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Protein

Transcription activator of gluconeogenesis

Gene

ERT1

Organism
Zygosaccharomyces rouxii (strain ATCC 2623 / CBS 732 / NBRC 1130 / NCYC 568 / NRRL Y-229) (Candida mogii)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Transcription factor which regulates nonfermentable carbon utilization. Activator of gluconeogenetic genes (By similarity).By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi41 – 6929Zn(2)-C6 fungal-typeAdd
BLAST

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Activator

Keywords - Biological processi

Gluconeogenesis, Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Transcription activator of gluconeogenesis
Gene namesi
Name:ERT1
Ordered Locus Names:ZYRO0G21582g
OrganismiZygosaccharomyces rouxii (strain ATCC 2623 / CBS 732 / NBRC 1130 / NCYC 568 / NRRL Y-229) (Candida mogii)
Taxonomic identifieri559307 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeZygosaccharomyces
Proteomesi
  • UP000008536 Componenti: Chromosome G

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 512512Transcription activator of gluconeogenesisPRO_0000406477Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliC5E1J9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini391 – 46373PASPROSITE-ProRule annotationAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi171 – 1799Poly-Ala

Sequence similaritiesi

Belongs to the ERT1/acuK family.Curated
Contains 1 PAS (PER-ARNT-SIM) domain.PROSITE-ProRule annotation

Phylogenomic databases

HOGENOMiHOG000247854.
InParanoidiC5E1J9.
OrthoDBiEOG70KGZB.

Family and domain databases

InterProiIPR000014. PAS.
IPR013767. PAS_fold.
IPR001138. Zn2-C6_fun-type_DNA-bd.
[Graphical view]
PfamiPF00989. PAS. 1 hit.
PF00172. Zn_clus. 1 hit.
[Graphical view]
SMARTiSM00066. GAL4. 1 hit.
SM00091. PAS. 1 hit.
[Graphical view]
SUPFAMiSSF55785. SSF55785. 1 hit.
SSF57701. SSF57701. 1 hit.
TIGRFAMsiTIGR00229. sensory_box. 1 hit.
PROSITEiPS50112. PAS. 1 hit.
PS00463. ZN2_CY6_FUNGAL_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C5E1J9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGGGSGPSDE FANILPHFSQ VDSSVPVSSG KKSRRNTHVA CVNCSKWHVS
60 70 80 90 100
CEAKRPCHRC VVKGLGSTCV DAPRKKSKYL AGIPDASLIR SVHRDNGSQA
110 120 130 140 150
NNSSPDNAGV SHHQEQQNFR DPQHIVHKSK FLSNAADSEY SILSHIINQD
160 170 180 190 200
TLVNKIPIDL LYSGKPNDND AEAAAAVAAK EAANVDLSSP KVDVGPSNTA
210 220 230 240 250
MSSTDVYSML LGPNSREIVA SRIDLFQNHF PLTPVESQYH SLSFKRLPTQ
260 270 280 290 300
DRSGSPKFNA SINQYYLNKE ISMLPEVINA AMRQQRSVGD KSVSFALECV
310 320 330 340 350
SPDAYQLSGN SEWRHSLRYS TSMEIYQLIN EPFSHTTGFH HLYTYLRKRF
360 370 380 390 400
NRKDLIEMSG CLAEFRPIFI ACTASLTEQD MIFMEQCYQR TLLEYAKFIA
410 420 430 440 450
QIGTPTCVWR RNGQISYVNE EFEILSGWNK EELLNKMTFI VEIMDDESVR
460 470 480 490 500
DYFKTFAKVA YKDFRGSERM KTCNLLTPTR GQIIPCCCMW TLKRDVSGLP
510
LMILGNFMPI IA
Length:512
Mass (Da):57,475
Last modified:July 28, 2009 - v1
Checksum:i2AF91A1F8D049842
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU928179 Genomic DNA. Translation: CAR29983.1.
RefSeqiXP_002498916.1. XM_002498871.1.

Genome annotation databases

EnsemblFungiiCAR29983; CAR29983; ZYRO0G21582g.
GeneIDi8206752.
KEGGizro:ZYRO0G21582g.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU928179 Genomic DNA. Translation: CAR29983.1.
RefSeqiXP_002498916.1. XM_002498871.1.

3D structure databases

ProteinModelPortaliC5E1J9.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiCAR29983; CAR29983; ZYRO0G21582g.
GeneIDi8206752.
KEGGizro:ZYRO0G21582g.

Phylogenomic databases

HOGENOMiHOG000247854.
InParanoidiC5E1J9.
OrthoDBiEOG70KGZB.

Family and domain databases

InterProiIPR000014. PAS.
IPR013767. PAS_fold.
IPR001138. Zn2-C6_fun-type_DNA-bd.
[Graphical view]
PfamiPF00989. PAS. 1 hit.
PF00172. Zn_clus. 1 hit.
[Graphical view]
SMARTiSM00066. GAL4. 1 hit.
SM00091. PAS. 1 hit.
[Graphical view]
SUPFAMiSSF55785. SSF55785. 1 hit.
SSF57701. SSF57701. 1 hit.
TIGRFAMsiTIGR00229. sensory_box. 1 hit.
PROSITEiPS50112. PAS. 1 hit.
PS00463. ZN2_CY6_FUNGAL_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Comparative genomics of protoploid Saccharomycetaceae."
    The Genolevures Consortium
    Souciet J.-L., Dujon B., Gaillardin C., Johnston M., Baret P.V., Cliften P., Sherman D.J., Weissenbach J., Westhof E., Wincker P., Jubin C., Poulain J., Barbe V., Segurens B., Artiguenave F., Anthouard V., Vacherie B., Val M.-E.
    , Fulton R.S., Minx P., Wilson R., Durrens P., Jean G., Marck C., Martin T., Nikolski M., Rolland T., Seret M.-L., Casaregola S., Despons L., Fairhead C., Fischer G., Lafontaine I., Leh V., Lemaire M., de Montigny J., Neuveglise C., Thierry A., Blanc-Lenfle I., Bleykasten C., Diffels J., Fritsch E., Frangeul L., Goeffon A., Jauniaux N., Kachouri-Lafond R., Payen C., Potier S., Pribylova L., Ozanne C., Richard G.-F., Sacerdot C., Straub M.-L., Talla E.
    Genome Res. 19:1696-1709(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 2623 / CBS 732 / NBRC 1130 / NCYC 568 / NRRL Y-229.

Entry informationi

Entry nameiERT1_ZYGRC
AccessioniPrimary (citable) accession number: C5E1J9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 5, 2011
Last sequence update: July 28, 2009
Last modified: June 8, 2016
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.