ID   C5DUF8_ZYGRC            Unreviewed;       436 AA.
AC   C5DUF8;
DT   28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   28-JUL-2009, sequence version 1.
DT   27-MAR-2024, entry version 75.
DE   RecName: Full=histone deacetylase {ECO:0000256|ARBA:ARBA00012111};
DE            EC=3.5.1.98 {ECO:0000256|ARBA:ARBA00012111};
GN   OrderedLocusNames=ZYRO0C16390g {ECO:0000313|EMBL:CAR27419.1};
OS   Zygosaccharomyces rouxii (strain ATCC 2623 / CBS 732 / NBRC 1130 / NCYC 568
OS   / NRRL Y-229) (Candida mogii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Zygosaccharomyces.
OX   NCBI_TaxID=559307 {ECO:0000313|EMBL:CAR27419.1, ECO:0000313|Proteomes:UP000008536};
RN   [1] {ECO:0000313|Proteomes:UP000008536}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2623 / CBS 732 / BCRC 21506 / NBRC 1130 / NCYC 568 / NRRL
RC   Y-229 {ECO:0000313|Proteomes:UP000008536};
RX   PubMed=19525356; DOI=10.1101/gr.091546.109;
RG   The Genolevures Consortium;
RA   Souciet J.-L., Dujon B., Gaillardin C., Johnston M., Baret P.V.,
RA   Cliften P., Sherman D.J., Weissenbach J., Westhof E., Wincker P., Jubin C.,
RA   Poulain J., Barbe V., Segurens B., Artiguenave F., Anthouard V.,
RA   Vacherie B., Val M.-E., Fulton R.S., Minx P., Wilson R., Durrens P.,
RA   Jean G., Marck C., Martin T., Nikolski M., Rolland T., Seret M.-L.,
RA   Casaregola S., Despons L., Fairhead C., Fischer G., Lafontaine I., Leh V.,
RA   Lemaire M., de Montigny J., Neuveglise C., Thierry A., Blanc-Lenfle I.,
RA   Bleykasten C., Diffels J., Fritsch E., Frangeul L., Goeffon A.,
RA   Jauniaux N., Kachouri-Lafond R., Payen C., Potier S., Pribylova L.,
RA   Ozanne C., Richard G.-F., Sacerdot C., Straub M.-L., Talla E.;
RT   "Comparative genomics of protoploid Saccharomycetaceae.";
RL   Genome Res. 19:1696-1709(2009).
CC   -!- SIMILARITY: Belongs to the histone deacetylase family. HD type 1
CC       subfamily. {ECO:0000256|ARBA:ARBA00006457}.
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DR   EMBL; CU928175; CAR27419.1; -; Genomic_DNA.
DR   RefSeq; XP_002496352.1; XM_002496307.1.
DR   AlphaFoldDB; C5DUF8; -.
DR   STRING; 559307.C5DUF8; -.
DR   GeneID; 8203581; -.
DR   KEGG; zro:ZYRO0C16390g; -.
DR   HOGENOM; CLU_007727_7_8_1; -.
DR   InParanoid; C5DUF8; -.
DR   Proteomes; UP000008536; Chromosome C.
DR   GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:UniProt.
DR   Gene3D; 3.40.800.20; Histone deacetylase domain; 1.
DR   InterPro; IPR000286; His_deacetylse.
DR   InterPro; IPR023801; His_deacetylse_dom.
DR   InterPro; IPR037138; His_deacetylse_dom_sf.
DR   InterPro; IPR023696; Ureohydrolase_dom_sf.
DR   PANTHER; PTHR10625:SF39; HISTONE DEACETYLASE 8; 1.
DR   PANTHER; PTHR10625; HISTONE DEACETYLASE HDAC1-RELATED; 1.
DR   Pfam; PF00850; Hist_deacetyl; 1.
DR   PRINTS; PR01270; HDASUPER.
DR   SUPFAM; SSF52768; Arginase/deacetylase; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000008536}.
FT   DOMAIN          20..373
FT                   /note="Histone deacetylase"
FT                   /evidence="ECO:0000259|Pfam:PF00850"
SQ   SEQUENCE   436 AA;  50334 MW;  6C0B7A7F1B71AF1D CRC64;
     MGKLVIASSQ FQSQVADLLP CNKWRRSQLV HGLIDCYSLL EKFDHVISKP YCDKRELLKF
     HAESYIDTLL NSSYNQLLPY DEAESSWTQL IEMDKDWSHR HDTKVTTHWS TRAQLYEHFQ
     GLRSRKRSAD EVDSNDTPQE IDSKVFNLEG DCPIFSYLPM YCQVVTGATL MLADYIESNT
     QDERTIAINW DGGRHHAMKK RASGFCYVND IVLLIQKLRS KGFQRLSYID FDLHHGDGVE
     RAFQFSSNVQ TISMHLFECG FFPTSGSLED NKKGKNIANI PLAHGLNDEY LNEIVTQVVI
     PLTDRHSPQV IIIQCGGDGL MGDEYNEWQL TIKGLCENIL KIVNRYKNCS IVLLGGGGYN
     PTVMSRFYTY LTGKLIDPNF LQDEDTIIPE HKFIDAYHDE HYKFWAYEME GSLLRKTLKN
     ENEFKFINEI KSHYGI
//