Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Cobalt-precorrin-5B C(1)-methyltransferase

Gene

cbiD

Organism
Geobacillus sp. (strain WCH70)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.UniRule annotation

Catalytic activityi

Cobalt-precorrin-5B + S-adenosyl-L-methionine = cobalt-precorrin-6A + S-adenosyl-L-homocysteine.UniRule annotation

Pathwayi: adenosylcobalamin biosynthesis

This protein is involved in step 6 of the subpathway that synthesizes cob(II)yrinate a,c-diamide from sirohydrochlorin (anaerobic route).UniRule annotation
Proteins known to be involved in the 10 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. no protein annotated in this organism
  3. no protein annotated in this organism
  4. no protein annotated in this organism
  5. no protein annotated in this organism
  6. Cobalt-precorrin-5B C(1)-methyltransferase (cbiD)
  7. no protein annotated in this organism
  8. no protein annotated in this organism
  9. no protein annotated in this organism
  10. Cobyrinate a,c-diamide synthase (cbiA)
This subpathway is part of the pathway adenosylcobalamin biosynthesis, which is itself part of Cofactor biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes cob(II)yrinate a,c-diamide from sirohydrochlorin (anaerobic route), the pathway adenosylcobalamin biosynthesis and in Cofactor biosynthesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMethyltransferase, Transferase
Biological processCobalamin biosynthesis
LigandS-adenosyl-L-methionine

Enzyme and pathway databases

UniPathwayiUPA00148; UER00227

Names & Taxonomyi

Protein namesi
Recommended name:
Cobalt-precorrin-5B C(1)-methyltransferaseUniRule annotation (EC:2.1.1.195UniRule annotation)
Alternative name(s):
Cobalt-precorrin-6A synthaseUniRule annotation
Gene namesi
Name:cbiDUniRule annotation
Ordered Locus Names:GWCH70_1554
OrganismiGeobacillus sp. (strain WCH70)
Taxonomic identifieri471223 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeGeobacillus
Proteomesi
  • UP000002386 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10002129381 – 365Cobalt-precorrin-5B C(1)-methyltransferaseAdd BLAST365

Proteomic databases

PRIDEiC5DAN8

Interactioni

Protein-protein interaction databases

STRINGi471223.GWCH70_1554

Structurei

3D structure databases

ProteinModelPortaliC5DAN8
SMRiC5DAN8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the CbiD family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105EE8 Bacteria
COG1903 LUCA
HOGENOMiHOG000009126
KOiK02188
OMAiGGIFHTH
OrthoDBiPOG091H02QJ

Family and domain databases

Gene3Di3.30.2110.10, 1 hit
HAMAPiMF_00787 CbiD, 1 hit
InterProiView protein in InterPro
IPR002748 CbiD
IPR036074 CbiD_sf
PANTHERiPTHR35863 PTHR35863, 1 hit
PfamiView protein in Pfam
PF01888 CbiD, 1 hit
PIRSFiPIRSF026782 CbiD, 1 hit
SUPFAMiSSF111342 SSF111342, 1 hit
TIGRFAMsiTIGR00312 cbiD, 1 hit

Sequencei

Sequence statusi: Complete.

C5DAN8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
METKKTLREG YTTGACATAA TKAALTALIT GIIQTEATIY LPVGRWATFA
60 70 80 90 100
IEACEIYGES VKATVIKDGG DDPDATHGAA IVSTVSWAEQ PGIHLDGGKG
110 120 130 140 150
VGRVTKPGLP VPVGEAAINP IPRKMIHETA REVLEQYGIS RGVNVIISVP
160 170 180 190 200
NGEEIAKKTL NARLGIIGGI SILGTRGIVI PFSTSAYRAS IIQAIQVAKA
210 220 230 240 250
NGCDHVVITT GGRSEKFAMR QYPHLPEEAF IEMGDFVGFT LKQCKRLGIR
260 270 280 290 300
TVSMVGMMGK FSKVAQGIMM VHSKSAPIDF SFLAAIAEQA GASPELVAAV
310 320 330 340 350
REANTASQVG EMMQEAGNER FFEILCDHCC LSALREVGGG MTVETSLYTM
360
GGQLLGKAVR NDAGD
Length:365
Mass (Da):38,544
Last modified:July 28, 2009 - v1
Checksum:i4FF8CD0C6A7D2256
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001638 Genomic DNA Translation: ACS24352.1
RefSeqiWP_015863810.1, NC_012793.1

Genome annotation databases

EnsemblBacteriaiACS24352; ACS24352; GWCH70_1554
KEGGigwc:GWCH70_1554

Similar proteinsi

Entry informationi

Entry nameiCBID_GEOSW
AccessioniPrimary (citable) accession number: C5DAN8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: July 28, 2009
Last modified: May 23, 2018
This is version 52 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health