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Protein

Probable malate:quinone oxidoreductase

Gene

mqo

Organism
Micrococcus luteus (strain ATCC 4698 / DSM 20030 / JCM 1464 / NBRC 3333 / NCIMB 9278 / NCTC 2665 / VKM Ac-2230) (Micrococcus lysodeikticus)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

(S)-malate + a quinone = oxaloacetate + reduced quinone.UniRule annotation

Cofactori

FADUniRule annotation

Pathwayi: tricarboxylic acid cycle

This protein is involved in step 1 of the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route).UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Probable malate:quinone oxidoreductase (mqo)
This subpathway is part of the pathway tricarboxylic acid cycle, which is itself part of Carbohydrate metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route), the pathway tricarboxylic acid cycle and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
Biological processTricarboxylic acid cycle
LigandFAD, Flavoprotein

Enzyme and pathway databases

BioCyciMLUT465515:G1GEW-835-MONOMER
UniPathwayiUPA00223; UER01008

Names & Taxonomyi

Protein namesi
Recommended name:
Probable malate:quinone oxidoreductaseUniRule annotation (EC:1.1.5.4UniRule annotation)
Alternative name(s):
MQOUniRule annotation
Malate dehydrogenase [quinone]UniRule annotation
Gene namesi
Name:mqoUniRule annotation
Ordered Locus Names:Mlut_08440
OrganismiMicrococcus luteus (strain ATCC 4698 / DSM 20030 / JCM 1464 / NBRC 3333 / NCIMB 9278 / NCTC 2665 / VKM Ac-2230) (Micrococcus lysodeikticus)
Taxonomic identifieri465515 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaMicrococcalesMicrococcaceaeMicrococcus
Proteomesi
  • UP000000738 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10002042011 – 494Probable malate:quinone oxidoreductaseAdd BLAST494

Proteomic databases

PRIDEiC5CAA3

Interactioni

Protein-protein interaction databases

STRINGi465515.MlutN2_010100002916

Structurei

3D structure databases

ProteinModelPortaliC5CAA3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the MQO family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DWT Bacteria
COG0579 LUCA
HOGENOMiHOG000109379
KOiK00116
OMAiEPIAATK
OrthoDBiPOG091H0B7C

Family and domain databases

Gene3Di3.50.50.60, 2 hits
HAMAPiMF_00212 MQO, 1 hit
InterProiView protein in InterPro
IPR036188 FAD/NAD-bd_sf
IPR006231 MQO
PfamiView protein in Pfam
PF06039 Mqo, 1 hit
SUPFAMiSSF51905 SSF51905, 2 hits
TIGRFAMsiTIGR01320 mal_quin_oxido, 1 hit

Sequencei

Sequence statusi: Complete.

C5CAA3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPTTSSTATH DVVLIGGGIM SATLGVLLQK LEPTWSIALY ENLDQAGLES
60 70 80 90 100
SDPWNNAGTG HAALCELNYS PMDKNGRVDV TKALGINEQF WITRQFWSSL
110 120 130 140 150
VVDGTLKDPK SFINPLPHMS FVWGDDHADY LRARYEAMSA QPVFAGMEHS
160 170 180 190 200
EDPEQIRAWA PLLIEGRESG QRLAASRHTG GTDVDFGSLT RQLVTAMAGA
210 220 230 240 250
GAEVRFGHKV TGLTRGTDGR WEVKVKNKAA GSEVVDRARF VFVGAGGGAL
260 270 280 290 300
PLLQKSGIPE IKGFGGFPVS GQFLRCTDES VVNQHMAKVY GQAAVGAPPM
310 320 330 340 350
SVPHLDTRFV NGKRSLLFGP YAGFSTNFLK TGSYLDLPLS VRPHNLTTML
360 370 380 390 400
DVAKDNVDLT KYLVTEVLKS RDKKIDALHE FYPEADGGEW ELITAGQRVQ
410 420 430 440 450
VMKRKGRFGG VLQFGTEVVT HADGSLGGLL GASPGASTAA PIMVKLLERC
460 470 480 490
FPAKTAGWDG TLKELIPSLG HTLNDDPALL DEVRTVTDAA LKLA
Length:494
Mass (Da):53,202
Last modified:July 28, 2009 - v1
Checksum:i5952DD0742E06088
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001628 Genomic DNA Translation: ACS30372.1
RefSeqiWP_010078988.1, NZ_CABC01000037.1

Genome annotation databases

EnsemblBacteriaiACS30372; ACS30372; Mlut_08440
GeneIDi7986570
KEGGimlu:Mlut_08440
PATRICifig|465515.4.peg.807

Similar proteinsi

Entry informationi

Entry nameiMQO_MICLC
AccessioniPrimary (citable) accession number: C5CAA3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: July 28, 2009
Last modified: May 23, 2018
This is version 55 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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