ID   C5CM41_VARPS            Unreviewed;       430 AA.
AC   C5CM41;
DT   28-JUL-2009, integrated into UniProtKB/TrEMBL.
DT   28-JUL-2009, sequence version 1.
DT   27-MAR-2024, entry version 66.
DE   SubName: Full=4-aminobutyrate aminotransferase {ECO:0000313|EMBL:ACS21300.1};
GN   OrderedLocusNames=Vapar_4695 {ECO:0000313|EMBL:ACS21300.1};
OS   Variovorax paradoxus (strain S110).
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Comamonadaceae; Variovorax.
OX   NCBI_TaxID=543728 {ECO:0000313|EMBL:ACS21300.1};
RN   [1] {ECO:0000313|EMBL:ACS21300.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=S110 {ECO:0000313|EMBL:ACS21300.1};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D.,
RA   Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C., Han C.,
RA   Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Orwin P.,
RA   Leadbetter J.R., Spain J.C., Han J.I.;
RT   "Complete sequence of chromosome 1 of Variovorax paradoxus S110.";
RL   Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933};
CC   -!- SIMILARITY: Belongs to the class-III pyridoxal-phosphate-dependent
CC       aminotransferase family. {ECO:0000256|ARBA:ARBA00008954,
CC       ECO:0000256|RuleBase:RU003560}.
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DR   EMBL; CP001635; ACS21300.1; -; Genomic_DNA.
DR   AlphaFoldDB; C5CM41; -.
DR   STRING; 543728.Vapar_4695; -.
DR   KEGG; vap:Vapar_4695; -.
DR   eggNOG; COG0160; Bacteria.
DR   HOGENOM; CLU_016922_10_0_4; -.
DR   OrthoDB; 3398487at2; -.
DR   GO; GO:0003867; F:4-aminobutyrate transaminase activity; IEA:InterPro.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0009448; P:gamma-aminobutyric acid metabolic process; IEA:InterPro.
DR   CDD; cd00610; OAT_like; 1.
DR   Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   InterPro; IPR004632; 4NH2But_aminotransferase_bac.
DR   InterPro; IPR005814; Aminotrans_3.
DR   InterPro; IPR049704; Aminotrans_3_PPA_site.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR   NCBIfam; TIGR00700; GABAtrnsam; 1.
DR   PANTHER; PTHR11986; AMINOTRANSFERASE CLASS III; 1.
DR   PANTHER; PTHR11986:SF58; LEUCINE_METHIONINE RACEMASE; 1.
DR   Pfam; PF00202; Aminotran_3; 1.
DR   PIRSF; PIRSF000521; Transaminase_4ab_Lys_Orn; 2.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR   PROSITE; PS00600; AA_TRANSFER_CLASS_3; 1.
PE   3: Inferred from homology;
KW   Aminotransferase {ECO:0000256|ARBA:ARBA00022576,
KW   ECO:0000313|EMBL:ACS21300.1};
KW   Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW   ECO:0000256|RuleBase:RU003560}; Transferase {ECO:0000313|EMBL:ACS21300.1}.
SQ   SEQUENCE   430 AA;  45308 MW;  6CCB5DF036D5C2CD CRC64;
     MQREPHLSNA ALMARRNAAV ARGVGQAHEI FVSRAANAEV WDVEGRRYID FAGGIAVLNT
     GHCHPEISAA VKAQVDLYSH TCFQVLAYEP YVELAERLNA LAPGNFAKKS IFLSTGAEAV
     ENAVKIARAH TRRPGVIAFN GGYHGRTMMT LGLTGKVAPY KLGFGPFPGE VFHALYPNVL
     HGVSVDDALH SVELLFKNDI EPERVAAFIL EPVQGEGGFY VAPNDFVEGL RALADRHGIL
     IIADEVQTGA GRTGTWFASE QWPVAPDLIT TAKSMAGGFP ISGVVGRAEV MDAPAPGGLG
     GTYAGSPIGC AAALAVLKVF DDEQLLARSR ALGGRLTAGL RRIAAGVPAI GDVRGLGAMV
     AIELFEDGDT ARPDAGLTRR VVAEAARRGL ILLSCGTYGN VIRVLVPLTA SDLLVDEGLA
     LLADSFAALR
//