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Protein

Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex

Gene

GWCH70_3162

Organism
Geobacillus sp. (strain WCH70)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Cofactori

(R)-lipoateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAcyltransferaseUniRule annotation, Transferase

Enzyme and pathway databases

BioCyciGSP471223:GH2C-3000-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complexUniRule annotation (EC:2.3.1.-UniRule annotation)
Gene namesi
Ordered Locus Names:GWCH70_3162Imported
OrganismiGeobacillus sp. (strain WCH70)Imported
Taxonomic identifieri471223 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeGeobacillus
Proteomesi
  • UP000002386 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi471223.GWCH70_3162

Structurei

3D structure databases

ProteinModelPortaliC5D8I2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 77Lipoyl-bindingInterPro annotationAdd BLAST76
Domaini101 – 138Peripheral subunit-binding (PSBD)InterPro annotationAdd BLAST38

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili284 – 311Sequence analysisAdd BLAST28

Sequence similaritiesi

Belongs to the 2-oxoacid dehydrogenase family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis, LipoylUniRule annotation

Phylogenomic databases

eggNOGiENOG4105C7S Bacteria
COG0508 LUCA
HOGENOMiHOG000281564
KOiK00627
OMAiRAMAQNM
OrthoDBiPOG091H05OF

Family and domain databases

Gene3Di3.30.559.10, 1 hit
4.10.320.10, 1 hit
InterProiView protein in InterPro
IPR001078 2-oxoacid_DH_actylTfrase
IPR000089 Biotin_lipoyl
IPR023213 CAT-like_dom_sf
IPR036625 E3-bd_dom_sf
IPR004167 PSBD
IPR011053 Single_hybrid_motif
PfamiView protein in Pfam
PF00198 2-oxoacid_dh, 1 hit
PF00364 Biotin_lipoyl, 1 hit
PF02817 E3_binding, 1 hit
SUPFAMiSSF47005 SSF47005, 1 hit
SSF51230 SSF51230, 1 hit
PROSITEiView protein in PROSITE
PS50968 BIOTINYL_LIPOYL, 1 hit
PS51826 PSBD, 1 hit

Sequencei

Sequence statusi: Complete.

C5D8I2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRYEFKLPDI GEGLHEAEIV RWFIQEGDEV SVDQPIAEIQ TDKAMVEMTT
60 70 80 90 100
PVAGKVVALA GPEGATVKVG EPLIIVDQQK ASDHEEAAAE SKPAQRKKRV
110 120 130 140 150
IAAPSVRKRA REMGVPIEEV EGTGEGGRVT LADLERYVKE RESASAAVAP
160 170 180 190 200
ALEATEMPTV HKQTVNEERI PIRGLRKKIA EKMVKSAYTA PHVTGMDEID
210 220 230 240 250
VTKLVEIRTG LVKQLETESV KLTYLPFVIK AVTRALKEHP IFNATIDEET
260 270 280 290 300
NEIVLKKEYH IGIATATKEG LVVPVIKHAD QKSIRELAIE LAELSEKAHR
310 320 330 340 350
HTLRVDELQG STFTITSTGA NGGWFATPII NYPEVAILGV HSIKRKPAVI
360 370 380 390
GDEIVIRDMM GMSLTFDHRV IDGEPAGRFM RTVAQILEHP EQLLLDVR
Length:398
Mass (Da):43,952
Last modified:July 28, 2009 - v1
Checksum:i3D6EA08F70F2BB40
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001638 Genomic DNA Translation: ACS25820.1
RefSeqiWP_015865200.1, NC_012793.1

Genome annotation databases

EnsemblBacteriaiACS25820; ACS25820; GWCH70_3162
KEGGigwc:GWCH70_3162

Entry informationi

Entry nameiC5D8I2_GEOSW
AccessioniPrimary (citable) accession number: C5D8I2
Entry historyiIntegrated into UniProtKB/TrEMBL: July 28, 2009
Last sequence update: July 28, 2009
Last modified: March 28, 2018
This is version 55 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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