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C5CC19 (C5CC19_MICLC) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 44. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length401 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP-Rule MF_01201 RuleBase RU004247 SAAS SAAS020622

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201 SAAS SAAS020622

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201 RuleBase RU004188

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site481Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2871Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1531Substrate By similarity HAMAP-Rule MF_01201
Binding site3341Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue481N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
C5CC19 [UniParc].

Last modified July 28, 2009. Version 1.
Checksum: 5D9FF6B66708B980

FASTA40141,672
        10         20         30         40         50         60 
MSRADVNPAD TERAVRIDLA AVRHNVGVLR ERIRRPDGSR PLLTAVVKAD AYGHGAVAVA 

        70         80         90        100        110        120 
RAAAAAGADR LGVAHVREAL ALRAAGVPLP VLAWLHTGAT DFAAAVEAEV TLGVSGWDLD 

       130        140        150        160        170        180 
AAADAVRGLR ARGGAGPEAR AVLHLKADTG LGRHGCTPER WPAFVARAAE LEAAGLVRVE 

       190        200        210        220        230        240 
GVFSHLGVAD EPDRAAETTA QLLRFERMAA EAAETLGHPL LRHLANTPAT LARPDTHLDM 

       250        260        270        280        290        300 
VRVGLGLYGL SPFAEVTAAE LGLRPAMSLV TVLANVKAVP AGQGVSYGFR HVTAEPTTLG 

       310        320        330        340        350        360 
LVPVGYADGV PRVVEGTRVH VGGRTVPVVG RIAMDQFVVD LGPDAADAPG DAVELFGPAS 

       370        380        390        400 
GIPVEEWAAA AGTINYELVT RIGGRVDRQH VDPTPTQEAR P 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001628 Genomic DNA. Translation: ACS31160.1.
RefSeqYP_002957714.1. NC_012803.1.

3D structure databases

ProteinModelPortalC5CC19.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING465515.Mlut_16720.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACS31160; ACS31160; Mlut_16720.
GeneID7985923.
KEGGmlu:Mlut_16720.
PATRIC22623982. VBIMicLut29563_1610.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0787.
HOGENOMHOG000031444.
KOK01775.
OrthoDBEOG6PP9NJ.

Enzyme and pathway databases

BioCycMLUT465515:GHH6-1669-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameC5CC19_MICLC
AccessionPrimary (citable) accession number: C5CC19
Entry history
Integrated into UniProtKB/TrEMBL: July 28, 2009
Last sequence update: July 28, 2009
Last modified: July 9, 2014
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)