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C5DEQ7

- C5DEQ7_LACTC

UniProt

C5DEQ7 - C5DEQ7_LACTC

Protein

DNA ligase

Gene

KLTH0C11286g

Organism
Lachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284) (Yeast) (Kluyveromyces thermotolerans)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 34 (01 Oct 2014)
      Sequence version 1 (28 Jul 2009)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. DNA binding Source: InterPro
    3. DNA ligase (ATP) activity Source: UniProtKB-EC

    GO - Biological processi

    1. DNA ligation involved in DNA repair Source: InterPro
    2. DNA recombination Source: UniProtKB-KW
    3. DNA replication Source: UniProtKB-KW

    Keywords - Molecular functioni

    LigaseUniRule annotation

    Keywords - Biological processi

    DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotation, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
    Gene namesi
    Ordered Locus Names:KLTH0C11286gImported
    OrganismiLachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284) (Yeast) (Kluyveromyces thermotolerans)Imported
    Taxonomic identifieri559295 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeLachancea
    ProteomesiUP000002036: Chromosome C

    Interactioni

    Protein-protein interaction databases

    STRINGi559295.KLTH0C11286g.

    Structurei

    3D structure databases

    ProteinModelPortaliC5DEQ7.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG1793.
    HOGENOMiHOG000093622.
    KOiK10777.
    OrthoDBiEOG7QC84G.

    Family and domain databases

    Gene3Di2.40.50.140. 1 hit.
    InterProiIPR001357. BRCT_dom.
    IPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    [Graphical view]
    PfamiPF00533. BRCT. 1 hit.
    PF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    [Graphical view]
    SMARTiSM00292. BRCT. 1 hit.
    [Graphical view]
    SUPFAMiSSF50249. SSF50249. 1 hit.
    SSF52113. SSF52113. 2 hits.
    TIGRFAMsiTIGR00574. dnl1. 1 hit.
    PROSITEiPS50172. BRCT. 2 hits.
    PS00697. DNA_LIGASE_A1. 1 hit.
    PS00333. DNA_LIGASE_A2. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    C5DEQ7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDGNGKCPSE TDTSKISENE PHNFAPSPDF RWLCEELFHR LDAINEHRQE    50
    LGKAVTVKRV EIITCFIKLW RTTVGDDFFP ALRLMFPYRD PRAYHIKDFT 100
    LIKAVCKALN LSRDSLTERR LLNWKQYAGR GTSLSKFCVQ EISKRRKEPL 150
    PERQLTIDGL NEKLDELAKE ASGKKAWGTT GLSESHSFQF CLKNLSFLEL 200
    RYFFDIVLKN RVIGGLEHKF LACWHPDAQI YLGVVTDLKI LSKKLWNPSV 250
    RLDKRDLSIN IGHAFAPHLA KRLHVSYERI CSKLKHDFIL EEKMDGERIQ 300
    LHYVNGGSVL KFLSRRGIDF SHLYGQEVAR GVISQYLKLK SDVRDCVLDG 350
    EMVSYDKKRK IILPFGIVKS AAVDELINSE VGNENDGYRP LYMVFDLVYL 400
    NGVSLTKVPL HIRKEYLKEI LSPVPDVVEI LKGIRACDAK AIKNFMQRAI 450
    EMGSEGVIVK QASSTYEVGA RNDHWVKIKP EYFEDLGETM DLVVIGRDPG 500
    KKDSLMCGLL VSDSEHILEN FGPIEHGKEG DPIIKCVSFC NVANGVSDEE 550
    FKEINRKTRG SWVSYKEKPP PLSLLEFGSK IPVEWIDPKN SVVIEVKARS 600
    VENSEYSSKR YRAGSTLHSA YCRRIRNDKD WTTCTSVAQY QQAKAAHNYH 650
    RYKRKVHQVS PRRKRNVHEI FEYCAGEAKS ELDTEGSSIF EGLHFYILSD 700
    YVTSQRRRYE RGMVAAKVVK HGGLIVKNID MRPEHLSYLR IVSGKTTIEC 750
    RNLVNRGYDI IDPCWIFDCI SAGFQLGIEP KHCFQTSRRL LDNSRQRVDQ 800
    YGDSFSRPLD TTEFQQLFKF FCSSPSDFSS RISSMLQDDL DEAPLFLLQR 850
    FKIYVLAADL IPQQFSILRR KIELYGGVVS ETLEGANLVL VPSALSTART 900
    AYYVQELRQK IAGNAFAGNT NTRIPHIVRS EWLDTCTTEQ CLVPEEDFSS 950
    I 951
    Length:951
    Mass (Da):108,867
    Last modified:July 28, 2009 - v1
    Checksum:i6F40D1836C666F1E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CU928167 Genomic DNA. Translation: CAR22268.1.
    RefSeqiXP_002552706.1. XM_002552660.1.

    Genome annotation databases

    GeneIDi8291592.
    KEGGilth:KLTH0C11286g.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CU928167 Genomic DNA. Translation: CAR22268.1 .
    RefSeqi XP_002552706.1. XM_002552660.1.

    3D structure databases

    ProteinModelPortali C5DEQ7.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 559295.KLTH0C11286g.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 8291592.
    KEGGi lth:KLTH0C11286g.

    Phylogenomic databases

    eggNOGi COG1793.
    HOGENOMi HOG000093622.
    KOi K10777.
    OrthoDBi EOG7QC84G.

    Family and domain databases

    Gene3Di 2.40.50.140. 1 hit.
    InterProi IPR001357. BRCT_dom.
    IPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    [Graphical view ]
    Pfami PF00533. BRCT. 1 hit.
    PF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    [Graphical view ]
    SMARTi SM00292. BRCT. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50249. SSF50249. 1 hit.
    SSF52113. SSF52113. 2 hits.
    TIGRFAMsi TIGR00574. dnl1. 1 hit.
    PROSITEi PS50172. BRCT. 2 hits.
    PS00697. DNA_LIGASE_A1. 1 hit.
    PS00333. DNA_LIGASE_A2. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Comparative genomics of protoploid Saccharomycetaceae."
      The Genolevures Consortium
      Souciet J.-L., Dujon B., Gaillardin C., Johnston M., Baret P.V., Cliften P., Sherman D.J., Weissenbach J., Westhof E., Wincker P., Jubin C., Poulain J., Barbe V., Segurens B., Artiguenave F., Anthouard V., Vacherie B., Val M.-E.
      , Fulton R.S., Minx P., Wilson R., Durrens P., Jean G., Marck C., Martin T., Nikolski M., Rolland T., Seret M.-L., Casaregola S., Despons L., Fairhead C., Fischer G., Lafontaine I., Leh V., Lemaire M., de Montigny J., Neuveglise C., Thierry A., Blanc-Lenfle I., Bleykasten C., Diffels J., Fritsch E., Frangeul L., Goeffon A., Jauniaux N., Kachouri-Lafond R., Payen C., Potier S., Pribylova L., Ozanne C., Richard G.-F., Sacerdot C., Straub M.-L., Talla E.
      Genome Res. 19:1696-1709(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 56472 / CBS 6340 / NRRL Y-8284Imported.

    Entry informationi

    Entry nameiC5DEQ7_LACTC
    AccessioniPrimary (citable) accession number: C5DEQ7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: July 28, 2009
    Last sequence update: July 28, 2009
    Last modified: October 1, 2014
    This is version 34 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3