Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Variovorax paradoxus (strain S110)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei154 – 1541UniRule annotation
Active sitei599 – 5991UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciVPAR543728:GHLL-1382-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:Vapar_1373Imported
OrganismiVariovorax paradoxus (strain S110)Imported
Taxonomic identifieri543728 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesComamonadaceaeVariovorax
ProteomesiUP000000453: Chromosome 1

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi543728.Vapar_1373.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiFTSNWEL.
OrthoDBiEOG6TJ7T8.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C5CSC6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKASKTPAPP KRRQAEDQPL IDDIRLLGRI LGDVIREQEG EESYALVEKI
60 70 80 90 100
RTLSVAFRRD ADQAADRALK NLLKGLSAAE TVRVIRAFTY FSHLANLAED
110 120 130 140 150
RHLIRRRTEA ERAGESADGD LQTALARIRK AGVKPDEVVA SLARSYVSPV
160 170 180 190 200
LTAHPTEVQR KSILDAERAI AQLLTTRDEI KLRQSAYAGA KDALTPLEFA
210 220 230 240 250
ENETQMRIRV TQIWQTRLLR FSKLTVADEI ENALSYYEAT FLREIPRVYA
260 270 280 290 300
DLEKALGQGG VLPSVAPFLR MGQWIGGDRD GNPNVTAETL EYALRRQAEL
310 320 330 340 350
ALRHYLTEVH YLGGELSLSA TLVDVSVEMQ ALAARSPDTS EHRKDEPYRR
360 370 380 390 400
ALTGVYARLA ATLRDLTGGE AARHAVPPQN PYAKAEEFLD DLRTVEESLV
410 420 430 440 450
EKHGSVLAAP RLRPLIRAVE VFGFHLATVD LRQSSDKHEA VIAELLATAR
460 470 480 490 500
IEPAYASLAE EAKQTLLLKL LDDARPLRVP DAEYSPLAQS ELAIFAAART
510 520 530 540 550
ARARYGAAAI RHYIISHTET VSDLLEALLL QKEVGLLRGA MNGKATCDLI
560 570 580 590 600
VVPLFETIED LRNAAPIVRA FYALPNIQAL IERSGAEQDV MLGYSDSNKD
610 620 630 640 650
GGIFTSNWEL YRAGIALVAL FDELNKKKAN PIRLRMFHGR GGTVGRGGGP
660 670 680 690 700
SYQAILAQPP GTVRGQIRLT EQGEVIGSKY ANREIGRRNL ETLVAATLEA
710 720 730 740 750
TLLPQAKSAP ATFLSAAGEL STASMSAYRK LVYETPGFGD YFFGSTPIRE
760 770 780 790 800
IAELNIGSRP ASRNPSHKID DLRAVPWSFS WGQCRLTIPG WFGFGSGVEQ
810 820 830 840 850
FLASAATPAA RKERTALLRR MYAQWPFFRT LLSNMDMVLA KSDLALASRY
860 870 880 890 900
AELVTDRKLR QKVFSMIDTE WHRTSDALTL ITGAKQRLEG NAEMQRSVRH
910 920 930 940
RFPYIDPLHH LQVELMRRYR AGEGGERLQR GIHISINGVA AGLRNTG
Length:947
Mass (Da):104,960
Last modified:July 28, 2009 - v1
Checksum:i4DA0808176344CFE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001635 Genomic DNA. Translation: ACS18024.1.
RefSeqiYP_002943290.1. NC_012791.1.

Genome annotation databases

EnsemblBacteriaiACS18024; ACS18024; Vapar_1373.
GeneIDi7973054.
KEGGivap:Vapar_1373.
PATRICi24003170. VBIVarPar36677_1392.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001635 Genomic DNA. Translation: ACS18024.1.
RefSeqiYP_002943290.1. NC_012791.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi543728.Vapar_1373.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACS18024; ACS18024; Vapar_1373.
GeneIDi7973054.
KEGGivap:Vapar_1373.
PATRICi24003170. VBIVarPar36677_1392.

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiFTSNWEL.
OrthoDBiEOG6TJ7T8.

Enzyme and pathway databases

BioCyciVPAR543728:GHLL-1382-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete genome sequence of the metabolically versatile plant growth-promoting endophyte, Variovorax paradoxus S110."
    Han J.I., Choi H.K., Lee S.W., Orwin P.M., Kim J., Laroe S.L., Kim T.G., O'Neil J., Leadbetter J.R., Lee S.Y., Hur C.G., Spain J.C., Ovchinnikova G., Goodwin L., Han C.
    J. Bacteriol. 193:1183-1190(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: S110Imported.

Entry informationi

Entry nameiC5CSC6_VARPS
AccessioniPrimary (citable) accession number: C5CSC6
Entry historyi
Integrated into UniProtKB/TrEMBL: July 28, 2009
Last sequence update: July 28, 2009
Last modified: February 4, 2015
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.