SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

C5BW79

- DNLI_BEUC1

UniProt

C5BW79 - DNLI_BEUC1

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Probable DNA ligase
Gene
lig, Bcav_0272
Organism
Beutenbergia cavernae (strain ATCC BAA-8 / DSM 12333 / NBRC 16432)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair By similarity.UniRule annotation

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

Cofactori

Divalent metal cations By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei217 – 2171ATP By similarity
Active sitei219 – 2191N6-AMP-lysine intermediate By similarity
Binding sitei224 – 2241ATP By similarity
Binding sitei239 – 2391ATP By similarity
Binding sitei268 – 2681ATP By similarity
Binding sitei306 – 3061ATP By similarity
Binding sitei377 – 3771ATP By similarity
Binding sitei383 – 3831ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. DNA binding Source: InterPro
  3. DNA ligase (ATP) activity Source: UniProtKB-HAMAP
  4. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. DNA ligation involved in DNA repair Source: InterPro
  2. DNA recombination Source: UniProtKB-HAMAP
  3. DNA replication Source: UniProtKB-HAMAP
  4. cell cycle Source: UniProtKB-KW
  5. cell division Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Biological processi

Cell cycle, Cell division, DNA damage, DNA recombination, DNA repair, DNA replication

Keywords - Ligandi

ATP-binding, Metal-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciBCAV471853:GI1Z-275-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable DNA ligase (EC:6.5.1.1)
Alternative name(s):
Polydeoxyribonucleotide synthase [ATP]
Gene namesi
Name:lig
Ordered Locus Names:Bcav_0272
OrganismiBeutenbergia cavernae (strain ATCC BAA-8 / DSM 12333 / NBRC 16432)
Taxonomic identifieri471853 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesMicrococcineaeBeutenbergiaceaeBeutenbergia
ProteomesiUP000007962: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 512512Probable DNA ligaseUniRule annotation
PRO_1000205954Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi471853.Bcav_0272.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG1793.
HOGENOMiHOG000036008.
KOiK01971.
OMAiRKVKPVH.
OrthoDBiEOG6Q8HXT.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 2 hits.
HAMAPiMF_00407. DNA_ligase.
InterProiIPR022865. DNA_ligae_ATP-dep_bac/arc.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 2 hits.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

C5BW79-1 [UniParc]FASTAAdd to Basket

« Hide

MLLAEVAATS DAVAATRSRL AKRAAIADLL RRAPADDVEI VVAYVAGELR    50
QRRTGLGWRS LRDLPGPAED PSLEVADVDA TFAAMADLAG PGSATARAAA 100
AAELFAAATE REQALLRGLV SGELRQGALD ALVLDAVADA AGVPAPEVRR 150
AAMFAGATGP VARAALAAAG PAEAVAALSG FMLTVGRAVR PMLAQSAPDV 200
AAAFAKLPGG DVAVSVDVKL DGIRIQVHKA GDEVRVFTRS LDDITGRVPE 250
IVEAVRALPA GALVLDGEAL AVDAGGRPRP FQETASRSAT RDADVAAAMT 300
LTPFFFDCLH ADGRDLVDAP LRERLEVLDA VAGPHVVTRL TTSDPAAAEE 350
FFAAAVRDGQ EGVVVKATDT PYEAGRRGAG WIKVKPRHTL DLVVLAVEWG 400
SGRRRGWLSN IHLGARDPAG GFVMLGKTFK GMTDEMLAWQ TERFLELETS 450
RDEWAVHLRP EQVVEIAFDG LQRSTRYPGG LALRFARVLR YRDDKTAAEA 500
DTIDTVRTLA GL 512
Length:512
Mass (Da):53,976
Last modified:July 28, 2009 - v1
Checksum:iEC4172653DFF126F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001618 Genomic DNA. Translation: ACQ78537.1.
RefSeqiWP_012725317.1. NC_012669.1.
YP_002880299.1. NC_012669.1.

Genome annotation databases

EnsemblBacteriaiACQ78537; ACQ78537; Bcav_0272.
GeneIDi7860066.
KEGGibcv:Bcav_0272.
PATRICi21091073. VBIBeuCav91323_0275.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001618 Genomic DNA. Translation: ACQ78537.1 .
RefSeqi WP_012725317.1. NC_012669.1.
YP_002880299.1. NC_012669.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 471853.Bcav_0272.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACQ78537 ; ACQ78537 ; Bcav_0272 .
GeneIDi 7860066.
KEGGi bcv:Bcav_0272.
PATRICi 21091073. VBIBeuCav91323_0275.

Phylogenomic databases

eggNOGi COG1793.
HOGENOMi HOG000036008.
KOi K01971.
OMAi RKVKPVH.
OrthoDBi EOG6Q8HXT.

Enzyme and pathway databases

BioCyci BCAV471853:GI1Z-275-MONOMER.

Family and domain databases

Gene3Di 1.10.3260.10. 1 hit.
2.40.50.140. 2 hits.
HAMAPi MF_00407. DNA_ligase.
InterProi IPR022865. DNA_ligae_ATP-dep_bac/arc.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view ]
Pfami PF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 2 hits.
[Graphical view ]
SUPFAMi SSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsi TIGR00574. dnl1. 1 hit.
PROSITEi PS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-8 / DSM 12333 / NBRC 16432.

Entry informationi

Entry nameiDNLI_BEUC1
AccessioniPrimary (citable) accession number: C5BW79
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: July 28, 2009
Last modified: September 3, 2014
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi