C5DEQ7 (C5DEQ7_LACTC) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
DNA ligase RuleBase RU000617
EC=6.5.1.1 RuleBase RU000617

Gene names

Ordered Locus Names:

KLTH0C11286g

Organism

Lachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284) (Yeast) (Kluyveromyces thermotolerans) [Complete proteome] EMBL CAR22268.1

Taxonomic identifier

559295 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Lachancea › Lachancea thermotolerans

Protein attributes

Sequence length	951 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m). RuleBase RU000617
Sequence similarities	Belongs to the ATP-dependent DNA ligase family. RuleBase RU004196

Ontologies

Keywords
Biological process	DNA damage DNA recombination RuleBase RU000617 DNA repair RuleBase RU000617 DNA replication RuleBase RU000617
Ligand	ATP-binding RuleBase RU000617 Nucleotide-binding
Molecular function	Ligase RuleBase RU000617
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	DNA ligation involved in DNA repair Inferred from electronic annotation. Source: InterPro DNA recombination Inferred from electronic annotation. Source: UniProtKB-KW DNA replication Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW DNA binding Inferred from electronic annotation. Source: InterPro DNA ligase (ATP) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C5DEQ7 [UniParc]. Last modified July 28, 2009. Version 1. Checksum: 6F40D1836C666F1E	FASTA	951	108,867
	10 20 30 40 50 60 MDGNGKCPSE TDTSKISENE PHNFAPSPDF RWLCEELFHR LDAINEHRQE LGKAVTVKRV 70 80 90 100 110 120 EIITCFIKLW RTTVGDDFFP ALRLMFPYRD PRAYHIKDFT LIKAVCKALN LSRDSLTERR 130 140 150 160 170 180 LLNWKQYAGR GTSLSKFCVQ EISKRRKEPL PERQLTIDGL NEKLDELAKE ASGKKAWGTT 190 200 210 220 230 240 GLSESHSFQF CLKNLSFLEL RYFFDIVLKN RVIGGLEHKF LACWHPDAQI YLGVVTDLKI 250 260 270 280 290 300 LSKKLWNPSV RLDKRDLSIN IGHAFAPHLA KRLHVSYERI CSKLKHDFIL EEKMDGERIQ 310 320 330 340 350 360 LHYVNGGSVL KFLSRRGIDF SHLYGQEVAR GVISQYLKLK SDVRDCVLDG EMVSYDKKRK 370 380 390 400 410 420 IILPFGIVKS AAVDELINSE VGNENDGYRP LYMVFDLVYL NGVSLTKVPL HIRKEYLKEI 430 440 450 460 470 480 LSPVPDVVEI LKGIRACDAK AIKNFMQRAI EMGSEGVIVK QASSTYEVGA RNDHWVKIKP 490 500 510 520 530 540 EYFEDLGETM DLVVIGRDPG KKDSLMCGLL VSDSEHILEN FGPIEHGKEG DPIIKCVSFC 550 560 570 580 590 600 NVANGVSDEE FKEINRKTRG SWVSYKEKPP PLSLLEFGSK IPVEWIDPKN SVVIEVKARS 610 620 630 640 650 660 VENSEYSSKR YRAGSTLHSA YCRRIRNDKD WTTCTSVAQY QQAKAAHNYH RYKRKVHQVS 670 680 690 700 710 720 PRRKRNVHEI FEYCAGEAKS ELDTEGSSIF EGLHFYILSD YVTSQRRRYE RGMVAAKVVK 730 740 750 760 770 780 HGGLIVKNID MRPEHLSYLR IVSGKTTIEC RNLVNRGYDI IDPCWIFDCI SAGFQLGIEP 790 800 810 820 830 840 KHCFQTSRRL LDNSRQRVDQ YGDSFSRPLD TTEFQQLFKF FCSSPSDFSS RISSMLQDDL 850 860 870 880 890 900 DEAPLFLLQR FKIYVLAADL IPQQFSILRR KIELYGGVVS ETLEGANLVL VPSALSTART 910 920 930 940 950 AYYVQELRQK IAGNAFAGNT NTRIPHIVRS EWLDTCTTEQ CLVPEEDFSS I

References

[1]

"Comparative genomics of protoploid Saccharomycetaceae." The Genolevures Consortium Souciet J.-L., Dujon B., Gaillardin C., Johnston M., Baret P.V., Cliften P., Sherman D.J., Weissenbach J., Westhof E., Wincker P., Jubin C., Poulain J., Barbe V., Segurens B., Artiguenave F., Anthouard V., Vacherie B., Val M.-E. , Fulton R.S., Minx P., Wilson R., Durrens P., Jean G., Marck C., Martin T., Nikolski M., Rolland T., Seret M.-L., Casaregola S., Despons L., Fairhead C., Fischer G., Lafontaine I., Leh V., Lemaire M., de Montigny J., Neuveglise C., Thierry A., Blanc-Lenfle I., Bleykasten C., Diffels J., Fritsch E., Frangeul L., Goeffon A., Jauniaux N., Kachouri-Lafond R., Payen C., Potier S., Pribylova L., Ozanne C., Richard G.-F., Sacerdot C., Straub M.-L., Talla E. Genome Res. 19:1696-1709(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 56472 / CBS 6340 / NRRL Y-8284.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CU928167 Genomic DNA. Translation: CAR22268.1.
RefSeq	XP_002552706.1. XM_002552660.1.
3D structure databases
ProteinModelPortal	C5DEQ7.
ModBase	Search...
Protein-protein interaction databases
STRING	559295.KLTH0C11286g.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	8291592.
KEGG	lth:KLTH0C11286g.
Phylogenomic databases
eggNOG	COG1793.
HOGENOM	HOG000093622.
KO	K10777.
OrthoDB	EOG41K2MD.
Family and domain databases
Gene3D	2.40.50.140. 1 hit.
InterPro	IPR001357. BRCT_dom. IPR000977. DNA_ligase_ATP-dep. IPR012309. DNA_ligase_ATP-dep_C. IPR012310. DNA_ligase_ATP-dep_cent. IPR016059. DNA_ligase_ATP-dep_CS. IPR012308. DNA_ligase_ATP-dep_N. IPR012340. NA-bd_OB-fold. [Graphical view]
Pfam	PF00533. BRCT. 1 hit. PF04679. DNA_ligase_A_C. 1 hit. PF01068. DNA_ligase_A_M. 1 hit. PF04675. DNA_ligase_A_N. 1 hit. [Graphical view]
SMART	SM00292. BRCT. 1 hit. [Graphical view]
SUPFAM	SSF52113. BRCT. 2 hits. SSF50249. Nucleic_acid_OB. 1 hit.
TIGRFAMs	TIGR00574. dnl1. 1 hit.
PROSITE	PS50172. BRCT. 2 hits. PS00697. DNA_LIGASE_A1. 1 hit. PS00333. DNA_LIGASE_A2. 1 hit. PS50160. DNA_LIGASE_A3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

C5DEQ7_LACTC

Accession

Primary (citable) accession number: C5DEQ7

Entry history

Integrated into UniProtKB/TrEMBL:	July 28, 2009
Last sequence update:	July 28, 2009
Last modified:	May 1, 2013
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)