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Protein

Superoxide dismutase

Gene

KLTH0G05192g

Organism
Lachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284) (Yeast) (Kluyveromyces thermotolerans)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Destroys radicals which are normally produced within the cells and which are toxic to biological systems.UniRule annotation

Catalytic activityi

2 superoxide + 2 H+ = O2 + H2O2.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi47Divalent metal cationUniRule annotation1
Metal bindingi104Divalent metal cationUniRule annotation1
Metal bindingi191Divalent metal cationUniRule annotation1
Metal bindingi195Divalent metal cationUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotation
LigandMetal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Superoxide dismutaseUniRule annotation (EC:1.15.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:KLTH0G05192gImported
OrganismiLachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284) (Yeast) (Kluyveromyces thermotolerans)Imported
Taxonomic identifieri559295 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeLachancea
Proteomesi
  • UP000002036 Componenti: Chromosome G

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Interactioni

Protein-protein interaction databases

STRINGi381046.XP_002555264.1

Structurei

3D structure databases

ProteinModelPortaliC5DM16
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini24 – 112Sod_Fe_NInterPro annotationAdd BLAST89
Domaini122 – 224Sod_Fe_CInterPro annotationAdd BLAST103

Sequence similaritiesi

Belongs to the iron/manganese superoxide dismutase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000013583
InParanoidiC5DM16
KOiK04564
OrthoDBiEOG092C4NQ6

Family and domain databases

Gene3Di1.10.287.990, 1 hit
2.40.500.20, 1 hit
InterProiView protein in InterPro
IPR001189 Mn/Fe_SOD
IPR019833 Mn/Fe_SOD_BS
IPR019832 Mn/Fe_SOD_C
IPR019831 Mn/Fe_SOD_N
IPR036324 Mn/Fe_SOD_N_sf
IPR036314 SOD_C_sf
PfamiView protein in Pfam
PF02777 Sod_Fe_C, 1 hit
PF00081 Sod_Fe_N, 1 hit
PIRSFiPIRSF000349 SODismutase, 1 hit
PRINTSiPR01703 MNSODISMTASE
SUPFAMiSSF46609 SSF46609, 1 hit
SSF54719 SSF54719, 1 hit
PROSITEiView protein in PROSITE
PS00088 SOD_MN, 1 hit

Sequencei

Sequence statusi: Complete.

C5DM16-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFSRRIVQKA PGFAAVLGRR TKVTLPDLDW DFGALEPHIS GQINELHYSK
60 70 80 90 100
HHQTYVNGFN AATEQFGELT EKLTGDAQQD APLARKLAAL QQNIKFHGGG
110 120 130 140 150
FANHCLFWKN LAPESQGGGE APAGALGRQI ESQFGSLDKL QALTNAKLAG
160 170 180 190 200
VQGSGWAFIV KNAENGGQIE VVQTYNQDTV SGPLTPLVAI DAWEHAYYLQ
210 220
YQNRKADYFK AIWNVINWKE AERRFDAA
Length:228
Mass (Da):25,215
Last modified:July 28, 2009 - v1
Checksum:i9C55E726E5FA6141
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU928171 Genomic DNA Translation: CAR24827.1
RefSeqiXP_002555264.1, XM_002555218.1

Genome annotation databases

EnsemblFungiiCAR24827; CAR24827; KLTH0G05192g
GeneIDi8293530
KEGGilth:KLTH0G05192g

Similar proteinsi

Entry informationi

Entry nameiC5DM16_LACTC
AccessioniPrimary (citable) accession number: C5DM16
Entry historyiIntegrated into UniProtKB/TrEMBL: July 28, 2009
Last sequence update: July 28, 2009
Last modified: March 28, 2018
This is version 48 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health