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C5DIP3

- C5DIP3_LACTC

UniProt

C5DIP3 - C5DIP3_LACTC

Protein

Glutamate decarboxylase

Gene

KLTH0E14080g

Organism
Lachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284) (Yeast) (Kluyveromyces thermotolerans)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 27 (01 Oct 2014)
      Sequence version 1 (28 Jul 2009)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotation

    GO - Molecular functioni

    1. glutamate decarboxylase activity Source: InterPro
    2. pyridoxal phosphate binding Source: InterPro

    GO - Biological processi

    1. glutamate metabolic process Source: InterPro

    Keywords - Molecular functioni

    DecarboxylaseUniRule annotation, Lyase

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
    Gene namesi
    Ordered Locus Names:KLTH0E14080gImported
    OrganismiLachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284) (Yeast) (Kluyveromyces thermotolerans)Imported
    Taxonomic identifieri559295 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeLachancea
    ProteomesiUP000002036: Chromosome E

    Interactioni

    Protein-protein interaction databases

    STRINGi559295.KLTH0E14080g.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the group II decarboxylase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0076.
    HOGENOMiHOG000070228.
    KOiK01580.
    OrthoDBiEOG7P2Z22.

    Family and domain databases

    Gene3Di3.40.640.10. 1 hit.
    InterProiIPR010107. Glutamate_decarboxylase.
    IPR002129. PyrdxlP-dep_de-COase.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    [Graphical view]
    PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
    PfamiPF00282. Pyridoxal_deC. 1 hit.
    [Graphical view]
    SUPFAMiSSF53383. SSF53383. 1 hit.
    TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    C5DIP3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLHKHNPKHV HERSEHFGRS GDSLSNSYKL LSDDLQKIAL EGDSELQTKH    50
    RSLGSSYTIP QTGLPSEAAY ELVHNELTLD GNPHLNLASF VSTTSTQTAR 100
    RLIMENIEKN LADNDEYPQM IELTQRCISM LAQLWKCGKD TKPLGCATTG 150
    SSEAIMLGGL AMKRQWEKKM KEAGKSTEKP NIIMSSAAQV ALEKFARYFD 200
    VECRLVPVSH ESDHHLDAAK LWDYVDENTI GCYVILGTTY TGHLENVEEV 250
    ADVLSQIEKQ NPGWGNTTIP IHVDGASGGF VVPFAFSEKQ MAAFKLARWG 300
    FNHPRVVSIN TSGHKFGLTT PGLGWILWKD DEYLLPELRF KLTYLGGVEE 350
    TFNLNFSRPG FQVIHQYYNF LTLGEKGYKS LFDKALFTAR TFSHALLESD 400
    EFKGHFEVVS SIHERIDGGE SRLHDYMTEP ESFKPGVPLV AFKLSKQFHE 450
    KYPEIPQALV SSLLRSHGWI VPNYPLPAST DGSDKWEVLR VVFRSEMSLD 500
    LAQLLLSHIL RALRKLVKCY EGVAETADVD QRRDAIYRML LTLAEPEGAE 550
    PSEEDAKKRR KNYRGTC 567
    Length:567
    Mass (Da):63,971
    Last modified:July 28, 2009 - v1
    Checksum:iF8B13256998B6F14
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CU928169 Genomic DNA. Translation: CAR23654.1.
    RefSeqiXP_002554091.1. XM_002554045.1.

    Genome annotation databases

    GeneIDi8292260.
    KEGGilth:KLTH0E14080g.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CU928169 Genomic DNA. Translation: CAR23654.1 .
    RefSeqi XP_002554091.1. XM_002554045.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 559295.KLTH0E14080g.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 8292260.
    KEGGi lth:KLTH0E14080g.

    Phylogenomic databases

    eggNOGi COG0076.
    HOGENOMi HOG000070228.
    KOi K01580.
    OrthoDBi EOG7P2Z22.

    Family and domain databases

    Gene3Di 3.40.640.10. 1 hit.
    InterProi IPR010107. Glutamate_decarboxylase.
    IPR002129. PyrdxlP-dep_de-COase.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    [Graphical view ]
    PANTHERi PTHR11999:SF1. PTHR11999:SF1. 1 hit.
    Pfami PF00282. Pyridoxal_deC. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53383. SSF53383. 1 hit.
    TIGRFAMsi TIGR01788. Glu-decarb-GAD. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Comparative genomics of protoploid Saccharomycetaceae."
      The Genolevures Consortium
      Souciet J.-L., Dujon B., Gaillardin C., Johnston M., Baret P.V., Cliften P., Sherman D.J., Weissenbach J., Westhof E., Wincker P., Jubin C., Poulain J., Barbe V., Segurens B., Artiguenave F., Anthouard V., Vacherie B., Val M.-E.
      , Fulton R.S., Minx P., Wilson R., Durrens P., Jean G., Marck C., Martin T., Nikolski M., Rolland T., Seret M.-L., Casaregola S., Despons L., Fairhead C., Fischer G., Lafontaine I., Leh V., Lemaire M., de Montigny J., Neuveglise C., Thierry A., Blanc-Lenfle I., Bleykasten C., Diffels J., Fritsch E., Frangeul L., Goeffon A., Jauniaux N., Kachouri-Lafond R., Payen C., Potier S., Pribylova L., Ozanne C., Richard G.-F., Sacerdot C., Straub M.-L., Talla E.
      Genome Res. 19:1696-1709(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 56472 / CBS 6340 / NRRL Y-8284Imported.

    Entry informationi

    Entry nameiC5DIP3_LACTC
    AccessioniPrimary (citable) accession number: C5DIP3
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 28, 2009
    Last sequence update: July 28, 2009
    Last modified: October 1, 2014
    This is version 27 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3