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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Geobacillus sp. (strain WCH70)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:GWCH70_3348
OrganismiGeobacillus sp. (strain WCH70)
Taxonomic identifieri471223 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeGeobacillus
Proteomesi
  • UP000002386 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10002030971 – 556Arginine--tRNA ligaseAdd BLAST556

Proteomic databases

PRIDEiC5D9R0.

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi471223.GWCH70_3348.

Structurei

3D structure databases

ProteinModelPortaliC5D9R0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi132 – 142"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C75. Bacteria.
COG0018. LUCA.
HOGENOMiHOG000247214.
KOiK01887.
OMAiAGNQIEN.
OrthoDBiPOG091H01RF.

Family and domain databases

CDDicd00671. ArgRS_core. 1 hit.
Gene3Di3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth. 1 hit.
InterProiView protein in InterPro
IPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR036695. Arg-tRNA-synth_N_sf.
IPR035684. ArgRS_core.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_Ia_anticodon-bd.
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiView protein in Pfam
PF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
PRINTSiPR01038. TRNASYNTHARG.
SMARTiView protein in SMART
SM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiView protein in PROSITE
PS00178. AA_TRNA_LIGASE_I. 1 hit.

Sequencei

Sequence statusi: Complete.

C5D9R0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNIVEQMKER IKEEIKRAVV SAGFAAEEEV PEVILEVPRE KAHGDYSTNM
60 70 80 90 100
AMQLARIAKK PPRAIAEEIV QHMDKTKASI EKIDIAGPGF INFYMDNRYL
110 120 130 140 150
TELIPTIIQA GASYGETNVG KGQKVQVEFV SANPTGDLHL GHARGAAVGD
160 170 180 190 200
SLCNILEKAG FDVTREYYIN DAGNQIYNLA KSVEARYFQA LGIDKEMPED
210 220 230 240 250
GYYGEDIIEI GKKLAEEHGD KYVHMDEQER LAFFREYGLN YELEKIKKDL
260 270 280 290 300
ADFRVTFDVW YSETSLYTSG KIDETLALLR ERGHIYEKDG ATWFRSTTFG
310 320 330 340 350
DDKDRVLIKK DGTYTYLLPD IAYHQDKLRR GFTKIINIWG ADHHGYIPRM
360 370 380 390 400
KAAIEALGYD PDVLEVEIIQ LVNLYQNGER VKMSKRTGKA VTMRELMEEV
410 420 430 440 450
GLDATRYFFA MRSSDTHLDF DMDLAVSQSN ENPVYYVQYA HARVSSILRQ
460 470 480 490 500
GEELQLSYEG DLQLDYIQTE KEIELLKKLG EFPSAVSEAA IKRMPHRITG
510 520 530 540 550
YVFELASALH SFYNAEKVLD PENIEKSRAR LALMKAVQIT LQNALALIGV

SAPEKM
Length:556
Mass (Da):63,189
Last modified:July 28, 2009 - v1
Checksum:i6DEF74B5C33DC53B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001638 Genomic DNA. Translation: ACS25988.1.
RefSeqiWP_015865351.1. NC_012793.1.

Genome annotation databases

EnsemblBacteriaiACS25988; ACS25988; GWCH70_3348.
KEGGigwc:GWCH70_3348.

Similar proteinsi

Entry informationi

Entry nameiSYR_GEOSW
AccessioniPrimary (citable) accession number: C5D9R0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: July 28, 2009
Last modified: November 22, 2017
This is version 52 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families