Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

C5E2W8

- C5E2W8_LACTC

UniProt

C5E2W8 - C5E2W8_LACTC

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Mitogen-activated protein kinase

Gene

KLTH0H08316g

Organism
Lachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284) (Yeast) (Kluyveromyces thermotolerans)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.UniRule annotationSAAS annotation

Cofactori

Magnesium.UniRule annotation

Enzyme regulationi

Activated by threonine and tyrosine phosphorylation.UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. MAP kinase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinaseUniRule annotationSAAS annotation, Transferase

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, MagnesiumUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Mitogen-activated protein kinaseUniRule annotation (EC:2.7.11.24UniRule annotation)
Gene namesi
Ordered Locus Names:KLTH0H08316gImported
OrganismiLachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284) (Yeast) (Kluyveromyces thermotolerans)Imported
Taxonomic identifieri559295 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeLachancea
ProteomesiUP000002036: Chromosome H

Interactioni

Protein-protein interaction databases

STRINGi559295.KLTH0H08316g.

Structurei

3D structure databases

ProteinModelPortaliC5E2W8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.UniRule annotation
Contains 1 protein kinase domain.UniRule annotation
Contains protein kinase domain.SAAS annotation

Phylogenomic databases

eggNOGiCOG0515.
HOGENOMiHOG000233024.
InParanoidiC5E2W8.
KOiK04371.
OrthoDBiEOG7K3TWD.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR003527. MAP_kinase_CS.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR002290. Ser/Thr_dual-sp_kinase.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS01351. MAPK. 1 hit.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C5E2W8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MGKKIVFNIS SEFQLQQMLG EGAYGVVCSA RHLPTGQMVA IKKIEPFDRP
60 70 80 90 100
LFCLRTLREI KLLRCFQHEN IISIFDIQRP ASFETFSEVY IIQELMDTDL
110 120 130 140 150
HRVITTQTLS DDHVQYFVYQ ILRALKCLHG AEVIHRDLKP SNLLVNANCD
160 170 180 190 200
LKLCDFGLAR CAGGGTKPGD AGHMTEYVAT RWYRAPEVML TAAEYTFAMD
210 220 230 240 250
VWSCGCILAE LLMRRPLFPG KDYHHQLLLI FQVIGSPTAG DLGCVRSKRA
260 270 280 290 300
RQYLNTLPRY AGDGNLRSLV PDASAEALDL LEQMLVFDPR RRITASQALK
310 320 330 340 350
HPYLQAYHDP QDEPATAKVD PALFHFDERK DKLGAGDLKR LLWDEIFGKR

ERTDS
Length:355
Mass (Da):40,348
Last modified:July 28, 2009 - v1
Checksum:iEC604FCEE7D68AD3
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CU928180 Genomic DNA. Translation: CAR30379.1.
RefSeqiXP_002556241.1. XM_002556195.1.

Genome annotation databases

GeneIDi8294559.
KEGGilth:KLTH0H08316g.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CU928180 Genomic DNA. Translation: CAR30379.1 .
RefSeqi XP_002556241.1. XM_002556195.1.

3D structure databases

ProteinModelPortali C5E2W8.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 559295.KLTH0H08316g.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 8294559.
KEGGi lth:KLTH0H08316g.

Phylogenomic databases

eggNOGi COG0515.
HOGENOMi HOG000233024.
InParanoidi C5E2W8.
KOi K04371.
OrthoDBi EOG7K3TWD.

Family and domain databases

InterProi IPR011009. Kinase-like_dom.
IPR003527. MAP_kinase_CS.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR002290. Ser/Thr_dual-sp_kinase.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view ]
Pfami PF00069. Pkinase. 1 hit.
[Graphical view ]
SMARTi SM00220. S_TKc. 1 hit.
[Graphical view ]
SUPFAMi SSF56112. SSF56112. 1 hit.
PROSITEi PS01351. MAPK. 1 hit.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Comparative genomics of protoploid Saccharomycetaceae."
    The Genolevures Consortium
    Souciet J.-L., Dujon B., Gaillardin C., Johnston M., Baret P.V., Cliften P., Sherman D.J., Weissenbach J., Westhof E., Wincker P., Jubin C., Poulain J., Barbe V., Segurens B., Artiguenave F., Anthouard V., Vacherie B., Val M.-E.
    , Fulton R.S., Minx P., Wilson R., Durrens P., Jean G., Marck C., Martin T., Nikolski M., Rolland T., Seret M.-L., Casaregola S., Despons L., Fairhead C., Fischer G., Lafontaine I., Leh V., Lemaire M., de Montigny J., Neuveglise C., Thierry A., Blanc-Lenfle I., Bleykasten C., Diffels J., Fritsch E., Frangeul L., Goeffon A., Jauniaux N., Kachouri-Lafond R., Payen C., Potier S., Pribylova L., Ozanne C., Richard G.-F., Sacerdot C., Straub M.-L., Talla E.
    Genome Res. 19:1696-1709(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 56472 / CBS 6340 / NRRL Y-8284Imported.

Entry informationi

Entry nameiC5E2W8_LACTC
AccessioniPrimary (citable) accession number: C5E2W8
Entry historyi
Integrated into UniProtKB/TrEMBL: July 28, 2009
Last sequence update: July 28, 2009
Last modified: October 29, 2014
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3