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Protein

Superoxide dismutase

Gene

KLTH0G05192g

Organism
Lachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284) (Yeast) (Kluyveromyces thermotolerans)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Destroys radicals which are normally produced within the cells and which are toxic to biological systems.UniRule annotation

Catalytic activityi

2 superoxide + 2 H+ = O2 + H2O2.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi47Divalent metal cationUniRule annotation1
Metal bindingi104Divalent metal cationUniRule annotation1
Metal bindingi191Divalent metal cationUniRule annotation1
Metal bindingi195Divalent metal cationUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotation
LigandMetal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Superoxide dismutaseUniRule annotation (EC:1.15.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:KLTH0G05192gImported
OrganismiLachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284) (Yeast) (Kluyveromyces thermotolerans)Imported
Taxonomic identifieri559295 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeLachancea
Proteomesi
  • UP000002036 Componenti: Chromosome G

Subcellular locationi

GO - Cellular componenti

Interactioni

Protein-protein interaction databases

STRINGi381046.XP_002555264.1.

Structurei

3D structure databases

ProteinModelPortaliC5DM16.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini24 – 112Sod_Fe_NInterPro annotationAdd BLAST89
Domaini122 – 224Sod_Fe_CInterPro annotationAdd BLAST103

Sequence similaritiesi

Belongs to the iron/manganese superoxide dismutase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000013583.
InParanoidiC5DM16.
KOiK04564.
OrthoDBiEOG092C4NQ6.

Family and domain databases

InterProiView protein in InterPro
IPR001189. Mn/Fe_SOD.
IPR019833. Mn/Fe_SOD_BS.
IPR019832. Mn/Fe_SOD_C.
IPR019831. Mn/Fe_SOD_N.
PfamiView protein in Pfam
PF02777. Sod_Fe_C. 1 hit.
PF00081. Sod_Fe_N. 1 hit.
PIRSFiPIRSF000349. SODismutase. 1 hit.
PRINTSiPR01703. MNSODISMTASE.
SUPFAMiSSF46609. SSF46609. 1 hit.
SSF54719. SSF54719. 1 hit.
PROSITEiView protein in PROSITE
PS00088. SOD_MN. 1 hit.

Sequencei

Sequence statusi: Complete.

C5DM16-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFSRRIVQKA PGFAAVLGRR TKVTLPDLDW DFGALEPHIS GQINELHYSK
60 70 80 90 100
HHQTYVNGFN AATEQFGELT EKLTGDAQQD APLARKLAAL QQNIKFHGGG
110 120 130 140 150
FANHCLFWKN LAPESQGGGE APAGALGRQI ESQFGSLDKL QALTNAKLAG
160 170 180 190 200
VQGSGWAFIV KNAENGGQIE VVQTYNQDTV SGPLTPLVAI DAWEHAYYLQ
210 220
YQNRKADYFK AIWNVINWKE AERRFDAA
Length:228
Mass (Da):25,215
Last modified:July 28, 2009 - v1
Checksum:i9C55E726E5FA6141
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU928171 Genomic DNA. Translation: CAR24827.1.
RefSeqiXP_002555264.1. XM_002555218.1.

Genome annotation databases

EnsemblFungiiCAR24827; CAR24827; KLTH0G05192g.
GeneIDi8293530.
KEGGilth:KLTH0G05192g.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiC5DM16_LACTC
AccessioniPrimary (citable) accession number: C5DM16
Entry historyiIntegrated into UniProtKB/TrEMBL: July 28, 2009
Last sequence update: July 28, 2009
Last modified: July 5, 2017
This is version 46 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported