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C5D4D3 (C5D4D3_GEOSW) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Alanine racemase RuleBase RU004247 HAMAP-Rule MF_01201

EC=5.1.1.1 RuleBase RU004247 HAMAP-Rule MF_01201
Gene names
Ordered Locus Names:GWCH70_0210 EMBL ACS23141.1
OrganismGeobacillus sp. (strain WCH70) [Complete proteome] [HAMAP] EMBL ACS23141.1
Taxonomic identifier471223 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesBacillaceaeGeobacillus

Protein attributes

Sequence length387 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. RuleBase RU004247 HAMAP-Rule MF_01201 SAAS SAAS009006

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS009006

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201 RuleBase RU004188

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site401Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2661Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1371Substrate By similarity HAMAP-Rule MF_01201
Binding site3131Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue401N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
C5D4D3 [UniParc].

Last modified July 28, 2009. Version 1.
Checksum: 66637A3B6A4C9966

FASTA38743,964
        10         20         30         40         50         60 
MSNLFYRDTW AEIDLDAIYY NVSQLKNFLQ NDIRIMAVVK ANAYGHGDVQ VAKTALEAGA 

        70         80         90        100        110        120 
SYLAVAFLDE AIALRKKGVT APILVLGACR PSDINIAAKH RITLTVFQPE WIEQAANVYS 

       130        140        150        160        170        180 
ETSPVLFHLK MDTGMGRLGV REETETKRVI EQIDRHPYFS LEGAYTHFAT ADEINTDYFS 

       190        200        210        220        230        240 
FQYDNFLRML EWLPYKPPII HCGNSATALR FPDKAFNMVR FGISMYGLSP SPEIKQYLPY 

       250        260        270        280        290        300 
ELKEAFSLHS RLVHVKKLKP GEKVSYGATY TAETEQWVGT VPIGYADGWL RKLQNFHVLV 

       310        320        330        340        350        360 
NGEKAPIIGR ICMDQLMVRL PKQMPVGTKV TLIGRQGDEY ISVDDVAQYL GTINYEVPCT 

       370        380 
ISYRVPRIFF RNKSIMEVRN FVLDGND 

« Hide

References

[1]"Complete sequence of chromosome of Geopacillus sp. WCH70."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N. expand/collapse author list , Brumm P., Mead D.A., Richardson P.
Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: WCH70 EMBL ACS23141.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001638 Genomic DNA. Translation: ACS23141.1.
RefSeqYP_002948407.1. NC_012793.1.

3D structure databases

ProteinModelPortalC5D4D3.
SMRC5D4D3. Positions 3-382.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING471223.GWCH70_0210.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACS23141; ACS23141; GWCH70_0210.
GeneID7977953.
KEGGgwc:GWCH70_0210.
PATRIC21969157. VBIGeoSp101709_0240.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0787.
HOGENOMHOG000031444.
KOK01775.
OMAMAHFADA.
OrthoDBEOG6PP9NJ.
ProtClustDBCLSK712473.

Enzyme and pathway databases

BioCycGSP471223:GH2C-251-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC5D4D3_GEOSW
AccessionPrimary (citable) accession number: C5D4D3
Entry history
Integrated into UniProtKB/TrEMBL: July 28, 2009
Last sequence update: July 28, 2009
Last modified: February 19, 2014
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)