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C5CBP5 (PGK_MICLC) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 31. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein attributes

Sequence length415 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate. HAMAP-Rule MF_00145

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5. HAMAP-Rule MF_00145

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00145

Subcellular location

Cytoplasm Potential HAMAP-Rule MF_00145.

Sequence similarities

Belongs to the phosphoglycerate kinase family.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglycolytic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoglycerate kinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 415415Phosphoglycerate kinase HAMAP-Rule MF_00145
PRO_1000203343

Regions

Nucleotide binding367 – 3704ATP By similarity
Region24 – 263Substrate binding By similarity
Region62 – 654Substrate binding By similarity

Sites

Binding site391Substrate By similarity
Binding site1211Substrate By similarity
Binding site1611Substrate By similarity
Binding site2111ATP By similarity
Binding site3071ATP; via carbonyl oxygen By similarity
Binding site3381ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
C5CBP5 [UniParc].

Last modified July 28, 2009. Version 1.
Checksum: 3D655285D4C7A3FA

FASTA41542,606
        10         20         30         40         50         60 
MPASTLNDLL EAGVTGRTVL IRSDLNVPLD GDTVTDDGRI RASLPAIRDL AEAGARVIVM 

        70         80         90        100        110        120 
AHLGRPKGEP DPAYSLRPVA ARMAELLGAD VALAADVTGD DARAQAAALQ DGQVLLLENV 

       130        140        150        160        170        180 
RFDARETSKD DAERAALAGE MAALAGEDGA YVGDAFGAVH RKHASVFDVA AQLPAYQGPL 

       190        200        210        220        230        240 
VAAELEVLTR LTESPEQPYV VVLGGSKVSD KLAVIDNLLD KADTLLIGGG MLFTFLKAQG 

       250        260        270        280        290        300 
HEVGASLLEE DQLDTVRAYL RRSEAGAARI VLPTDIVMAS GFAADAEHEV LAADALTSGA 

       310        320        330        340        350        360 
HGASAMGLDI GPETARAFAE QIRGAQTVFW NGPMGVFEFP AFAEGTRAVA RALTEASAAG 

       370        380        390        400        410 
GLSVVGGGDS AAAVRTLGFA DDAFGHISTG GGASLEYLEG KELPGVTALA GEGRA 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001628 Genomic DNA. Translation: ACS30642.1.
RefSeqYP_002957196.1. NC_012803.1.

3D structure databases

ProteinModelPortalC5CBP5.
SMRC5CBP5. Positions 5-411.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING465515.Mlut_11360.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACS30642; ACS30642; Mlut_11360.
GeneID7985798.
KEGGmlu:Mlut_11360.
PATRIC22622904. VBIMicLut29563_1078.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0126.
HOGENOMHOG000227107.
KOK00927.
OrthoDBEOG64N9Z0.

Enzyme and pathway databases

BioCycMLUT465515:GHH6-1133-MONOMER.
UniPathwayUPA00109; UER00185.

Family and domain databases

Gene3D3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPMF_00145. Phosphoglyc_kinase.
InterProIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERPTHR11406. PTHR11406. 1 hit.
PfamPF00162. PGK. 1 hit.
[Graphical view]
PIRSFPIRSF000724. Pgk. 1 hit.
PRINTSPR00477. PHGLYCKINASE.
SUPFAMSSF53748. SSF53748. 1 hit.
PROSITEPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePGK_MICLC
AccessionPrimary (citable) accession number: C5CBP5
Entry history
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: July 28, 2009
Last modified: June 11, 2014
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways