 4141N-linked (GlcNAc...)Sequence Analysis
Glycosylationi475 – 4751N-linked (GlcNAc...)Sequence Analysis
Glycosylationi493 – 4931N-linked (GlcNAc...)Sequence Analysis
Glycosylationi506 – 5061N-linked (GlcNAc...)Sequence Analysis
Glycosylationi598 – 5981N-linked (GlcNAc...)Sequence Analysis
Glycosylationi612 – 6121N-linked (GlcNAc...)Sequence Analysis
Lipidationi631 – 6311GPI-anchor amidated glycineSequence Analysis

Keywords - PTMi

Disulfide bond, Glycoprotein, GPI-anchor, Lipoprotein

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase S10 family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

OrthoDBiEOG7FV40C.

Family and domain databases

Gene3Di3.40.50.1820. 2 hits.
InterProiIPR029058. AB_hydrolase.
IPR001563. Peptidase_S10.
IPR018202. Peptidase_S10_AS.
[Graphical view]
PANTHERiPTHR11802. PTHR11802. 1 hit.
PfamiPF00450. Peptidase_S10. 1 hit.
[Graphical view]
PRINTSiPR00724. CRBOXYPTASEC.
SUPFAMiSSF53474. SSF53474. 2 hits.
PROSITEiPS00131. CARBOXYPEPT_SER_SER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

C5FGX1-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MRPFARAALC LLAAAGHLAQ AQFPPRPEGV TVLESKFGGG ARISYKEPGL
60 70 80 90 100
CETTEGVKSY AGYVHLPPGT LKDLGVEQDY PINTFFWFFE ARKDPENAPL
110 120 130 140 150
SIWMNGGPGS SSMFGMMTEN GPCFVNPDSN STRLNPHSWN NEVNMLYLDQ
160 170 180 190 200
PVQVGLSYDT LANFTRNLVT DEITKLEPGD PIPEQNATFL VGTYASRNMD
210 220 230 240 250
TTAKGTRNAA IALWHFAQVW FQEFPGYHPR DSRISIATES YGGRYGPAFT
260 270 280 290 300
AFFEEQNQKI KDGTWNGSEG NRHVLHLDTL MIVNGCIDRL VQWPAYPQMA
310 320 330 340 350
YNNTYSIEAV NASIHEGMLD ALYREGGCRD KINHCRSISA VSDPENIGIN
360 370 380 390 400
AMVNDVCKDA ETFCSTEVRD PYQEFSGRNY YDIGQLDPSP FPAPFYMAWL
410 420 430 440 450
NQPHVQAALG VPLNWTQSND VVTTAFRAIG DYPRPGWLED LAYLLENGIK
460 470 480 490 500
VSLVYGDRDY ACNWFGGELS SLAINYTDTQ NFHNAGYAGI QVNSSYIGGQ
510 520 530 540 550
VRQYGNLSFS RVYEAGHEVP SYQPETALQI FHRALFNKDI ATGTIDTSSR
560 570 580 590 600
REDGKFYGSS GPSDSFVFKN EPPPQHVHFC HILDTSTCTK EQIESVENGT
610 620 630 640 650
AVVRSWIVVD SNSTSLFPEV VGSAEPTPMP GAALVSGRIK FHVHVIKSFD

YYIFI
Length:655
Mass (Da):72,791
Last modified:July 28, 2009 - v1
Checksum:i4E95D4568D454EB5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS995702 Genomic DNA. Translation: EEQ30006.1.
RefSeqiXP_002849891.1. XM_002849845.1.

Genome annotation databases

GeneIDi9223265.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DS995702 Genomic DNA. Translation: EEQ30006.1 .
RefSeqi XP_002849891.1. XM_002849845.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein family/group databases

MEROPSi S10.016.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 9223265.

Phylogenomic databases

OrthoDBi EOG7FV40C.

Family and domain databases

Gene3Di 3.40.50.1820. 2 hits.
InterProi IPR029058. AB_hydrolase.
IPR001563. Peptidase_S10.
IPR018202. Peptidase_S10_AS.
[Graphical view ]
PANTHERi PTHR11802. PTHR11802. 1 hit.
Pfami PF00450. Peptidase_S10. 1 hit.
[Graphical view ]
PRINTSi PR00724. CRBOXYPTASEC.
SUPFAMi SSF53474. SSF53474. 2 hits.
PROSITEi PS00131. CARBOXYPEPT_SER_SER. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC MYA-4605 / CBS 113480.

Entry informationi

Entry nameiSCPB_ARTOC
AccessioniPrimary (citable) accession number: C5FGX1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: July 28, 2009
Last modified: October 29, 2014
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Peptidase families
    Classification of peptidase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3