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C5D975 (C5D975_GEOSW) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 36. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
UDP-N-acetylglucosamine 1-carboxyvinyltransferase HAMAP-Rule MF_00111

EC=2.5.1.7 HAMAP-Rule MF_00111
Alternative name(s):
Enoylpyruvate transferase HAMAP-Rule MF_00111
UDP-N-acetylglucosamine enolpyruvyl transferase HAMAP-Rule MF_00111
Gene names
Name:murA HAMAP-Rule MF_00111
Ordered Locus Names:GWCH70_3288 EMBL ACS25928.1
OrganismGeobacillus sp. (strain WCH70) [Complete proteome] [HAMAP] EMBL ACS25928.1
Taxonomic identifier471223 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesBacillaceaeGeobacillus

Protein attributes

Sequence length435 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine By similarity. SAAS SAAS005750 HAMAP-Rule MF_00111

Catalytic activity

Phosphoenolpyruvate + UDP-N-acetyl-alpha-D-glucosamine = phosphate + UDP-N-acetyl-3-O-(1-carboxyvinyl)-alpha-D-glucosamine. HAMAP-Rule MF_00111

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. SAAS SAAS005750 HAMAP-Rule MF_00111

Subcellular location

Cytoplasm By similarity SAAS SAAS005750 HAMAP-Rule MF_00111.

Sequence similarities

Belongs to the EPSP synthase family. MurA subfamily. HAMAP-Rule MF_00111

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1171Proton donor By similarity HAMAP-Rule MF_00111

Amino acid modifications

Modified residue11712-(S-cysteinyl)pyruvic acid O-phosphothioketal By similarity HAMAP-Rule MF_00111

Sequences

Sequence LengthMass (Da)Tools
C5D975 [UniParc].

Last modified July 28, 2009. Version 1.
Checksum: D9CBCB6895B29552

FASTA43546,549
        10         20         30         40         50         60 
MEKIIVRGGN RLSGTVKVEG AKNAVLPVIA ATLLASNGKS VIHDVPALSD VYTISEVLRY 

        70         80         90        100        110        120 
LGADVKIEEN TITVDASQEL KFEAPFEYVR KMRASVLVMG SLLARNGRAR VALPGGCAIG 

       130        140        150        160        170        180 
SRPIDQHLKG FEAMGAHVKV GNGFIDAEVK GRLRGAKIYL DFPSVGATEN IMMAAVLAEG 

       190        200        210        220        230        240 
TTIIENCAKE PEIVDLANFL NAMGAKVRGA GTGTIRIEGV DQLTGTTHTV IPDRIEAGTF 

       250        260        270        280        290        300 
MVAAAITGGN VLVQGAVPEH LSSLIAKMEE MGVTIIEEGN GLRVIGPEKL KAVDIKTMPY 

       310        320        330        340        350        360 
PGFPTDMQSQ MMALLLKAEG TSMVTETVFE NRFMHVEEFR RMNADIKIEG RSVIINGPCN 

       370        380        390        400        410        420 
LQGAEVAATD LRAAAALILA GLAAEGYTRV TELRHLDRGY VRFHEKLAAL GADIERVNDE 

       430 
SETAAEDVKV KDLNI 

« Hide

References

[1]"Complete sequence of chromosome of Geopacillus sp. WCH70."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N. expand/collapse author list , Brumm P., Mead D.A., Richardson P.
Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: WCH70 EMBL ACS25928.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001638 Genomic DNA. Translation: ACS25928.1.
RefSeqYP_002951194.1. NC_012793.1.

3D structure databases

ProteinModelPortalC5D975.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING471223.GWCH70_3288.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACS25928; ACS25928; GWCH70_3288.
GeneID7977195.
KEGGgwc:GWCH70_3288.
PATRIC21975699. VBIGeoSp101709_3430.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0766.
HOGENOMHOG000075602.
KOK00790.
OMAGYEHIED.
OrthoDBEOG68M4GK.
ProtClustDBPRK09369.

Enzyme and pathway databases

BioCycGSP471223:GH2C-3402-MONOMER.
UniPathwayUPA00219.

Family and domain databases

Gene3D3.65.10.10. 2 hits.
HAMAPMF_00111. MurA.
InterProIPR001986. Enolpyruvate_Tfrase_dom.
IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b.
IPR005750. UDP_GlcNAc_COvinyl_MurA.
[Graphical view]
PANTHERPTHR21090:SF4. PTHR21090:SF4. 1 hit.
PfamPF00275. EPSP_synthase. 1 hit.
[Graphical view]
SUPFAMSSF55205. SSF55205. 1 hit.
TIGRFAMsTIGR01072. murA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameC5D975_GEOSW
AccessionPrimary (citable) accession number: C5D975
Entry history
Integrated into UniProtKB/TrEMBL: July 28, 2009
Last sequence update: July 28, 2009
Last modified: February 19, 2014
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)