C5D4D3 (C5D4D3_GEOSW) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Alanine racemase RuleBase RU000608
EC=5.1.1.1 RuleBase RU000608

Gene names

Ordered Locus Names:

GWCH70_0210 EMBL ACS23141.1

Organism

Geobacillus sp. (strain WCH70) [Complete proteome] [HAMAP] EMBL ACS23141.1

Taxonomic identifier

471223 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Geobacillus

Protein attributes

Sequence length	387 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	L-alanine = D-alanine. RuleBase RU000608 SAAS SAAS020622
Cofactor	Pyridoxal phosphate By similarity. RuleBase RU000608 SAAS SAAS020622
Pathway	Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. SAAS SAAS020622 RuleBase RU004247
Sequence similarities	Belongs to the alanine racemase family. RuleBase RU004188

Ontologies

Keywords
Ligand	Pyridoxal phosphate RuleBase RU000608 SAAS SAAS020622
Molecular function	Isomerase RuleBase RU000608 SAAS SAAS020622 EMBL ACS23141.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	D-alanine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	alanine racemase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	C5D4D3 [UniParc]. Last modified July 28, 2009. Version 1. Checksum: 66637A3B6A4C9966	FASTA	387	43,964
	10 20 30 40 50 60 MSNLFYRDTW AEIDLDAIYY NVSQLKNFLQ NDIRIMAVVK ANAYGHGDVQ VAKTALEAGA 70 80 90 100 110 120 SYLAVAFLDE AIALRKKGVT APILVLGACR PSDINIAAKH RITLTVFQPE WIEQAANVYS 130 140 150 160 170 180 ETSPVLFHLK MDTGMGRLGV REETETKRVI EQIDRHPYFS LEGAYTHFAT ADEINTDYFS 190 200 210 220 230 240 FQYDNFLRML EWLPYKPPII HCGNSATALR FPDKAFNMVR FGISMYGLSP SPEIKQYLPY 250 260 270 280 290 300 ELKEAFSLHS RLVHVKKLKP GEKVSYGATY TAETEQWVGT VPIGYADGWL RKLQNFHVLV 310 320 330 340 350 360 NGEKAPIIGR ICMDQLMVRL PKQMPVGTKV TLIGRQGDEY ISVDDVAQYL GTINYEVPCT 370 380 ISYRVPRIFF RNKSIMEVRN FVLDGND

References

[1]

"Complete sequence of chromosome of Geopacillus sp. WCH70." US DOE Joint Genome Institute Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N. , Brumm P., Mead D.A., Richardson P. Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: WCH70 EMBL ACS23141.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001638 Genomic DNA. Translation: ACS23141.1.
RefSeq	YP_002948407.1. NC_012793.1.
3D structure databases
ProteinModelPortal	C5D4D3.
SMR	C5D4D3. Positions 3-382.
ModBase	Search...
Protein-protein interaction databases
STRING	471223.GWCH70_0210.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACS23141; ACS23141; GWCH70_0210.
GeneID	7977953.
KEGG	gwc:GWCH70_0210.
PATRIC	21969157. VBIGeoSp101709_0240.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0787.
HOGENOM	HOG000031444.
KO	K01775.
OMA	IRLPKAY.
ProtClustDB	CLSK712473.
Enzyme and pathway databases
BioCyc	GSP471223:GH2C-285-MONOMER.
UniPathway	UPA00042; UER00497.
Family and domain databases
Gene3D	2.40.37.10. 1 hit.
HAMAP	MF_01201. Ala_racemase.
InterPro	IPR000821. Ala_racemase. IPR009006. Ala_racemase/Decarboxylase_C. IPR011079. Ala_racemase_C. IPR001608. Ala_racemase_N. IPR020622. Ala_racemase_pyridoxalP-BS. [Graphical view]
Pfam	PF00842. Ala_racemase_C. 1 hit. PF01168. Ala_racemase_N. 1 hit. [Graphical view]
PRINTS	PR00992. ALARACEMASE.
SMART	SM01005. Ala_racemase_C. 1 hit. [Graphical view]
SUPFAM	SSF50621. Racem_decarbox_C. 1 hit.
TIGRFAMs	TIGR00492. alr. 1 hit.
PROSITE	PS00395. ALANINE_RACEMASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

C5D4D3_GEOSW

Accession

Primary (citable) accession number: C5D4D3

Entry history

Integrated into UniProtKB/TrEMBL:	July 28, 2009
Last sequence update:	July 28, 2009
Last modified:	May 1, 2013
This is version 37 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)