ID   C5D385_GEOSW            Unreviewed;       826 AA.
AC   C5D385;
DT   28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   28-JUL-2009, sequence version 1.
DT   27-MAR-2024, entry version 67.
DE   SubName: Full=Stage II sporulation protein E, protein serine/threonine phosphatase {ECO:0000313|EMBL:ACS23001.1};
DE            EC=3.1.3.16 {ECO:0000313|EMBL:ACS23001.1};
GN   OrderedLocusNames=GWCH70_0059 {ECO:0000313|EMBL:ACS23001.1};
OS   Geobacillus sp. (strain WCH70).
OC   Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Geobacillus.
OX   NCBI_TaxID=471223 {ECO:0000313|EMBL:ACS23001.1};
RN   [1] {ECO:0000313|EMBL:ACS23001.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WCH70 {ECO:0000313|EMBL:ACS23001.1};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA   Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C.,
RA   Han C., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N.,
RA   Brumm P., Mead D.A., Richardson P.;
RT   "Complete sequence of chromosome of Geopacillus sp. WCH70.";
RL   Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP001638; ACS23001.1; -; Genomic_DNA.
DR   AlphaFoldDB; C5D385; -.
DR   STRING; 471223.GWCH70_0059; -.
DR   KEGG; gwc:GWCH70_0059; -.
DR   eggNOG; COG2208; Bacteria.
DR   HOGENOM; CLU_017349_0_0_9; -.
DR   OrthoDB; 9763774at2; -.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0017018; F:myosin phosphatase activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR   InterPro; IPR036457; PPM-type-like_dom_sf.
DR   InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR   InterPro; IPR014221; SpoII_E.
DR   InterPro; IPR045768; SpoIIE_N.
DR   NCBIfam; TIGR02865; spore_II_E; 1.
DR   PANTHER; PTHR43156:SF12; STAGE II SPORULATION PROTEIN E; 1.
DR   PANTHER; PTHR43156; STAGE II SPORULATION PROTEIN E-RELATED; 1.
DR   Pfam; PF07228; SpoIIE; 1.
DR   Pfam; PF19732; SpoIIE_N; 1.
DR   SMART; SM00331; PP2C_SIG; 1.
DR   SMART; SM00332; PP2Cc; 1.
DR   SUPFAM; SSF81606; PP2C-like; 1.
DR   PROSITE; PS51746; PPM_2; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:ACS23001.1};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        35..52
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        83..116
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        128..148
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        160..182
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        194..214
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        226..250
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        256..274
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          596..806
FT                   /note="PPM-type phosphatase"
FT                   /evidence="ECO:0000259|PROSITE:PS51746"
SQ   SEQUENCE   826 AA;  92732 MW;  5AF85125047FAB06 CRC64;
     MERVERRFMN QISEVPIHET QAVLSRWVRH VKLRVGHLFI HKGFLLLIIG FLLGRALILS
     KLTPFALPFF AAVYMLRRDK AALAFIALLA GSLTLSFEAT LFVFVGIFGF LVVNAFIRKF
     FSESLKMVPF VVFCLSFSTK LAIFYYLLGN RTLYEAMMAF VEAGLAFVLT LIFIQSIPLL
     MIRKYKQALR AEEIISLIIL IASMLTGMIG WTFYGLSLEH VMSRYLVLIF AFVAGATIGS
     TVGVVTGLIL SLANVGNLYE MSLLAFAGLL GGLLKEGKKA GVSFGLLIAT LLIGLYGSGK
     AEIIPTVMES FLAIILFAFT SRSLTEKIAK HIPGTAEYAN EQQQYVRKIR DVTAQRVSQF
     SHVFQALANS FSTKSLISSD EDYSEREIDY FLSDITEKTC QTCFKKEQCW SYNFNTTYEY
     MKQIMLEADA GILEHNHKLL REWDNHCVKA SKVVDMIEKD VTFYQANRKL RKQMNESRKL
     VAEQLLGVSQ VMEDFAKEIQ RERENHYLQE EQIFHALQEF GIEIGHVDIY SLEKGNIDIE
     MSIPYCEGRG ECEKLIAPML SDILGETIVV KREECAAYPN GYCRVAFGST KAFVVETGVA
     FAAKGGGLVS GDSYSMIELG TGKYAIAISD GMGNGERAHN ESNETLRLLQ EILQTGIDES
     IAIKSVNSIL SLRTTEDMFS TLDLAIIDLQ NAVTKFLKVG STPSFVKRGD KVMKIEASNL
     PIGIIKEADF EIVSEQLKAG DLLIMMSDGV FEGPPHVENY DLWMKRKIKE LKTNDPQEVA
     DLIMEEVIRS RSGRIEDDMT VVVAKIKHNT PKWATIPAYM YIKKAQ
//