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C5CHW9

- ARGB_KOSOT

UniProt

C5CHW9 - ARGB_KOSOT

Protein

Acetylglutamate kinase

Gene

argB

Organism
Kosmotoga olearia (strain TBF 19.5.1)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 34 (01 Oct 2014)
      Sequence version 1 (28 Jul 2009)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamate 5-phosphate.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sitei27 – 271Transition state stabilizerUniRule annotation
    Binding sitei84 – 841SubstrateUniRule annotation
    Binding sitei178 – 1781SubstrateUniRule annotation
    Sitei237 – 2371Transition state stabilizerUniRule annotation

    GO - Molecular functioni

    1. acetylglutamate kinase activity Source: UniProtKB-EC
    2. ATP binding Source: UniProtKB-KW

    GO - Biological processi

    1. arginine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Kinase, Transferase

    Keywords - Biological processi

    Amino-acid biosynthesis, Arginine biosynthesis

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciKOLE521045:GHRV-102-MONOMER.
    UniPathwayiUPA00068; UER00107.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Acetylglutamate kinaseUniRule annotation (EC:2.7.2.8UniRule annotation)
    Alternative name(s):
    N-acetyl-L-glutamate 5-phosphotransferaseUniRule annotation
    NAG kinaseUniRule annotation
    Short name:
    AGKUniRule annotation
    Gene namesi
    Name:argBUniRule annotation
    Ordered Locus Names:Kole_0096
    OrganismiKosmotoga olearia (strain TBF 19.5.1)
    Taxonomic identifieri521045 [NCBI]
    Taxonomic lineageiBacteriaThermotogaeThermotogalesThermotogaceaeKosmotoga
    ProteomesiUP000002382: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 282282Acetylglutamate kinasePRO_1000202564Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi521045.Kole_0096.

    Structurei

    3D structure databases

    ProteinModelPortaliC5CHW9.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni62 – 632Substrate bindingUniRule annotation

    Sequence similaritiesi

    Belongs to the acetylglutamate kinase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0548.
    HOGENOMiHOG000233259.
    KOiK00930.
    OrthoDBiEOG6T1WVF.

    Family and domain databases

    Gene3Di3.40.1160.10. 1 hit.
    HAMAPiMF_00082_A. ArgB_A.
    MF_00082_B. ArgB_B.
    InterProiIPR004662. AcgluKinase.
    IPR001048. Asp/Glu/Uridylate_kinase.
    [Graphical view]
    PfamiPF00696. AA_kinase. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000728. NAGK. 1 hit.
    SUPFAMiSSF53633. SSF53633. 1 hit.
    TIGRFAMsiTIGR00761. argB. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    C5CHW9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKRETVQVLL EALPYIKEFH GKTFVIKFGG SAMKNENAKE AFIKDLVLLK    50
    YTGINPVIVH GGGSEISSLM NQLGIEPVFK NGYRITDEKT MEIVEMVLVG 100
    KVNKDIVMNI NLHGGKAIGV CGKDGELLLA EKETKYGDIG YVGKVKKVDT 150
    TLIKGLLVEG YIPVIAPIGF GEDGTSYNIN ADIVAAEIAK SLEVEKLVLL 200
    TDVDGVFKDG KLLPILSSKE AEDLIEKNIV KGGMIPKLQC AISAVNSGVK 250
    SVHIINGGVE HALLLEIFSK EGIGTMIKNL EV 282
    Length:282
    Mass (Da):30,436
    Last modified:July 28, 2009 - v1
    Checksum:iC0EB1CF2ACDD0080
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001634 Genomic DNA. Translation: ACR78824.1.
    RefSeqiYP_002939828.1. NC_012785.1.

    Genome annotation databases

    EnsemblBacteriaiACR78824; ACR78824; Kole_0096.
    GeneIDi7967514.
    KEGGikol:Kole_0096.
    PATRICi22185290. VBIKosOle109242_0097.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001634 Genomic DNA. Translation: ACR78824.1 .
    RefSeqi YP_002939828.1. NC_012785.1.

    3D structure databases

    ProteinModelPortali C5CHW9.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 521045.Kole_0096.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACR78824 ; ACR78824 ; Kole_0096 .
    GeneIDi 7967514.
    KEGGi kol:Kole_0096.
    PATRICi 22185290. VBIKosOle109242_0097.

    Phylogenomic databases

    eggNOGi COG0548.
    HOGENOMi HOG000233259.
    KOi K00930.
    OrthoDBi EOG6T1WVF.

    Enzyme and pathway databases

    UniPathwayi UPA00068 ; UER00107 .
    BioCyci KOLE521045:GHRV-102-MONOMER.

    Family and domain databases

    Gene3Di 3.40.1160.10. 1 hit.
    HAMAPi MF_00082_A. ArgB_A.
    MF_00082_B. ArgB_B.
    InterProi IPR004662. AcgluKinase.
    IPR001048. Asp/Glu/Uridylate_kinase.
    [Graphical view ]
    Pfami PF00696. AA_kinase. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000728. NAGK. 1 hit.
    SUPFAMi SSF53633. SSF53633. 1 hit.
    TIGRFAMsi TIGR00761. argB. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequence of Thermotogales bacterium TBF 19.5.1."
      US DOE Joint Genome Institute
      Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Noll K.
      Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: TBF 19.5.1.

    Entry informationi

    Entry nameiARGB_KOSOT
    AccessioniPrimary (citable) accession number: C5CHW9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: September 22, 2009
    Last sequence update: July 28, 2009
    Last modified: October 1, 2014
    This is version 34 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3