C5DNP3 (C5DNP3_LACTC) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
DNA-directed RNA polymerase RuleBase RU003805
EC=2.7.7.6 RuleBase RU003805

Gene names

Ordered Locus Names:

KLTH0G18744g

Organism

Lachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284) (Yeast) (Kluyveromyces thermotolerans) [Complete proteome] EMBL CAR25404.1

Taxonomic identifier

559295 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Lachancea › Lachancea thermotolerans

Protein attributes

Sequence length	1289 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates By similarity. RuleBase RU003805
Catalytic activity	Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). RuleBase RU003805
Sequence similarities	Belongs to the phage and mitochondrial RNA polymerase family. RuleBase RU003805

Ontologies

Keywords
Biological process	Transcription
Cellular component	DNA-directed RNA polymerase RuleBase RU003805
Molecular function	Nucleotidyltransferase RuleBase RU003805 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	transcription, DNA-dependent Inferred from electronic annotation. Source: InterPro
Molecular_function	DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed RNA polymerase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C5DNP3 [UniParc]. Last modified July 28, 2009. Version 1. Checksum: 8DB3C8E07781D20C	FASTA	1,289	145,974
	10 20 30 40 50 60 MLRFSRSCSR MLVSKRLTSQ LRCVSQTAFL RKPSGNIDGL SGATGREDIG FLKSSSVSMS 70 80 90 100 110 120 PHFGPFDHSH AVVSAAESRD IMNLWSLLEA CLHSGYMERA FSILKSLYAL KSHQAYFIDD 130 140 150 160 170 180 YNKFLMKYAE TLHDIKDLDK KLFHDIQETF PACEYNDKTL AILIHHALKL SSSAEAKLEH 190 200 210 220 230 240 CKIYFKMAVS GQRSILSNVD VLTVPNYKSL VHDLKLVSLN ELPAAVRPLI ESGNIVTGEM 250 260 270 280 290 300 LSSQQSSEIN AKALSHGEVA LDRNIEPLDK DAKELLAVDT IGMKVVRHTL LGLSFTEDQK 310 320 330 340 350 360 KQITSFNFDT SSNLLNFDQE KESIDFFEMF RNLKSEEERR SFESALDEFN QDRQHQLENR 370 380 390 400 410 420 ATDAAKERWR HDFEEAKSRG DLSIQKKLNI KLWEWFNLML PLVKEEVRRC AAVANKTAQD 430 440 450 460 470 480 TSLSPQEKKQ NKARQEYGPY LTLVDPEKMC VITILELLKL NSTGGIIEGM RTARAVISVG 490 500 510 520 530 540 KAIEMEFRAE MLLKNESHVF KDVNKKSHEF KLMVQRARAT FRSIKIEESK VLWPQEARAK 550 560 570 580 590 600 IGSILISMLI HVAKVKVEGV DPVTNEKIKG EAPAFSHGYQ YHNGSKLGVL KIHRSLIHQL 610 620 630 640 650 660 NGERLVAAVQ PQLLPMLVKP RAWNSWNSGG YYYTQSTLIR SKDSPEQVAY LKAVSDAGAI 670 680 690 700 710 720 DNVYRGLNVL GETPWTVNRK MFNVMSQVWN SGKPFLDIPG IQEKLTLTPQ PPRDADPSVH 730 740 750 760 770 780 REWKLKNKEL ANEFSGNRSA RCDANYKLEI ARAFLGEKFY FPHNLDFRGR AYPLSPHFNH 790 800 810 820 830 840 LGNDMSRGLM TFWHGKRLGS TGLRWLKVHL SNLFGFDKAP LEDRVRFAED HIDDIRDSAE 850 860 870 880 890 900 HPLDGKCWWK EADKPWQALA TCMELNEALK MSNPDDFVSH QPVHQDGTCN GLQHYAALGG 910 920 930 940 950 960 DIEGATQVNL VPSDRPQDVY SHVAKLVVAR LEKAAANGDE TAALLKDKIK RKVVKQTVMT 970 980 990 1000 1010 1020 NVYGVTYIGA THQIDKQLST LFNDHKRSYE LSKYLTKHVF ASVRELFEGA HLIQDWLGEC 1030 1040 1050 1060 1070 1080 AKRISKSIRL DVDEKTLKNG NKPDFMSSVI WTTPLGLPIV QPYRENGKKQ VATNLQTVFI 1090 1100 1110 1120 1130 1140 SDPFAINPIN ARRQKAGFPP NFIHSLDASH MLLSAAKCGE KGLDFAAVHD SYWTHACDVD 1150 1160 1170 1180 1190 1200 TMNVVLREQF IKLHEVDLIE RLKDEFDERY KNYLQILKID KKSEVAMKVT DLKKKLSQKL 1210 1220 1230 1240 1250 1260 GRPFTLADEI YMEKKRIQLL SSEDASEQAE GANMVTTVSL VAGAGDISNL EKTSDASCLV 1270 1280 VLAPLTLPQI PPKGDFDVRE LEKSKYFFS

References

[1]

"Comparative genomics of protoploid Saccharomycetaceae." The Genolevures Consortium Souciet J.-L., Dujon B., Gaillardin C., Johnston M., Baret P.V., Cliften P., Sherman D.J., Weissenbach J., Westhof E., Wincker P., Jubin C., Poulain J., Barbe V., Segurens B., Artiguenave F., Anthouard V., Vacherie B., Val M.-E. , Fulton R.S., Minx P., Wilson R., Durrens P., Jean G., Marck C., Martin T., Nikolski M., Rolland T., Seret M.-L., Casaregola S., Despons L., Fairhead C., Fischer G., Lafontaine I., Leh V., Lemaire M., de Montigny J., Neuveglise C., Thierry A., Blanc-Lenfle I., Bleykasten C., Diffels J., Fritsch E., Frangeul L., Goeffon A., Jauniaux N., Kachouri-Lafond R., Payen C., Potier S., Pribylova L., Ozanne C., Richard G.-F., Sacerdot C., Straub M.-L., Talla E. Genome Res. 19:1696-1709(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 56472 / CBS 6340 / NRRL Y-8284.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CU928171 Genomic DNA. Translation: CAR25404.1.
RefSeq	XP_002555841.1. XM_002555795.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	559295.KLTH0G18744g.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	8294136.
KEGG	lth:KLTH0G18744g.
Phylogenomic databases
eggNOG	COG5108.
HOGENOM	HOG000248537.
KO	K10908.
OrthoDB	EOG4M0J8T.
Family and domain databases
Gene3D	1.10.287.260. 1 hit.
InterPro	IPR024075. DNA-dir_RNA_pol_helix_hairpin. IPR002092. DNA-dir_Rpol_phage-type. [Graphical view]
PANTHER	PTHR10102. PTHR10102. 1 hit.
Pfam	PF00940. RNA_pol. 1 hit. [Graphical view]
PROSITE	PS00900. RNA_POL_PHAGE_1. 1 hit. PS00489. RNA_POL_PHAGE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

C5DNP3_LACTC

Accession

Primary (citable) accession number: C5DNP3

Entry history

Integrated into UniProtKB/TrEMBL:	July 28, 2009
Last sequence update:	July 28, 2009
Last modified:	May 1, 2013
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)