C5D4K5 (GATC_GEOSW) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C
Short name=Asp/Glu-ADT subunit C
EC=6.3.5.-

Gene names

Name:	gatC
Ordered Locus Names:	GWCH70_0286

Organism

Geobacillus sp. (strain WCH70) [Complete proteome] [HAMAP]

Taxonomic identifier

471223 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Geobacillus

Protein attributes

Sequence length	96 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) By similarity. HAMAP-Rule MF_00122
Catalytic activity	ATP + L-glutamyl-tRNA(Gln) + L-glutamine = ADP + phosphate + L-glutaminyl-tRNA(Gln) + L-glutamate. HAMAP-Rule MF_00122 ATP + L-aspartyl-tRNA(Asn) + L-glutamine = ADP + phosphate + L-asparaginyl-tRNA(Asn) + L-glutamate. HAMAP-Rule MF_00122
Subunit structure	Heterotrimer of A, B and C subunits By similarity.
Sequence similarities	Belongs to the GatC family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Ligand	ATP-binding Nucleotide-binding
Molecular function	Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	regulation of translational fidelity Inferred from electronic annotation. Source: InterPro translation Inferred from electronic annotation. Source: HAMAP
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 96	96	Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C HAMAP-Rule MF_00122		PRO_1000203072

Sequences

	Sequence		Length	Mass (Da)
	C5D4K5 [UniParc]. Last modified July 28, 2009. Version 1. Checksum: 55D98658709FC825	FASTA	96	10,827
	10 20 30 40 50 60 MSRISIEQVK HVAHLARLAI TDEEAEMFTK QLDAIITFAE QLNELDTENV PPTSHVLDMK 70 80 90 NVMREDVPTP GLPLEEVLKN APDHQDGQFR VPAILE

References

[1]

"Complete sequence of chromosome of Geopacillus sp. WCH70." US DOE Joint Genome Institute Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N. , Brumm P., Mead D.A., Richardson P. Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: WCH70.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001638 Genomic DNA. Translation: ACS23213.1.
RefSeq	YP_002948479.1. NC_012793.1.
3D structure databases
ProteinModelPortal	C5D4K5.
ModBase	Search...
Protein-protein interaction databases
STRING	471223.GWCH70_0286.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACS23213; ACS23213; GWCH70_0286.
GeneID	7976151.
KEGG	gwc:GWCH70_0286.
PATRIC	21969358. VBIGeoSp101709_0322.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0721.
HOGENOM	HOG000017523.
KO	K02435.
OMA	HAVPLTN.
ProtClustDB	PRK00034.
Enzyme and pathway databases
BioCyc	GSP471223:GH2C-379-MONOMER.
Family and domain databases
HAMAP	MF_00122. GatC.
InterPro	IPR003837. Asp/Glu-ADT_csu. [Graphical view]
Pfam	PF02686. Glu-tRNAGln. 1 hit. [Graphical view]
TIGRFAMs	TIGR00135. gatC. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GATC_GEOSW

Accession

Primary (citable) accession number: C5D4K5

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 22, 2009
Last sequence update:	July 28, 2009
Last modified:	May 1, 2013
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program