Skip Header

Contribute Send feedback
Read comments (?) or add your own

C5E304 (C5E304_LACTC) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 31. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Protein attributes

Sequence length307 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin By similarity. PIRNR PIRNR000241 RuleBase RU004455

Catalytic activity

Urate + O2 + H2O = 5-hydroxyisourate + H2O2. PIRNR PIRNR000241 RuleBase RU004455

Pathway

Purine metabolism; urate degradation; (S)-allantoin from urate: step 1/3. PIRNR PIRNR000241

Subcellular location

Peroxisome By similarity PIRNR PIRNR000241.

Sequence similarities

Belongs to the uricase family. PIRNR PIRNR000241 RuleBase RU004455

Ontologies

Keywords
   Biological processPurine metabolism PIRNR PIRNR000241 RuleBase RU004455
   Cellular componentPeroxisome PIRNR PIRNR000241
   Molecular functionOxidoreductase PIRNR PIRNR000241 RuleBase RU004455
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processpurine nucleobase metabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

urate catabolic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentperoxisome

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionurate oxidase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region238 – 2392Substrate binding By similarity PIRSR PIRSR000241-2
Motif305 – 3073Microbody targeting signal (Potential) By similarity PIRSR PIRSR000241-3

Sites

Active site1831Charge relay system By similarity PIRSR PIRSR000241-1
Active site2391Charge relay system By similarity PIRSR PIRSR000241-1
Binding site1831Substrate By similarity PIRSR PIRSR000241-2

Sequences

Sequence LengthMass (Da)Tools
C5E304 [UniParc].

Last modified July 28, 2009. Version 1.
Checksum: A002CAF3A61A0A1E

FASTA30734,745
        10         20         30         40         50         60 
MPYSYLESST YGKDNVKFLK VKKDKTNPKV HEIMEATVCV LLKGDFEISY TEADNAPIVP 

        70         80         90        100        110        120 
TDTVKNTILI LAKKYDTFPI EKFAAKLALH FTSKYSHVSG LTVKITQDRW VKFDVDGKES 

       130        140        150        160        170        180 
QHSFVHQGPE KKITFLDYDK KNGPSNYSLS SSIKDLTVLK STNSMFYGYN VCDYTTLKPT 

       190        200        210        220        230        240 
TDRILSTDIF ATMDWCPKKL GCLESIASGS KDEIFTNAYN SARDITLDIF AKENSPSVQA 

       250        260        270        280        290        300 
TMYNMATAIL KIAPQVAYVS YELPNKHYFL FDLKWFQGLE NDNELFYPSP HPNGLIKCKV 


GRNGSKL

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CU928180 Genomic DNA. Translation: CAR30415.1.
RefSeqXP_002556277.1. XM_002556231.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRING559295.KLTH0H09262g.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID8294602.
KEGGlth:KLTH0H09262g.

Phylogenomic databases

eggNOGCOG3648.
HOGENOMHOG000250659.
KOK00365.
OrthoDBEOG4H1F58.

Enzyme and pathway databases

UniPathwayUPA00394; UER00650.

Family and domain databases

Gene3D3.10.270.10. 1 hit.
InterProIPR002042. Uricase.
IPR019842. Uricase_CS.
[Graphical view]
PANTHERPTHR10395:SF1. PTHR10395:SF1. 1 hit.
PfamPF01014. Uricase. 2 hits.
[Graphical view]
PIRSFPIRSF000241. Urate_oxidase. 1 hit.
PRINTSPR00093. URICASE.
TIGRFAMsTIGR03383. urate_oxi. 1 hit.
PROSITEPS00366. URICASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC5E304_LACTC
AccessionPrimary (citable) accession number: C5E304
Entry history
Integrated into UniProtKB/TrEMBL: July 28, 2009
Last sequence update: July 28, 2009
Last modified: May 1, 2013
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info