Skip Header

Contribute Send feedback
Read comments (?) or add your own

C5E8M2 (C5E8M2_BIFLI) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 16. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Phosphopantetheine adenylyltransferase HAMAP MF_00151
EC=2.7.7.3 HAMAP MF_00151
Alternative name(s):
Dephospho-CoA pyrophosphorylase HAMAP MF_00151
Pantetheine-phosphate adenylyltransferase HAMAP MF_00151
Gene names
Name:coaD HAMAP MF_00151
ORF Names:BLIG_00293 EMBL EEQ54344.1
OrganismBifidobacterium longum subsp. infantis CCUG 52486 EMBL EEQ54344.1
Taxonomic identifier537937 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Bifidobacteriales › Bifidobacteriaceae › Bifidobacterium

Protein attributes

Sequence length166 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate By similarity. HAMAP MF_00151

Catalytic activity

ATP + pantetheine 4'-phosphate = diphosphate + 3'-dephospho-CoA. HAMAP MF_00151

Pathway

Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 4/5. HAMAP MF_00151

Subunit structure

Homohexamer By similarity. HAMAP MF_00151

Subcellular location

Cytoplasm By similarity HAMAP MF_00151.

Sequence similarities

Belongs to the bacterial CoaD family. HAMAP MF_00151

Sequences

Sequence LengthMass (Da)Tools
C5E8M2 [UniParc].

Last modified July 28, 2009. Version 1.
Checksum: 4622E8EDCBF407BD

FASTA16617,838
        10         20         30         40         50         60 
MTIAVCPGSY DPVTAGHLDV IERSARFFDE VHVVVAVNAA KTPMFSEATR VDVIRRALDK 

        70         80         90        100        110        120 
AGCKNVTVSS TDGLITDYCK KVGATVIIKG LRQNGDYEAE LGMALVNRKL AGIETLFLPA 

       130        140        150        160 
DPILEHISSS IVKDVARHGG DVTGMVPDCV VPMLADALAE ERQRKD

« Hide

References

[1]"Annotation of Bifidobacterium longum subsp. infantis CCUG 52486."
The Broad Institute Genome Sequencing Platform
Gougoulias C., Tuohy K.M., Gibson G.R., Ward D., Mehta T., Young S., Jaffe D., Gnerre S., Berlin A., Heiman D., Hepburn T., Shea T., Sykes S., Alvarado L., Kodira C., Borodovsky M., Lander E., Galagan J., Nusbaum C., Birren B.
Submitted (AUG-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: CCUG 52486 EMBL EEQ54344.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		DS990238 Genomic DNA. Translation: EEQ54344.1.

3D structure databases

ProteinModelPortalC5E8M2.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

PATRIC26495172. VBIBifLon94805_0285.

Family and domain databases

HAMAPMF_00151. PPAT_bact.
[Tree]
InterProIPR004821. Cyt_trans-rel.
IPR004820. Cytidylyltransf.
IPR001980. LPS_biosynth.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
Gene3DG3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 1 hit.
PfamPF01467. CTP_transf_2. 1 hit.
[Graphical view]
PRINTSPR01020. LPSBIOSNTHSS.
TIGRFAMsTIGR01510. CoaD_prev_kdtB. 1 hit.
TIGR00125. Cyt_tran_rel. 1 hit.
ProtoNetSearch...

Entry information

Entry nameC5E8M2_BIFLI
AccessionPrimary (citable) accession number: C5E8M2
Entry history
Integrated into UniProtKB/TrEMBL: July 28, 2009
Last sequence update: July 28, 2009
Last modified: December 14, 2011
This is version 16 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info