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Protein
Submitted name:

Sun protein

Gene

GWCH70_1064

Organism
Geobacillus sp. (strain WCH70)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.SAAS annotation

Catalytic activityi

S-adenosyl-L-methionine + cytosine(967) in 16S rRNA = S-adenosyl-L-homocysteine + 5-methylcytosine(967) in 16S rRNA.SAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei283S-adenosyl-L-methioninePROSITE-ProRule annotation1
Binding sitei310S-adenosyl-L-methioninePROSITE-ProRule annotation1
Binding sitei329S-adenosyl-L-methioninePROSITE-ProRule annotation1
Active sitei382NucleophilePROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMethyltransferasePROSITE-ProRule annotationSAAS annotation, RNA-bindingPROSITE-ProRule annotationSAAS annotation, Transferase
Biological processrRNA processingSAAS annotation
LigandS-adenosyl-L-methioninePROSITE-ProRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciGSP471223:GH2C-1070-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Sun proteinImported
Gene namesi
Ordered Locus Names:GWCH70_1064Imported
OrganismiGeobacillus sp. (strain WCH70)Imported
Taxonomic identifieri471223 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeGeobacillus
Proteomesi
  • UP000002386 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm SAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi471223.GWCH70_1064.

Structurei

3D structure databases

ProteinModelPortaliC5D8R7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini170 – 446SAM_MT_RSMB_NOPInterPro annotationAdd BLAST277

Sequence similaritiesi

Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.PROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105CYJ. Bacteria.
COG0144. LUCA.
HOGENOMiHOG000037300.
KOiK03500.
OMAiLRVNRQH.
OrthoDBiPOG091H02E2.

Family and domain databases

Gene3Di1.10.940.10. 1 hit.
InterProiView protein in InterPro
IPR018314. Fmu/NOL1/Nop2p_CS.
IPR001678. MeTrfase_RsmB/NOP2.
IPR006027. NusB_RsmB_TIM44.
IPR023267. RCMT.
IPR004573. rRNA_ssu_MeTfrase_B.
IPR029063. SAM-dependent_MTases.
PfamiView protein in Pfam
PF01189. Methyltr_RsmB-F. 1 hit.
PF01029. NusB. 1 hit.
PRINTSiPR02008. RCMTFAMILY.
SUPFAMiSSF48013. SSF48013. 1 hit.
SSF53335. SSF53335. 1 hit.
TIGRFAMsiTIGR00563. rsmB. 1 hit.
PROSITEiView protein in PROSITE
PS01153. NOL1_NOP2_SUN. 1 hit.
PS51686. SAM_MT_RSMB_NOP. 1 hit.

Sequencei

Sequence statusi: Complete.

C5D8R7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKAKNVREVA LETLLAVEEK EAYSNLLLNK MIETHRLSER DVRLLTEIVY
60 70 80 90 100
GTIQRRDTLD YYLTPFLKKA RKLERWVRVL LRLTLYQVLY LDRIPDRAAI
110 120 130 140 150
FEAVEIAKKR GHQGVASLVN GVMRAIQRQG VPPLEKIEDE VERLAVATSH
160 170 180 190 200
PLWLVKRWVE QYGLEETKRM CETNLLPPKQ TARVNTARIT VEEAIDKLKQ
210 220 230 240 250
EGMEVVLGEV AEEAIQAKRG NLAHTDAFRR GWITIQDESS MLVARALGPK
260 270 280 290 300
EHERVLDSCA APGGKSTHIA ELMNNTGQVI CADIHEHKVN LIEENAKRLQ
310 320 330 340 350
LTNISARVLD SRRLGEVFER EMFDKILVDA PCSGFGVIRR KPDIKYAKTE
360 370 380 390 400
ADIPSLVALQ REILHAVAPL LKKGGTLVYS TCTIDRDENE AVIAQFLDDH
410 420 430 440
PEFSPDETMK RRLPEKVQPY VHNGQLHLLP HYFGSDGFFI ASLRKKV
Length:447
Mass (Da):50,929
Last modified:July 28, 2009 - v1
Checksum:i9AD7C9DBCF310BD9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001638 Genomic DNA. Translation: ACS23924.1.
RefSeqiWP_015863398.1. NC_012793.1.

Genome annotation databases

EnsemblBacteriaiACS23924; ACS23924; GWCH70_1064.
KEGGigwc:GWCH70_1064.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiC5D8R7_GEOSW
AccessioniPrimary (citable) accession number: C5D8R7
Entry historyiIntegrated into UniProtKB/TrEMBL: July 28, 2009
Last sequence update: July 28, 2009
Last modified: June 7, 2017
This is version 63 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported